Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kleinberg X. Fernandez"'
Autor:
Jeffrey Y. K. Wong, Arunika I. Ekanayake, Serhii Kharchenko, Steven E. Kirberger, Ryan Qiu, Payam Kelich, Susmita Sarkar, Jiaqian Li, Kleinberg X. Fernandez, Edgar R. Alvizo-Paez, Jiayuan Miao, Shiva Kalhor-Monfared, J. Dwyer John, Hongsuk Kang, Hwanho Choi, John M. Nuss, John C. Vederas, Yu-Shan Lin, Matthew S. Macauley, Lela Vukovic, William C. K. Pomerantz, Ratmir Derda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Peptide-based therapeutics have gained attention as promising therapeutic modalities, however, their prevalent drawback is poor circulation half-life in vivo. In this paper, we report the selection of albumin-binding macrocyclic peptides fro
Externí odkaz:
https://doaj.org/article/70cf58a7e9004f0fbc1e0c30b3084ed6
Autor:
Janet X. Li, Kleinberg X. Fernandez, Carol Ritland, Sharon Jancsik, Daniel B. Engelhardt, Lauren Coombe, René L. Warren, Marco J. van Belkum, Allan L. Carroll, John C. Vederas, Joerg Bohlmann, Inanc Birol
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background The mountain pine beetle, Dendroctonus ponderosae, is an irruptive bark beetle that causes extensive mortality to many pine species within the forests of western North America. Driven by climate change and wildfire suppression, a
Externí odkaz:
https://doaj.org/article/f1c847f5d68649eb800fc1971a3af89f
Autor:
Jeffrey Y. K. Wong, Arunika I. Ekanayake, Serhii Kharchenko, Steven E. Kirberger, Ryan Qiu, Payam Kelich, Susmita Sarkar, Jiaqian Li, Kleinberg X. Fernandez, Edgar R. Alvizo-Paez, Jiayuan Miao, Shiva Kalhor-Monfared, J. Dwyer John, Hongsuk Kang, Hwanho Choi, John M. Nuss, John C. Vederas, Yu-Shan Lin, Matthew S. Macauley, Lela Vukovic, William C. K. Pomerantz, Ratmir Derda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71139748923945fe95b7a358e1ee3960
Autor:
Kleinberg X. Fernandez, Stanley Pokorny, Guncha Ishangulyeva, Aziz Ullah, Silvia I. Todorova, Nadir Erbilgin, Allan L. Carroll, John C. Vederas
Publikováno v:
Applied Microbiology and Biotechnology. 107:3341-3352
Publikováno v:
Food Microbiology. 111:104211
Autor:
Kleinberg X Fernandez, Wang Wang, Catherine Llorens-Cortes, Samantha Gottschalk, Gavin Y. Oudit, Xavier Iturrioz, Conrad Fischer, Mahmoud Gheblawi, John C. Vederas, Jennie Vu
Publikováno v:
RSC Med Chem
High blood pressure and consequential cardiovascular diseases are among the top causes of death worldwide. The apelinergic (APJ) system has emerged as a promising target for the treatment of cardiovascular issues, especially prevention of ischemia re
Autor:
Tess Lamer, Cameron Pascoe, Xavier Iturrioz, Wang Wang, Mahmoud Gheblawi, Kleinberg X Fernandez, Catherine Llorens-Cortes, Gareth R. Lambkin, Gavin Y. Oudit, Conrad Fischer, John C. Vederas
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (20), pp.12073-12082. ⟨10.1021/acs.jmedchem.0c01395⟩
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (20), pp.12073-12082. ⟨10.1021/acs.jmedchem.0c01395⟩
Apelin is an important contributor to the renin-angiotensin axis, regulating cardiovascular, metabolic, and neurological functions. Apelin-17 has especially potent cardio-physiological effects but is rapidly degraded in human blood (t0.5 ∼ 4 min).