Update on the role of genetics in the onset of age-related macular degeneration

Autor: Francis PJ, Klein ML

Publikováno v: Clinical Ophthalmology, Vol 2011, Iss default, Pp 1127-1133 (2011)

Peter James Francis, Michael L KleinMacular Degeneration Center, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USAAbstract: Age-related macular degeneration (AMD), akin to other common age-related diseases, has a complex pa

Externí odkaz: https://doaj.org/article/eaef431e95384689a9ba4696999bc215

High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction (vol 112, pg 14260, 2015)

Autor: Thomaston, JL, Alfonso-Prieto, M, Woldeyes, RA, Fraser, JS, Klein, ML, Fiorin, G, DeGrado, WF

Publikováno v: Thomaston, JL; Alfonso-Prieto, M; Woldeyes, RA; Fraser, JS; Klein, ML; Fiorin, G; et al.(2016). High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction (vol 112, pg 14260, 2015). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(18), E2548-E2548. doi: 10.1073/pnas.1605322113. UCSF: Retrieved from: http://www.escholarship.org/uc/item/56m8j2h3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::145c671d467948dc1ac3c7a540ce4d73
http://www.escholarship.org/uc/item/56m8j2h3

Exploring histidine conformations in the M2 channel lumen of the influenza a virus at neutral pH via molecular simulations

Autor: Degrado, William, Dong, H, Fiorin, G, Degrado, WF, Klein, ML

Publikováno v: Degrado, William; Dong, H; Fiorin, G; Degrado, WF; & Klein, ML. (2013). Exploring histidine conformations in the M2 channel lumen of the influenza a virus at neutral pH via molecular simulations. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3gp1f7dm

The pH-regulated M2 proton channel from the influenza A virus has a His-tetrad in its transmembrane (TM) domain that is essential for proton conduction. At neutral pH, the tetrad has been observed in two distinct configurations, the "His-box" and "di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::e4fd29761c5145c6721a2cd455335305
http://www.escholarship.org/uc/item/3gp1f7dm

Ionic charge transfer effects in water, channels and enzymes

Autor: Dal Peraro, Matteo, Lamoureux, G, Ivanov, I, Raugei, Simone, Magistrato, A, Carloni, P, Klein, Ml

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______288::f94ce5b146ef85ae03c9f1d398c408b9
http://hdl.handle.net/20.500.11767/70200

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