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In Vitro and in Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin

Autor: Bagheri, Mahsa, Fens, Marcel H, Kleijn, Tony G, Capomaccio, Robin B, Mehn, Dora, Krawczyk, Przemek M, Scutigliani, Enzo M, Gurinov, Andrei, Baldus, Marc, van Kronenburg, Nicky C H, Kok, Robbert J, Heger, Michal, van Nostrum, Cornelus F, Hennink, Wim E, Afd Pharmaceutics, Sub NMR Spectroscopy, Sub Membrane Biochemistry & Biophysics, Pharmaceutics

Publikováno v: Molecular pharmaceutics, 18(3), 1247-1263. American Chemical Society
Molecular Pharmaceutics
Molecular Pharmaceutics, 18(3), 1247. American Chemical Society

Curcumin-loaded polymeric micelles composed of poly(ethylene glycol)-b-poly(N-2-benzoyloxypropyl methacrylamide) (mPEG-b-p(HPMA-Bz)) were prepared to solubilize and improve the pharmacokinetics of curcumin. Curcumin-loaded micelles were prepared by a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac8f63b86df9685f4870e64b5235caa
https://pure.amc.nl/en/publications/in-vitro-and-in-vivo-studies-on-hpmabased-polymeric-micelles-loaded-with-curcumin(92af01b1-571a-4305-9a3f-c055ee9a87c6).html

Strategies for Improving Photodynamic Therapy Through Pharmacological Modulation of the Immediate Early Stress Response.

Autor: de Klerk DJ; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.; Laboratory of Experimental Oncology, Department of Pathology, Erasmus MC, Rotterdam, The Netherlands., de Keijzer MJ; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Dias LM; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.; Faculdade de Ciências da Saúde (FCS-UBI), Universidade da Beira Interior, Covilhã, Portugal., Heemskerk J; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China., de Haan LR; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.; Laboratory of Experimental Oncology, Department of Pathology, Erasmus MC, Rotterdam, The Netherlands., Kleijn TG; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China.; Laboratory of Experimental Oncology, Department of Pathology, Erasmus MC, Rotterdam, The Netherlands., Franchi LP; Departamento de Bioquímica e Biologia Molecular, Instituto de Ciências Biológicas (ICB) 2, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil.; Faculty of Philosophy, Department of Chemistry, Center of Nanotechnology and Tissue Engineering-Photobiology and Photomedicine Research Group, Sciences, and Letters of Ribeirão Preto, University of São Paulo, São Paulo, Brazil., Heger M; Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, People's Republic of China. m.heger@jctres.com.; Laboratory of Experimental Oncology, Department of Pathology, Erasmus MC, Rotterdam, The Netherlands. m.heger@jctres.com.; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. m.heger@jctres.com.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2451, pp. 405-480.

In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin.

Autor: Bagheri M; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands., Fens MH; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands., Kleijn TG; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands.; Department of Pharmaceutics, Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, P. R. China., Capomaccio RB; European Commission, Joint Research Centre (JRC), 21027 Ispra, VA, Italy., Mehn D; European Commission, Joint Research Centre (JRC), 21027 Ispra, VA, Italy., Krawczyk PM; Department of Medical Biology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Scutigliani EM; Department of Medical Biology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Gurinov A; NMR Spectroscopy Group, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands., Baldus M; NMR Spectroscopy Group, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands., van Kronenburg NCH; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands., Kok RJ; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands., Heger M; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands.; Department of Pharmaceutics, Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, College of Medicine, Jiaxing University, Jiaxing 314001, P. R. China., van Nostrum CF; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands., Hennink WE; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3508 TB Utrecht, The Netherlands.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2021 Mar 01; Vol. 18 (3), pp. 1247-1263. Date of Electronic Publication: 2021 Jan 19.