MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction.

Autor: Walker NM; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Ibuki Y; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., McLinden AP; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Misumi K; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Mitchell DC; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Kleer GG; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Lock AM; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Vittal R; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Sonenberg N; Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada., Garner AL; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Lama VN; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2024 Aug 15.