MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction.

Autor: Walker NM; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Ibuki Y; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., McLinden AP; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Misumi K; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Mitchell DC; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Kleer GG; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Lock AM; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Vittal R; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Sonenberg N; Department of Biochemistry and McGill Cancer Center, McGill University, Montreal, Quebec, Canada., Garner AL; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Lama VN; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

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Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls.

Autor: Kruk, Dennis^1,2 (AUTHOR), Yeung, Anna C. Y.^3,4 (AUTHOR), Faiz, Alen³ (AUTHOR), ten Hacken, Nick H. T.^2,5 (AUTHOR), Timens, Wim^1,2 (AUTHOR), van Kuppevelt, Toin H.⁶ (AUTHOR), Daamen, Willeke⁶ (AUTHOR), Hof, Danique⁶ (AUTHOR), Harmsen, Martin C.¹ (AUTHOR), Rojas, Mauricio⁷ (AUTHOR), Heijink, Irene H.^1,2,5 (AUTHOR) h.i.heijink@umcg.nl

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Atypical distribution of inflammation in newly diagnosed ulcerative colitis is not rare.

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