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pro vyhledávání: '"Klebic, Ismar"'
Akademický článek
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Autor:
Widmer, Carmen A, Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane Francine, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A, Pritchard, Colin E.J., Huijbers, Ivo J, Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven
Publikováno v:
Widmer, Carmen A; Klebic, Ismar; Domanitskaya, Natalya; Decollogny, Morgane Francine; Howald, Denise; Siffert, Myriam; Essers, Paul; Nowicka, Zuzanna; Stokar-Regenscheit, Nadine; van de Ven, Marieke; de Korte-Grimmerink, Renske; Galván, José A; Pritchard, Colin E.J.; Huijbers, Ivo J; Fendler, Wojciech; Vens, Conchita; Rottenberg, Sven (2022). Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy. Cancer research communications, 2(10), pp. 1266-1281. American Association for Cancer Research 10.1158/2767-9764.CRC-22-0208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4bca7cb46348fc4075c0127d3d0efd
Autor:
Francica, Paola, Mutlu, Merve, Blomen, Vincent A, Oliveira, Catarina, Nowicka, Zuzanna, Trenner, Anika, Gerhards, Nora M, Bouwman, Peter, Stickel, Elmer, Hekkelman, Maarten L, Lingg, Lea, Klebic, Ismar, van de Ven, Marieke, de Korte-Grimmerink, Renske, Howald, Denise, Jonkers, Jos, Sartori, Alessandro A, Fendler, Wojciech, Chapman, J Ross, Brummelkamp, Thijn, Rottenberg, Sven
Publikováno v:
Franica, Paola; Mutlu, Merve; Blomen, Vincent A.; Oliveira, Catarina; Nowicka, Zuzanna; Trenner, Anika; Gerhards, Nora M.; Bouwman, Peter; Stickel, Elmer; Hekkelman, Maarten L.; Lingg, Lea; Klebic, Ismar; van den Ven, Marieke; de Korte-Grimmerink, Renske; Howald, Denise; Jonkers, Jos; Sartori, Alessandro A.; Fendler, Wojciech; Chapman, J. Ross; Brummelkamp, Thijn; ... (2020). Functional radiogenetic profiling implicates ERCC6L2 in non-homologous end joining. Cell reports, 32(8), p. 108068. Cell Press 10.1016/j.celrep.2020.108068
Cell Reports, 32(8), 108068
Cell Reports, Vol 32, Iss 8, Pp 108068-(2020)
Cell Reports, 32(8), 108068
Cell Reports, Vol 32, Iss 8, Pp 108068-(2020)
Summary: Using genome-wide radiogenetic profiling, we functionally dissect vulnerabilities of cancer cells to ionizing radiation (IR). We identify ERCC6L2 as a major determinant of IR response, together with classical DNA damage response genes and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e326fd011ac35ef74bdebb6db7847d24
https://boris.unibe.ch/146234/2/Figure1.pdf
https://boris.unibe.ch/146234/2/Figure1.pdf
Akademický článek
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Autor:
Franica, Paola, Mutlu, Merve, Blomen, Vincent A., Oliveira, Catarina, Nowicka, Zuzanna, Trenner, Anika, Gerhards, Nora M., Bouwman, Peter, Stickel, Elmer, Hekkelman, Maarten L., Lingg, Lea, Klebic, Ismar, Van Den Ven, Marieke, De Korte-Grimmerink, Renske, Howald, Denise, Jonkers, Jos, Sartori, Alessandro A., Fendler, Wojciech, Chapman, J. Ross, Brummelkamp, Thijn, Rottenberg, Sven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6678a7e60732b56d3bb6038bade9a8
Autor:
Widmer CA; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Klebic I; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.; COMPATH, Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Domanitskaya N; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Decollogny M; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Howald D; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Siffert M; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Essers P; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Nowicka Z; Department of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland., Stokar-Regenscheit N; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., van de Ven M; Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., de Korte-Grimmerink R; Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Galván JA; Translational Research Unit, Institute of Pathology, University of Bern, Bern, Switzerland., Pritchard CEJ; Mouse Clinic for Cancer and Aging Research (MCCA), Transgenic Facility, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Huijbers IJ; Mouse Clinic for Cancer and Aging Research (MCCA), Transgenic Facility, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Fendler W; Department of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland.; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Vens C; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rottenberg S; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.; Division of Molecular Pathology, The Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.; Bern Center for Precision Medicine, University of Bern, 3012 Bern, Switzerland.; Cancer Therapy Resistance Cluster, Department for BioMedical Research, University of Bern, 3012 Bern, Switzerland.
Publikováno v:
Cancer research communications [Cancer Res Commun] 2022 Oct 26; Vol. 2 (10), pp. 1266-1281.
Autor:
Francica P; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Mutlu M; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Blomen VA; Division of Biochemistry, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Oliveira C; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Nowicka Z; Department of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland., Trenner A; Institute of Molecular Cancer Research, University of Zurich, 8057 Zurich, Switzerland., Gerhards NM; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Bouwman P; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Division of Molecular Pathology, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Stickel E; Division of Biochemistry, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Hekkelman ML; Division of Biochemistry, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Lingg L; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Klebic I; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., van de Ven M; Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., de Korte-Grimmerink R; Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Howald D; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Jonkers J; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Division of Molecular Pathology, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Sartori AA; Institute of Molecular Cancer Research, University of Zurich, 8057 Zurich, Switzerland., Fendler W; Department of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Chapman JR; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Brummelkamp T; Division of Biochemistry, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Oncode Institute, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands., Rottenberg S; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland; Division of Molecular Pathology, the Netherlands Cancer Institute, 1066CX Amsterdam, the Netherlands; Bern Center for Precision Medicine, University of Bern, 3012 Bern, Switzerland. Electronic address: sven.rottenberg@vetsuisse.unibe.ch.
Publikováno v:
Cell reports [Cell Rep] 2020 Aug 25; Vol. 32 (8), pp. 108068.