Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

mRNA-based influenza vaccine expands breadth of B cell response in humans.

Autor: Matz HC; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Yu TG; Thayer School of Engineering, Dartmouth College; Hanover, NH 03755, USA., Zhou JQ; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Peyton L; Quantitative Biomedical Sciences Program, Dartmouth College; Lebanon, NH 03756, USA., Madsen A; Influenza Centre, Department of Clinical Science, University of Bergen; 5021 Bergen, Norway.; Department of Microbiology, Haukeland University Hospital, 5009 Bergen, Norway., Han F; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Horvath SC; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Dixit K; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Keplinger HK; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Strnad BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St Louis, MO 63110, USA., Hoegger MJ; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St Louis, MO 63110, USA., Middleton WD; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St Louis, MO 63110, USA., Klebert MK; Infectious Disease Clinical Research Unit, Washington University School of Medicine; St Louis, MO 63110, USA., Lin NH; Moderna, Inc.; Cambridge, MA 02142, USA., Nachbagauer R; Moderna, Inc.; Cambridge, MA 02142, USA., Paris R; Moderna, Inc.; Cambridge, MA 02142, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA., Presti RM; Infectious Disease Clinical Research Unit, Washington University School of Medicine; St Louis, MO 63110, USA.; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine; St Louis, MO 63110, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine; St. Louis, MO 63110, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine; St. Louis, MO 63110, USA., Lee J; Thayer School of Engineering, Dartmouth College; Hanover, NH 03755, USA.; Quantitative Biomedical Sciences Program, Dartmouth College; Lebanon, NH 03756, USA., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine; St. Louis, MO 63110, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine; St. Louis, MO 63110, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 13. Date of Electronic Publication: 2024 Oct 13.

Influenza vaccination stimulates maturation of the human T follicular helper cell response.

Autor: Schattgen SA; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Ghonim MA; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Crawford JC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Kim H; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhou JQ; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Awad W; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Mettelman RC; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Kim W; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Microbiology, Korea University College of Medicine, Seoul, Korea., McIntire KM; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Haile A; Clinical Trials Unit, Washington University School of Medicine, St. Louis, MO, USA., Klebert MK; Clinical Trials Unit, Washington University School of Medicine, St. Louis, MO, USA., Suessen T; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Middleton WD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Teefey SA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Presti RM; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. ellebedy@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA. ellebedy@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA. ellebedy@wustl.edu., Thomas PG; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA. paul.thomas@stjude.org.

Publikováno v: Nature immunology [Nat Immunol] 2024 Sep; Vol. 25 (9), pp. 1742-1753. Date of Electronic Publication: 2024 Aug 20.

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.

Autor: Alsoussi WB; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Malladi SK; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Zhou JQ; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA., Ying B; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA., Kim W; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Lei T; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Horvath SC; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Sturtz AJ; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., McIntire KM; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Evavold B; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Han F; Department of Emergency Medicine, Washington University School of Medicine, St Louis, MO, USA., Scheaffer SM; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA., Fox IF; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Mirza SF; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Parra-Rodriguez L; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA., Nachbagauer R; Moderna, Cambridge, MA, USA., Nestorova B; Moderna, Cambridge, MA, USA., Chalkias S; Moderna, Cambridge, MA, USA., Farnsworth CW; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Klebert MK; Infectious Disease Clinical Research Unit, Washington University School of Medicine, St Louis, MO, USA., Pusic I; Division of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Strnad BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA., Middleton WD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA., Teefey SA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA., Diamond MS; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, MO, USA., Paris R; Moderna, Cambridge, MA, USA., O'Halloran JA; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA.; Infectious Disease Clinical Research Unit, Washington University School of Medicine, St Louis, MO, USA., Presti RM; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, USA.; Infectious Disease Clinical Research Unit, Washington University School of Medicine, St Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, MO, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. turner.j@wustl.edu., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. ellebedy@wustl.edu.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St Louis, MO, USA. ellebedy@wustl.edu.; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, MO, USA. ellebedy@wustl.edu.

Publikováno v: Nature [Nature] 2023 May; Vol. 617 (7961), pp. 592-598. Date of Electronic Publication: 2023 Apr 03.

SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.

Autor: Alsoussi WB; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; These authors contributed equally to this work., Malladi SK; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; These authors contributed equally to this work., Zhou JQ; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; These authors contributed equally to this work., Liu Z; Department of Molecular Microbiology, Washington University School of Medicine; St. Louis, MO, USA.; These authors contributed equally to this work., Ying B; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine; St. Louis, MO, USA.; These authors contributed equally to this work., Kim W; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Lei T; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Horvath SC; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Sturtz AJ; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., McIntire KM; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Evavold B; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Han F; Department of Emergency Medicine, Washington University School of Medicine; St. Louis, MO, USA., Scheaffer SM; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine; St. Louis, MO, USA., Fox IF; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Parra-Rodriguez L; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine; St. Louis, MO, USA., Nachbagauer R; Moderna, Inc.; Cambridge, MA, USA., Nestorova B; Moderna, Inc.; Cambridge, MA, USA., Chalkias S; Moderna, Inc.; Cambridge, MA, USA., Farnsworth CW; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Klebert MK; Infectious Disease Clinical Research Unit, Washington University School of Medicine; St. Louis, MO, USA., Pusic I; Division of Oncology, Department of Medicine, Washington University School of Medicine; St. Louis, MO, USA., Strnad BS; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, MO, USA., Middleton WD; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, MO, USA., Teefey SA; Mallinckrodt Institute of Radiology, Washington University School of Medicine; St. Louis, MO, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine; St. Louis, MO, USA., Diamond MS; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; Department of Molecular Microbiology, Washington University School of Medicine; St. Louis, MO, USA.; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine; St. Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine; St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine; St. Louis, MO, USA., Paris R; Moderna, Inc.; Cambridge, MA, USA., O'Halloran JA; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine; St. Louis, MO, USA.; Infectious Disease Clinical Research Unit, Washington University School of Medicine; St. Louis, MO, USA., Presti RM; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine; St. Louis, MO, USA.; Infectious Disease Clinical Research Unit, Washington University School of Medicine; St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine; St. Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine; St. Louis, MO, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO, USA.; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine; St. Louis, MO, USA.; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine; St. Louis, MO, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2022 Sep 22. Date of Electronic Publication: 2022 Sep 22.