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pro vyhledávání: '"Klavs R Hansen"'
H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases.
Autor:
Klavs R Hansen, Idit Hazan, Sreenath Shanker, Stephen Watt, Janne Verhein-Hansen, Jürg Bähler, Robert A Martienssen, Janet F Partridge, Amikam Cohen, Geneviève Thon
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001268 (2011)
Nucleosomes in heterochromatic regions bear histone modifications that distinguish them from euchromatic nucleosomes. Among those, histone H3 lysine 9 methylation (H3K9me) and hypoacetylation have been evolutionarily conserved and are found in both m
Externí odkaz:
https://doaj.org/article/a670cdb460fd4b668806fc392be4176a
Publikováno v:
Nucleic Acids Research
In Schizosaccharomyces pombe the RNAi machinery and proteins mediating heterochromatin formation regulate the transcription of non-coding centromeric repeats. These repeats share a high sequence similarity with telomere-linked helicase (tlh) genes, i
Autor:
Geneviève Thon, Gavin Burns, Juan Mata, Jürg Bähler, Robert A. Martienssen, Tom Volpe, Klavs R. Hansen
Publikováno v:
Molecular and Cellular Biology. 25:590-601
Histone modifications influence gene expression in complex ways. The RNA interference (RNAi) machinery can repress transcription by recruiting histone-modifying enzymes to chromatin, although it is not clear whether this is a general mechanism for ge
Autor:
Jenna Pfiffner, Manolis Kellis, Jonathan M. Goldberg, Hironori Niki, Hanah Margalit, Sean M. Sykes, Michael Fitzgerald, Courtney French, Brian J. Haas, Ryan J. Yoder, Lin Fan, Peter Swoboda, David C. Baulcombe, Yabin Guo, Matthew W. Vaughn, Janet Leatherwood, Carolin A. Müller, Agata Smialowska, Keita Aoki, Barbara Robbertse, Sharvari Gujja, Bruce W. Birren, Joshua Z. Levin, Rebecca A. Mosher, Naomi Habib, Sonya Vengrova, Edward Dobbs, Robert A. Martienssen, David I. Heiman, Karl Ekwall, William Brown, Ilan Wapinski, Jacob Z. Dalgaard, Sushmita Roy, Livio Dukaj, Aviv Regev, Carsten Russ, Moran Yassour, Margaret Priest, Chad Nusbaum, Qiandong Zeng, Christopher A. Desjardins, Elizabeth H. Bayne, Kanji Furuya, Huei Mei Chen, Aaron M. Berlin, Alison L. Pidoux, Henry L. Levin, Peter Baumann, Zehua Chen, Dawn Thompson, Conrad A. Nieduszynski, Robin C. Allshire, Klavs R. Hansen, Daniel Keifenheim, Michael F. Lin, Nicholas Rhind, Nir Friedman, Joseph W. Spatafora, Sarah Young
Publikováno v:
Rhind, N, Chen, Z, Yassour, M, Thompson, D A, Haas, B J, Habib, N, Wapinski, I, Roy, S, Lin, M F, Heiman, D I, Young, S K, Furuya, K, Guo, Y, Pidoux, A, Chen, H M, Robbertse, B, Goldberg, J M, Aoki, K, Bayne, E H, Berlin, A M, Desjardins, C A, Dobbs, E, Dukaj, L, Fan, L, FitzGerald, M G, French, C, Gujja, S, Hansen, K, Keifenheim, D, Levin, J Z, Mosher, R A, Mueller, C A, Pfiffner, J, Priest, M, Russ, C, Smialowska, A, Swoboda, P, Sykes, S M, Vaughn, M, Vengrova, S, Yoder, R, Zeng, Q, Allshire, R, Baulcombe, D, Birren, B W, Brown, W, Ekwall, K, Kellis, M, Leatherwood, J, Levin, H, Margalit, H, Martienssen, R, Nieduszynski, C A, Spatafora, J W, Friedman, N, Dalgaard, J Z, Baumann, P, Niki, H, Regev, A & Nusbaum, C 2011, ' Comparative Functional Genomics of the Fission Yeasts ', Science, vol. 332, no. 6032, pp. 930-936 . https://doi.org/10.1126/science.1203357
The fission yeast clade-comprising Schizosaccharomyces pombe, S. octosporus, S. cryophilus, and S. japonicus-occupies the basal branch of Ascomycete fungi and is an important model of eukaryote biology. A comparative annotation of these genomes ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d509aa1a29c380a8a809f9f1eee3a1a7
https://www.pure.ed.ac.uk/ws/files/7507857/NIH_2011_Allshire.pdf
https://www.pure.ed.ac.uk/ws/files/7507857/NIH_2011_Allshire.pdf
Autor:
Geneviève Thon, Robert A. Martienssen, Jürg Bähler, Klavs R. Hansen, Janne Verhein-Hansen, Stephen Watt, Amikam Cohen, Idit Hazan, Janet F. Partridge, Sreenath Shanker
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001268 (2011)
Hansen, K R, Hazan, I, Shanker, S, Watt, S, Hansen, J V, Bähler, J, Martienssen, R A, Partridge, J F, Cohen, A & Thon, G 2011, ' H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases ', P L o S Genetics, vol. 7, no. 1 . https://doi.org/10.1371/journal.pgen.1001268
PLOS GENET, 7 (1), Article e1001268. (2011)
PLoS Genetics
Hansen, K R, Hazan, I, Shanker, S, Watt, S, Hansen, J V, Bähler, J, Martienssen, R A, Partridge, J F, Cohen, A & Thon, G 2011, ' H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases ', P L o S Genetics, vol. 7, no. 1 . https://doi.org/10.1371/journal.pgen.1001268
PLOS GENET, 7 (1), Article e1001268. (2011)
PLoS Genetics
Nucleosomes in heterochromatic regions bear histone modifications that distinguish them from euchromatic nucleosomes. Among those, histone H3 lysine 9 methylation (H3K9me) and hypoacetylation have been evolutionarily conserved and are found in both m
Autor:
Klavs R. Hansen, Gurjeet Singh, Geneviève Thon, Deepak Sidhu, Amar J. S. Klar, Michael J. Bonaduce, Susagna Padrissa Altes, Janne Verhein-Hansen
Publikováno v:
Genetics. 171(4)
Fission yeast heterochromatin is formed at centromeres, telomeres, and in the mating-type region where it mediates the transcriptional silencing of the mat2-P and mat3-M donor loci and the directionality of mating-type switching. We conducted a genet