Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Klaus-Ulrich Weithmann"'
Autor:
Hans Matter, Wilfried Schwab, Günter Dr. Billen, Theo Wollmann, Werner Thorwart, Denis Barbier, Bernhard Neises, Haase Burkhard, Klaus-Ulrich Weithmann, Manfred Schudok
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:3529-3544
The design, synthesis and structure–activity relationship (SAR) of a series of nonpeptidic 2-arylsulfonyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylates and-hydroxamates as inhibitors of the matrix metalloproteinase human neutrophil collagenase (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612e49f25b2f0e72f8cbd834e87d6112
https://doi.org/10.1016/s0968-0896(02)00215-8
https://doi.org/10.1016/s0968-0896(02)00215-8
Autor:
Klaus Ulrich Weithmann, Norbert Ulbrich, Hansjörg Kolkenbrock, Dagmar Orgel, Werner Schröder, Adelheid Hecker-Kia
Publikováno v:
cclm. 36:697-702
Membrane binding of urokinase type plasminogen activator (u-PA) is thought to play a pivotal role in connective tissue remodeling and invasive processes. We compare the ability of different matrix-metalloproteinases involved in connective tissue turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8bbaf7d3f82558730c26d0e226efbc
https://doi.org/10.1515/cclm.1998.123
https://doi.org/10.1515/cclm.1998.123
Autor:
Sandra Schimanski, K. Ulrich Wendt, Klaus Ulrich Weithmann, Otmar Klingler, Jörg Habermann, Volkhard Schlotte, Reinhard Kirsch, Bernard Pirard, Engel Christian
Publikováno v:
Chemistrybiology. 12(2)
SummaryInhibitors for matrix metalloproteinases (MMPs) are under investigation for the treatment of cancer, arthritis, and cardiovascular disease. Here, we report a class of highly selective MMP-13 inhibitors (pyrimidine dicarboxamides) that exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bc34b35e480d240ed2435982019e97
https://pubmed.ncbi.nlm.nih.gov/15734640
https://pubmed.ncbi.nlm.nih.gov/15734640
Autor:
Klaus Ulrich Weithmann, Dieter Ruppert
Publikováno v:
Life Sciences. 31:2037-2043
The new pyrimido-isoquinoline compound HL 725 is an extremely potent inhibitor of the aggregation of human platelets induced in vitro by ADP, collagen, thrombin and epinephrine. The aggregation induced by 0,5 mM arachidonic acid is inhibited about 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbff580d8d5b8ba7a1d4f9cea8b1f66
https://doi.org/10.1016/0024-3205(82)90095-9
https://doi.org/10.1016/0024-3205(82)90095-9