Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Klaus-Peter Janßen"'
Autor:
Maximilian Hohmann, Valentina Brunner, Widya Johannes, Dominik Schum, Laura M. Carroll, Tianzhe Liu, Daisuke Sasaki, Johanna Bosch, Thomas Clavel, Stephan A. Sieber, Georg Zeller, Markus Tschurtschenthaler, Klaus-Peter Janßen, Tobias A. M. Gulder
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The gut microbiota influences human health and the development of chronic diseases. However, our understanding of potentially protective or harmful microbe-host interactions at the molecular level is still in its infancy. To gain further ins
Externí odkaz:
https://doaj.org/article/9dfc486a3c544c3f8858b03305338c9f
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/d802b0ec3bbf4f4ea854b3c2c4ce73f7
Autor:
Anurag Kumar Singh, Amrita Rai, Anja Weber, Martin Gericke, Klaus-Peter Janssen, Markus Moser, Guido Posern
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-16 (2023)
Abstract The actin-regulated transcription factor MRTF-A represents a central relay in mechanotransduction and controls a subset of SRF-dependent target genes. However, gain-of-function studies in vivo are lacking. Here we characterize a conditional
Externí odkaz:
https://doaj.org/article/ef11d5185015412c903701ddcf0ad2a8
Autor:
Tanja Krauss, Simone Heisz, Julius Honecker, Olga Prokopchuk, Marc Martignoni, Klaus‐Peter Janssen, Melina Claussnitzer, Hans Hauner, Claudine Seeliger
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1381-1394 (2023)
Abstract Background Cancer cachexia (CCx) is a complex and multi‐organ wasting syndrome characterized by substantial weight loss and poor prognosis. An improved understanding of the mechanisms involved in the onset and progression of cancer cachexi
Externí odkaz:
https://doaj.org/article/fa2b9d86fd734cea8f952ca7d9b532be
Autor:
Alexandra Chovsepian, Olga Prokopchuk, Gabriela Petrova, Tefta Gjini, Hanna Kuzi, Simone Heisz, Klaus-Peter Janssen, Marc E. Martignoni, Helmut Friess, Hans Hauner, Maria Rohm
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101729- (2023)
Objectives: Cancer is considered an emerging diabetes complication, with higher incidence and worse prognosis in patients with diabetes. Cancer is frequently associated with cachexia, a systemic metabolic disease causing wasting. It is currently uncl
Externí odkaz:
https://doaj.org/article/d40cb0c9c06a45978ceba0834e1c25a4
Autor:
Aladin Haimovici, Christoph Höfer, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Tarek Amer, Melanie Boerries, Peter Bronsert, Ievgen Glavynskyi, Deborah Fanfone, Gabriel Ichim, Nico Thilmany, Arnim Weber, Tilman Brummer, Corinna Spohr, Rupert Öllinger, Klaus-Peter Janssen, Roland Rad, Georg Häcker
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-14 (2022)
Abstract Micronuclei are DNA-containing structures separate from the nucleus found in cancer cells. Micronuclei are recognized by the immune sensor axis cGAS/STING, driving cancer metastasis. The mitochondrial apoptosis apparatus can be experimentall
Externí odkaz:
https://doaj.org/article/b7284db964514626a9e10ff7d8334a01
Autor:
David Schult, Sandra Reitmeier, Plamena Koyumdzhieva, Tobias Lahmer, Moritz Middelhoff, Johanna Erber, Jochen Schneider, Juliane Kager, Marina Frolova, Julia Horstmann, Lisa Fricke, Katja Steiger, Moritz Jesinghaus, Klaus-Peter Janssen, Ulrike Protzer, Klaus Neuhaus, Roland M. Schmid, Dirk Haller, Michael Quante
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
There is a growing debate about the involvement of the gut microbiome in COVID-19, although it is not conclusively understood whether the microbiome has an impact on COVID-19, or vice versa, especially as analysis of amplicon data in hospitalized pat
Externí odkaz:
https://doaj.org/article/0d64f28858eb4fdba2a6630ef6f2d6ee
Autor:
Nikole Radani, Amira Metwaly, Sandra Reitmeier, Theresa Baumeister, Jonas Ingermann, Julia Horstmann, Akanksha Anand, Ingrid Gatz, Florian Kohlmayer, Klaus-Peter Janssen, Julia Slotta-Huspenina, Roland M. Schmid, Dirk Haller, Julian A. Abrams, Michael Quante
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 5, Pp 755-766 (2022)
Background and Aims: Esophageal adenocarcinoma (EAC) incidence has risen dramatically in the Western countries over the past decades. The underlying reasons are incompletely understood, and shifts in the esophageal microbiome have been postulated to
Externí odkaz:
https://doaj.org/article/ecf22d062de1458e84dc182c4f71316e
Autor:
Krzysztof Flisikowski, Carolin Perleberg, Guanglin Niu, Thomas Winogrodzki, Agnieszka Bak, Wei Liang, Alessandro Grodziecki, Yue Zhang, Hubert Pausch, Tatiana Flisikowska, Bernhard Klinger, Anna Perkowska, Alexander Kind, Marek Switonski, Klaus-Peter Janssen, Dieter Saur, Angelika Schnieke
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 669-671.e3 (2022)
Externí odkaz:
https://doaj.org/article/77d8d73d088d4e66b4ca02860f3b3c5b
Autor:
Thomas Kunzke, Achim Buck, Verena M. Prade, Annette Feuchtinger, Olga Prokopchuk, Marc E. Martignoni, Simone Heisz, Hans Hauner, Klaus‐Peter Janssen, Axel Walch, Michaela Aichler
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 226-240 (2020)
Abstract Background Cachexia is the direct cause of at least 20% of cancer‐associated deaths. Muscle wasting in skeletal muscle results in weakness, immobility, and death secondary to impaired respiratory muscle function. Muscle proteins are massiv
Externí odkaz:
https://doaj.org/article/0ec20947e9fd46489b26afa082368a23