Zobrazeno 1 - 10
of 1 193
pro vyhledávání: '"Klaus-Michael Debatin"'
Autor:
Teresa Mack, Tommaso Gianferri, Alexandra Niedermayer, Klaus-Michael Debatin, Lüder H. Meyer, Vera Muench
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract MicroRNAs (miRNAs) play dual roles in acute lymphoblastic leukemia (ALL) as both tumor suppressors and oncogenes, and miRNA expression profiles can be used for patient risk stratification. Precise assessment of miRNA levels is crucial for un
Externí odkaz:
https://doaj.org/article/14c79f1c61ac4ce2b6503afde094d609
Autor:
Stefanie Enzenmüller, Alexandra Niedermayer, Felix Seyfried, Vera Muench, Daniel Tews, Ulrich Rupp, Eugen Tausch, Alexander Groß, Pamela Fischer-Posovszky, Paul Walther, Stephan Stilgenbauer, Hans A. Kestler, Klaus-Michael Debatin, Lüder Hinrich Meyer
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-14 (2024)
Abstract Deregulated apoptosis signaling is characteristic for many cancers and contributes to leukemogenesis and treatment failure in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Apoptosis is controlled by different pro- and anti-apoptot
Externí odkaz:
https://doaj.org/article/81d58ab860b9478bbf43ea3ace525546
Autor:
Julian Roos, Julia Zinngrebe, Markus Huber-Lang, Ludmila Lupu, Miriam A. Schmidt, Hannah Strobel, Mike-Andrew Westhoff, Ulrich Stifel, Florian Gebhard, Martin Wabitsch, Tom Eirik Mollnes, Klaus-Michael Debatin, Rebecca Halbgebauer, Pamela Fischer-Posovszky
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-12 (2024)
Abstract Despite advances in the treatment and care of severe physical injuries, trauma remains one of the main reasons for disability-adjusted life years worldwide. Trauma patients often suffer from disturbances in energy utilization and metabolic d
Externí odkaz:
https://doaj.org/article/9f52a16066934815b7ce2e2190f13169
Autor:
Celimene Galiger, Fatema Tuj Zohora, Carmen Dorneburg, Daniel Tews, Klaus-Michael Debatin, Christian Beltinger
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Neuroblastoma (NB), the most common extracranial solid malignancy in children, carries a poor prognosis in high-risk disease, thus requiring novel therapeutic approaches. Survivin is overexpressed in NB, has pro-mitotic and anti-a
Externí odkaz:
https://doaj.org/article/9100e93ebbf64044b94b9b9d6f5cd5c6
Autor:
Erika Ongemach, Daniela Zerrinius, Philipp Heimann, Christian Rainer Wirtz, Klaus-Michael Debatin, Mike-Andrew Westhoff, Aurelia Peraud
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 401 (2024)
Glioblastoma, the most common and lethal primary adult brain tumor, cannot be successfully removed surgically due to its highly invasive nature. Therapeutically, approaches must be aimed at a systemic brain disease and not merely at a tumor located w
Externí odkaz:
https://doaj.org/article/559534186fec4f25bc5438a9bd934562
Autor:
Helge Hebestreit, Anne-Marie Lapstich, Lilly Brandstetter, Christian Krauth, Jürgen Deckert, Kirsten Haas, Lisa Pfister, Stefanie Witt, Christopher Schippers, Jan Dieris-Hirche, Tim Maisch, Oliver Tüscher, Lavinia Bârlescu, Alexandra Berger, Mark Berneburg, Vanessa Britz, Anna Deibele, Holm Graeßner, Harald Gündel, Gereon Heuft, Thomas Lücke, Christine Mundlos, Julia Quitmann, Frank Rutsch, Katharina Schubert, Jörg Bernhard Schulz, Susann Schweiger, Cornelia Zeidler, Lena Zeltner, Martina de Zwaan, Federica Akkaya, Christine Babka, Lisa Bannert, Anja Bärsch-Michelmann, Leonie Böhm, Folke Brinkmann, Monika Bullinger, Holger Cario, Moritz de Greck, Klaus-Michael Debatin, Katrin Dillmann-Jehn, Jutta Eymann, Julia Frisch, Anja Glode, Vega Gödecke, Corinna Grasemann, Eva Grauer, Astrid Haas, Lea Haisch, Isabell, Heinrich, Melissa Held, Julia Hennermann, Stephan Herpertz, Anne Herrmann-Werner, Julian Hett, Peter Heuschmann, Bettina Hilbig, Laura Holthöfer, Christiane Imhof, Florian Junne, Jan Kassubek, Kevin-Thomas Koschitzki, Heike Krassort, Birgit Kropff, Julia Kuhn, Philipp Latzko, Thomas Loew, Albert C. Ludolph, Torsten Meyer, Isabell Meyer dos Santos, Klaus Mohnike, Martina Monninger, Martin Mücke, Susanne Müller, Thomas Musacchio, Margret Nießen, Mariel Nöhre, Stephan Ott, Andrea Petermann-Meyer, Christina Pfeifer-Duck, Lea-Sophie Piduhn, Carina Rampp, Olaf Rieß, Kristina Schaubert, Annika Schmidt, Simone Schneider, Ludger Schoels, Martina Schwalba, Udo Selig, Alexandra Sroka, Toni Steinbüchel, Sebastian Stösser, Steffi Suchant, Kathrin Ungethüm, Matthias Vogel, Daniela Volk, Christoph Vollmuth, Solange Volnov, Thomas O.F. Wagner, Sabrina Walter, Bodo Warrings, Kamil Zajt, Karola Zenker, David Zhang, Stephan Zipfel, Lavinia Aurelia Bârlescu, Julia Hannah Quitmann, Jörg B. Schulz, Lena Margarete Zeltner
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102260- (2023)
Summary: Background: People with complex symptomatology but unclear diagnosis presenting to a centre for rare diseases (CRD) may present with mental (co-)morbidity. We hypothesised that combining an expert in somatic medicine with a mental health spe
Externí odkaz:
https://doaj.org/article/7104fbd316dd40be90da99c4bb8c26c0
Autor:
Eva-Maria Jacobsen, Dorit Fabricius, Magdalena Class, Fernando Topfstedt, Raquel Lorenzetti, Iga Janowska, Franziska Schmidt, Julian Staniek, Maria Zernickel, Thomas Stamminger, Andrea N. Dietz, Angela Zellmer, Manuel Hecht, Peter Rauch, Carmen Blum, Carolin Ludwig, Bernd Jahrsdörfer, Hubert Schrezenmeier, Maximilian Heeg, Benjamin Mayer, Alina Seidel, Rüdiger Groß, Jan Münch, Frank Kirchhoff, Sebastian F. N. Bode, Gudrun Strauss, Hanna Renk, Roland Elling, Maximillian Stich, Reinhard E. Voll, Burkhard Tönshof, Axel R. Franz, Philipp Henneke, Klaus-Michael Debatin, Marta Rizzi, Ales Janda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Severity of SARS-CoV-2 infection is different in adults and children which involves the immune response. Here using a parent and children cohort with 4 month and 12 month sampling times, the authors show enhanced levels and increased breadth of anti-
Externí odkaz:
https://doaj.org/article/81ce609da88b45238e8d4a923e4304a2
Autor:
Qian Sun, Piotr Zabrocki, Felix Seyfried, Hans de Haard, Geertruyte Kronnie, Klaus-Michael Debatin, Lüder Hinrich Meyer
Publikováno v:
HemaSphere, Vol 7, p e6339407 (2023)
Externí odkaz:
https://doaj.org/article/a01f7d008f9e4da7bbade35e2c308a7b
Autor:
Alina Seidel, Eva-Maria Jacobsen, Dorit Fabricius, Magdalena Class, Maria Zernickel, Carmen Blum, Carina Conzelmann, Tatjana Weil, Rüdiger Groß, Sebastian F. N. Bode, Hanna Renk, Roland Elling, Maximillian Stich, Frank Kirchhoff, Klaus-Michael Debatin, Jan Münch, Aleš Janda
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionDurability of immune protection against reinfection with SARS-CoV-2 remains enigmatic, especially in the pediatric population and in the context of immune-evading variants of concern. Obviously, this knowledge is required for measures to
Externí odkaz:
https://doaj.org/article/bc8842172d6a4f71844ef10e1613a2d4
Autor:
Pengfei Xu, Mike-Andrew Westhoff, Amina Hadzalic, Klaus-Michael Debatin, Lukasz Winiarski, Jozef Oleksyszyn, Christian Rainer Wirtz, Uwe Knippschild, Timo Burster
Publikováno v:
ACS Omega, Vol 7, Iss 7, Pp 5929-5936 (2022)
Externí odkaz:
https://doaj.org/article/8054992f457a40bb980f1b248e750204