Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Klaus-Dieter Spindler"'
Autor:
Garima Jain, Cornelia Voogdt, Anna Tobias, Klaus-Dieter Spindler, Peter Möller, Marcus V. Cronauer, Ralf B. Marienfeld
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 3, Pp 178-189 (2012)
Enhanced nuclear localization of nuclear factor κB (NF-κB) in prostate cancer (PCa) samples and constitutive NF-κB signaling in a class of PCa cell lines with low androgen receptor (AR) expression (PC3 and DU-145) imply an important role of the I
Externí odkaz:
https://doaj.org/article/e9c39e4629ad489dbcbb99e4813b4f22
Autor:
Ludwig Rinnab, Stefanie V. Schütz, Jeannine Diesch, Evi Schmid, Rainer Küfer, Richard E. Hautmann, Klaus-Dieter Spindler, Marcus V. Cronauer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 6, Pp 624-633 (2008)
The glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase widely expressed in mammalian tissues. Ini-tially identified by its ability to modulate glycogen synthesis, GSK-3 turned out to be a multifunctional enzyme, able to phosphorylate man
Externí odkaz:
https://doaj.org/article/e23f9fbd0ba147b7aa59458c5bed1a53
Autor:
Michael R. Reich, Timo Burster, Hubert Kalbacher, Klaus-Dieter Spindler, Bernhard O. Boehm, Michael Burret
Publikováno v:
Immunology Letters. 128:143-147
Cathepsins are expressed in antigen-presenting cells (APC). These cathepsins are known to regulate antigen processing and degradation of the invariant chain (Ii) into the class II-associated Ii peptide (CLIP), which occupies the peptide-binding groov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9523ca9bc0d3126eb553812518f16660
https://doi.org/10.1016/j.imlet.2009.11.010
https://doi.org/10.1016/j.imlet.2009.11.010
Publikováno v:
Archives of Insect Biochemistry and Physiology. 68:40-48
Initially, nuclear import of the ecdysteroid receptor (EcR) in vertebrate cells (CHO-K1 and COS-7) does not afford a heterodimerization partner. Later on, EcR is retained in the nucleus only in the presence of a heterodimerization partner. Ultraspira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc7cada611ff2a895a55e8bbd03ebf3
https://doi.org/10.1002/arch.20234
https://doi.org/10.1002/arch.20234
Publikováno v:
Cellular Signalling. 19:2582-2587
In the absence of hormone the ecdysteroid receptor (EcR) is distributed between the cytoplasm and the nucleus. Addition of the hormone muristerone A increases nuclear localization of wild type EcR within 5-10 min. Mutation of M504 to alanine, an amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77458f1468b846f0383ee19a2fb8fb3
https://doi.org/10.1016/j.cellsig.2007.08.007
https://doi.org/10.1016/j.cellsig.2007.08.007
Publikováno v:
Entomologia Generalis. 27:257-268
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ecfd62c507de1cc221f98e89c46fe6
https://doi.org/10.1127/entom.gen/27/2005/257
https://doi.org/10.1127/entom.gen/27/2005/257
Publikováno v:
Synthesis. :1543-1549
Analogs of naturally occurring furanones that were reported to be weak inhibitors of Serratia marcescens chitinases were prepared and tested towards various chitinases. Some of these compounds - but not the natural products - were found to be weak bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e70a6fe68969252c90ed25fdac02c96
https://doi.org/10.1055/s-2005-865356
https://doi.org/10.1055/s-2005-865356
Autor:
Klaus-Dieter Spindler, Anya Salih, Jörg Wiedenmann, Florian Schmitt, G. Ulrich Nienhaus, Carlheinz Röcker, Franz Oswald, Sergey Ivanchenko
Publikováno v:
Proceedings of the National Academy of Sciences. 101:15905-15910
A gene encoding a fluorescent protein from the stony coral Lobophyllia hemprichii has been cloned in Escherichia coli and characterized by biochemical and biophysical methods. The protein, which we named EosFP, emits strong green fluorescence (516 nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0355378b4108565aa4f9c26127b98e
https://doi.org/10.1073/pnas.0403668101
https://doi.org/10.1073/pnas.0403668101
Autor:
B.S. Schuett, Wolfgang Weidemann, Gabriela Romalo, Martin W. Elmlinger, Michael B. Ranke, D. Diesing, H.U. Schweikert, Klaus-Dieter Spindler
Publikováno v:
Hormone Research in Paediatrics. 60:73-78
Background: We investigated the effects of androgens, estradiol (E2) and insulin-like growth factor (IGF)-I on IGF-II, insulin-like growth factor binding protein (IGFBP)-2, -3 and -5 and mRNA in genital fibroblasts (GF) from patients with complete an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5dcca52d2de1c620933b27ddc98126
https://doi.org/10.1159/000071874
https://doi.org/10.1159/000071874