Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Klaus-Detlev Schultz"'
Publikováno v:
Clinical & Experimental Allergy. 27:1322-1327
Summary Background Bradykinin, a potent inflammatory mediator, is released during allergic and non-allergic rhinitis and asthma in man. Nasal bradykinin challenge induces a dose-dependent plasma leakage into the nasal cavity and relevant symptoms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb340a8418f4feabdf0dfb7fdbb0c43
https://doi.org/10.1111/j.1365-2222.1997.tb01178.x
https://doi.org/10.1111/j.1365-2222.1997.tb01178.x
Autor:
Klaus Detlev Schultz, M Böttcher, M Schmidt, G. Kunkel, J. Furkert, Claus R. Baumgarten, A O'Connor
Publikováno v:
Neuropeptides. 30:117-124
The determination of substance P (SP) concentrations in human nasal lavages can be used to monitor physiological and certain pathophysiological processes in human airway mucosa. But, because of the low concentrations, immunoassays of high sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b6e82a19f29b464b671cde6b8b4d80
https://doi.org/10.1016/s0143-4179(96)90078-5
https://doi.org/10.1016/s0143-4179(96)90078-5
Autor:
Sandra Biroc, Gert Kunkel, Michael Gräfe, Minzhong Zhang, Kristof Graf, Eckart Fleck, Christian Schudt, Kerstin Kunkel, Klaus Detlev Schultz
Publikováno v:
Peptides. 16:1273-1278
Endothelial neutral endopeptidase (EC 3.4.24.11, NEP) contributes to the inactivation of vasoactive and inflammatory peptides such as f-Met-Leu-Phe, substance P, atrial natriuretic peptide, and bradykinin. The aim of the present study was to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321d400a3a1d32f25daca6364aee83ff
https://doi.org/10.1016/0196-9781(95)00077-w
https://doi.org/10.1016/0196-9781(95)00077-w
Autor:
Thomas Schnellbacher, Cathrine Lucas, Klaus Detlev Schultz, Claus R. Baumgarten, Kristof Graf, Gert Kunkel, Jochen Niehus, Silke Müller, Minzhong Zhang
Publikováno v:
Peptides. 15:843-848
We describe the development of a new ELISA for the detection of neural endopeptidase 3.4.24.11 (NEP). Neutral endopeptidase 3.4.24.11 was determined in preparations of human granulocytes, mononuclear cells (MNC), and in serum. Human recombinant NEP w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b4e4efbc6ac824e4e11d8807be731d
https://doi.org/10.1016/0196-9781(94)90040-x
https://doi.org/10.1016/0196-9781(94)90040-x
Publikováno v:
International archives of allergy and immunology. 107(1-3)
There is growing evidence that substance P (SP) is one of the main neuropeptides involved in neurogenic inflammation of the airways. However, a number of studies were not able to demonstrate histamine release from human mucosal mast cells after SP ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cc2f8627cddda8ef86b375c19a0ed1
https://pubmed.ncbi.nlm.nih.gov/7542055
https://pubmed.ncbi.nlm.nih.gov/7542055
Autor:
Klaus Detlev Schultz, Katrin Schierhorn, Parwis Agha-Mir-Salim, Tilo Brunnée, Gert Kunkel, Jochen Niehus, Ralf Paus
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 31(3)
Considerable progress has recently been made in the understanding of airway inflammation by cell culture assays and in vivo provocation studies. Inasmuch as ethical considerations limit experimental work in humans, physiologically relevant in vitro m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721ba21fdba990d029bb41145e64ea64
https://pubmed.ncbi.nlm.nih.gov/7538857
https://pubmed.ncbi.nlm.nih.gov/7538857
Autor:
H M Thiede, Markus Rothschild, Klaus-Detlev Schultz, Andreas Kribben, Armin Distler, E Fritschka, Thomas Philipp
Publikováno v:
Journal of Hypertension. 7:S48-49
The regulation of platelet alpha 2- and lymphocyte beta 2-adrenoceptor densities by alterations in endogenous catecholamines was examined. In order to activate the sympathetic nervous system eight trained male normotensive subjects carried out a mara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::604b7c66cf28bcae49b40435dc36a09e
https://doi.org/10.1097/00004872-198900076-00021
https://doi.org/10.1097/00004872-198900076-00021
Publikováno v:
Journal of Hypertension. 7:S142-143
Since a significant heritability has been shown for forskolin stimulation of lymphocyte adenylate cyclase activity in twins, we evaluated lymphocyte forskolin-stimulated adenylate cyclase activity with respect to a familial predisposition towards ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdaefaa347308c4c205e201ffa44644
https://doi.org/10.1097/00004872-198900076-00067
https://doi.org/10.1097/00004872-198900076-00067