Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Klaus von der Mark"'
Autor:
Clara-Sophie Kossel, Mandy Wahlbuhl, Sonia Schuepbach-Mallepell, Jung Park, Christine Kowalczyk-Quintas, Michaela Seeling, Klaus von der Mark, Pascal Schneider, Holm Schneider
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
X-linked hypohidrotic ectodermal dysplasia with the cardinal symptoms hypodontia, hypotrichosis and hypohidrosis is caused by a genetic deficiency of ectodysplasin A1 (EDA1). Prenatal EDA1 replacement can rescue the development of skin appendages and
Externí odkaz:
https://doaj.org/article/29f8c79279b345aaa0a27af1af43f8d9
Autor:
Xin Qin, Qing Jiang, Kenichi Nagano, Takeshi Moriishi, Toshihiro Miyazaki, Hisato Komori, Kosei Ito, Klaus von der Mark, Chiharu Sakane, Hitomi Kaneko, Toshihisa Komori
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009169 (2020)
Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteobl
Externí odkaz:
https://doaj.org/article/dc0c4288b3134efd9fe3a25ef2562db1
Autor:
Jung Park, Matthias Gebhardt, Svitlana Golovchenko, Francesc Perez-Branguli, Takako Hattori, Christine Hartmann, Xin Zhou, Benoit deCrombrugghe, Michael Stock, Holm Schneider, Klaus von der Mark
Publikováno v:
Biology Open, Vol 4, Iss 5, Pp 608-621 (2015)
According to the general understanding, the chondrocyte lineage terminates with the elimination of late hypertrophic cells by apoptosis in the growth plate. However, recent cell tracking studies have shown that murine hypertrophic chondrocytes can su
Externí odkaz:
https://doaj.org/article/e2798622190b474cb08d9c471dbfacbb
Autor:
Xin Zhou, Klaus von der Mark, Stephen Henry, William Norton, Henry Adams, Benoit de Crombrugghe
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004820 (2014)
One of the crucial steps in endochondral bone formation is the replacement of a cartilage matrix produced by chondrocytes with bone trabeculae made by osteoblasts. However, the precise sources of osteoblasts responsible for trabecular bone formation
Externí odkaz:
https://doaj.org/article/65b058aec78d436bba860b8e0ebc3baa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1867:748-756
Fibulin-4 is a 50 kDa glycoprotein of elastic fibers and plays an important role in development and function of elastic tissues. Fibulin-4 consists of a tandem array of five calcium-binding epidermal growth factor-like modules flanked by N- and C-ter
Autor:
Mukta Kulkarni, Anca Mazare, Slavko Kralj, Ekaterina Gongadze, Patrik Schmuki, Jung Park, Manuela S. Killian, Aleš Iglič, Klaus von der Mark
Publikováno v:
Acta Biomaterialia. 45:357-366
In the present work we investigate the key factors involved in the interaction of small-sized charged proteins with TiO 2 nanostructures, i.e. albumin (negatively charged), histone (positively charged). We examine anodic nanotubes with specific morph
Autor:
Ursula Schlötzer-Schrehardt, Takako Sasaki, Takao Sakai, Mon-Li Chu, Klaus von der Mark, Andreas Hess, Rainer Deutzmann, Reinout Stoop
Publikováno v:
Matrix Biology. 50:53-66
The extracellular matrix protein fibulin-4 has been shown to be indispensable for elastic fiber assembly, but there is also evidence from human mutations that it is involved in controlling skeletal development and bone stability. Fibulin-4 mutations
Autor:
Hisato Komori, Qing Jiang, Klaus von der Mark, Hitomi Kaneko, Kosei Ito, Toshihiro Miyazaki, Kenichi Nagano, Chiharu Sakane, Xin Qin, Toshihisa Komori, Takeshi Moriishi
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009169 (2020)
PLoS Genetics
PLoS Genetics
Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteobl
Autor:
Irute Girkontaite, Jon Oberdorf, William A. Horton, Chelsea S. Bahney, Jeremie Larouche, Klaus von der Mark, Bruce A. Boston, Sarah M. Almubarak, Michael D. Aiona, Ryan F. Coghlan, Daniel Coleman, Susan Sienko, Gregory P. Lunstrum, Kara J. Connelly
Publikováno v:
Science Translational Medicine
Despite its importance as a key parameter of child health and development, growth velocity is difficult to determine in real time because skeletal growth is slow and clinical tools to accurately detect very small increments of growth do not exist. We