Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Klaus Ziereis"'
Publikováno v:
Planta Medica. 64:536-540
The ethanolic extract of Ilex aquifolium L. (Aquifoliaceae) concentration-dependently inhibited leukotriene B4 biosynthesis in isolated bovine PMNL with an IC50 value of about 60 micrograms/ml, whereas the effect on epidermal 12(S)-HETE biosynthesis
Autor:
Klaus Müller, Klaus Ziereis
Publikováno v:
Planta Medica. 60:421-424
The effects of the extract of the bark of Mahonia aquifolium and its main constituents (berberine, berbamine, oxyacanthine) on 5-lipoxygenase, lipid peroxidation in phospholipid liposomes induced by 2,2'-azo-(bis-2-amidinopropane), deoxyribose degrad
Publikováno v:
Journal of Medicinal Chemistry. 37:1660-1669
A novel series of 2- and 3-substituted 1,8-dihydroxy-9(10H)-anthracenones were synthesized and tested for their inhibitory activity against 5-lipoxygenase (5-LO) in bovine polymorphonuclear leukocytes and the growth of human keratinocytes. Structure-
Autor:
Klaus Müller, Klaus Ziereis
Publikováno v:
Archiv der Pharmazie. 325:219-223
The syntheses of endoperoxides of naphthalene derivatives with propionic acid and ethanesulfonic acid side chains are described. The partition coefficients and half-lives for the thermal decomposition in phosphate buffer of all compounds have been de
Autor:
Klaus Müller, Klaus Ziereis
Publikováno v:
Archiv der Pharmazie. 326:369-371
The utility of dimethyl 3,3′-(4-methyl-1,3-naphthylene)dipropionate (DMNDP) as a singlet oxygen trap in biological systems is described. The determination of the rate constant for the reaction of DMNDP with singlet oxygen in acetonitrile gave a val
Publikováno v:
Journal of ethnopharmacology. 70(3)
The methanolic extracts of 25 different Nepalese medicinal plants were tested for their activity to inhibit the biosynthesis of leukotriene B(4) in bovine polymorphonuclear leukocytes. The selected indigenous plants are used in traditional herb remed
Publikováno v:
Journal of medicinal chemistry. 40(23)
Fifty-nine simple analogues of the antipsoriatic agent, anthralin, have been prepared by modifying the positions of the 1,8-hydroxyl groups, replacement of the hydroxyl groups, substitution at the oxygen functions, introduction of additional function
Autor:
Klaus Müller, Klaus Ziereis
Publikováno v:
Archiv der Pharmazie. 326(10)
Inhibition of 5-lipoxygenase from bovine polymorphonuclear leukocytes and 12-lipoxygenase from bovine platelets by active oxygen species has been studied. Oxygen radicals and hydrogen peroxide markedly inhibited 12-lipoxygenase, whereas 5-lipoxygenas
Publikováno v:
Planta Medica. 61:74-75
The extract of the bark of Mahonia aquifolium is an inhibitor of keratinocyte growth with an IC50 of 35 microM. Of its main alkaloids tested, berberine inhibited cell growth to the same extent as did the Mahonia extract, while the benzylisoquinoline
Publikováno v:
Monatshefte fuer Chemie/Chemical Monthly. 130:713