Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Klaus Wethmar"'
Autor:
Inna Shaforostova, Simon Call, Georg Evers, Christian Reicherts, Linus Angenendt, Matthias Stelljes, Wolfgang E. Berdel, Alexander Pohlmann, Jan‐Henrik Mikesch, Frank Rosenbauer, Georg Lenz, Christoph Schliemann, Klaus Wethmar
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 93-104 (2024)
Abstract Flow cytometry‐based immunophenotyping is a mainstay of diagnostics in acute myeloid leukaemia (AML). Aberrant CD56 and T‐cell antigen expression is observed in a fraction subset of AML cases, but the clinical relevance remains incomplet
Externí odkaz:
https://doaj.org/article/88331a79d0454531ba11c14b63ff48ce
Autor:
Carolin Krekeler, Klaus Wethmar, Jan-Henrik Mikesch, Andrea Kerkhoff, Kerstin Menck, Georg Lenz, Hans-Ulrich Schildhaus, Michael Wessolly, Matthias W. Hoffmann, Andreas Pascher, Inga Asmus, Eva Wardelmann, Annalen Bleckmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12056 (2023)
DNA mismatch repair deficient (dMMR) and microsatellite instable (MSI) metastatic colorectal cancer (mCRC) can be successfully treated with FDA- and EMA-approved immune checkpoint inhibitors (ICI) pembrolizumab and nivolumab (as single agents targeti
Externí odkaz:
https://doaj.org/article/d54ab952bd2342a491d0c232b97b1a54
Autor:
Lara Jürgens, Klaus Wethmar
Publikováno v:
Cancers, Vol 14, Iss 24, p 6031 (2022)
Recent technological advances have facilitated the detection of numerous non-canonical human peptides derived from regulatory regions of mRNAs, long non-coding RNAs, and other cryptic transcripts. In this review, we first give an overview of the clas
Externí odkaz:
https://doaj.org/article/a48690ecd9e04ca8984fb7d9cac9e9b9
Autor:
Daniela V. Wenge, Klaus Wethmar, Corinna A. Klar, Hedwig Kolve, Tim Sauer, Linus Angenendt, Georg Evers, Simon Call, Andrea Kerkhoff, Cyrus Khandanpour, Torsten Kessler, Rolf Mesters, Christoph Schliemann, Jan-Henrik Mikesch, Christian Reicherts, Monika Brüggemann, Wolfgang E. Berdel, Georg Lenz, Matthias Stelljes
Publikováno v:
Cancers, Vol 14, Iss 3, p 565 (2022)
Prognosis of elderly ALL patients remains dismal. Here, we retrospectively analyzed the course of 93 patients > 55 years with B-precursor (n = 88) or T-ALL (n = 5), who received age-adapted, pediatric-inspired chemotherapy regimens at our center betw
Externí odkaz:
https://doaj.org/article/46ad73a271064086af31255825cf3446
Autor:
Lara Jürgens, Felix Manske, Elvira Hubert, Tabea Kischka, Lea Flötotto, Oliver Klaas, Victoria Shabardina, Christoph Schliemann, Wojciech Makalowski, Klaus Wethmar
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 618 (2021)
Upstream open reading frame (uORF)-mediated translational control has emerged as an important regulatory mechanism in human health and disease. However, a systematic search for cancer-associated somatic uORF mutations has not been performed. Here, we
Externí odkaz:
https://doaj.org/article/51576d248f9c4c60b0ae57c9e59e687b
Autor:
Julia Schulz, Nancy Mah, Martin Neuenschwander, Tabea Kischka, Richard Ratei, Peter M. Schlag, Esmeralda Castaños-Vélez, Iduna Fichtner, Per-Ulf Tunn, Carsten Denkert, Oliver Klaas, Wolfgang E. Berdel, Jens P. von Kries, Wojciech Makalowski, Miguel A. Andrade-Navarro, Achim Leutz, Klaus Wethmar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/9b12c72f34034452bb7c35bb98c9b263
Autor:
Felix Manske, Lynn Ogoniak, Lara Jürgens, Norbert Grundmann, Wojciech Makałowski, Klaus Wethmar
Publikováno v:
Nucleic Acids Research. 51:D328-D336
Upstream open reading frames (uORFs) are initiated by AUG or near-cognate start codons and have been identified in the transcript leader sequences of the majority of eukaryotic transcripts. Functionally, uORFs are implicated in downstream translation
Autor:
Michaela Kotrová, Johannes Koopmann, Heiko Trautmann, Nael Alakel, Joachim Beck, Kathrin Nachtkamp, Björn Steffen, Simon Raffel, Andreas Viardot, Klaus Wethmar, Nikos Darzentas, Claudia D. Baldus, Nicola Gökbuget, Monika Brüggemann
Publikováno v:
Blood Advances. 6:3006-3010
Persistence of minimal residual disease (MRD) after induction/consolidation therapy in acute lymphoblastic leukemia is the leading cause of relapse. The GMALL 07/2003 study used MRD detection by real-time quantitative polymerase chain reaction of clo
Autor:
Klaus Wethmar, Lara Jürgens
Recent technological advances have facilitated the detection of numerous non-canonical human peptides derived from regulatory regions of mRNAs, long non-coding RNAs, and other cryptic transcripts. In this review, we first give an overview of the clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a36c632f7713056c47ee288716ed573
https://repositorium.uni-muenster.de/transfer/miami/9a246c98-941f-457e-9ed7-c0b47cad0b3b
https://repositorium.uni-muenster.de/transfer/miami/9a246c98-941f-457e-9ed7-c0b47cad0b3b
Autor:
Norbert Schmitz, Sarah Bergmann, Klaus Wethmar, Rolf M. Mesters, Torsten Keßler, Matthias Stelljes, Wolfgang E. Berdel, Georg Lenz, Ramona Wullenkord, Christoph Schliemann, Mathias Lutz, Philipp Berning, Anna-Lena Niemann
Publikováno v:
Annals of Hematology
Patients with high-risk or relapsed aggressive B-cell lymphomas are characterized by poor prognosis. High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) can induce durable remissions in these patients and is potentially cur