Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Klaus Resch"'
Autor:
Anneke Doerrie, Juliane von der Ohe, Latifa Bakiri, Erwin F. Wagner, Klaus Resch, Elke Hoffmann, Axel Weber, Michael Kracht, Heike Schneider, Sabine Wolter
Publikováno v:
Wolter, S, Doerrie, A, Weber, A, Schneider, H, Hoffmann, E, von der Ohe, J, Bakiri, L, Wagner, E F, Resch, K & Kracht, M 2008, ' c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene ', Molecular and Cellular Biology, vol. 28, no. 13, pp. 4407-23 . https://doi.org/10.1128/MCB.00535-07
Udgivelsesdato: 2008-Jul Interleukin-1 (IL-1)-induced mRNA expression of ccl2 (also called MCP-1), a prototypic highly regulated inflammatory gene, is severely suppressed in cells lacking c-Jun or Jun N-terminal protein kinase 1 (JNK1)/JNK2 genes and
Autor:
Myriam Bartels, Aike Torben Schweda, W. Beil, Ursula Dreikhausen, Ronald Frank, Mahtab Nourbakhsh, Klaus Resch
Publikováno v:
The Journal of Immunology. 179:7605-7613
Selective inhibition of proinflammatory chemokines such as IL-8 is an important approach to combat inflammatory and infection diseases. Previous studies suggested that interaction of transcription factors NFκB repressing factor (NRF) and NFκB play
Publikováno v:
Biochemical and Biophysical Research Communications. 354:1089-1094
Ligand binding in the Toll-like/interleukin-1 receptor family results in the recruitment of an intracellular signaling complex. IRAK-1, which is centrally involved in this complex, is able to homo-oligomerize and to bind to Tollip and the adapters My
Autor:
Detlef Neumann, Klaus Resch
Publikováno v:
Encyclopedia of Immunotoxicology ISBN: 9783642277863
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeec3e0415b04946982b6ee5925bc593
https://doi.org/10.1007/978-3-642-54596-2_341
https://doi.org/10.1007/978-3-642-54596-2_341
Autor:
Sascha Rother, Klaus Resch, Myriam Bartels, Aike Torben Schweda, Mahtab Nourbakhsh, Norbert Pallua
Publikováno v:
The FASEB journal 30(1), 174-185 (2016). doi:10.1096/fj.15-270256
NF-κB-repressing factor (NKRF) inhibits transcription elongation by binding to specific sequences in target promoters. Stimuli such as IL-1 have been shown to overcome this inhibitory action and enable the resumption of transcription elongation mach
Autor:
Andreas Schmiedl, Daniela Popa, Guillermo Pérez de Lema, Klaus Resch, Thomas Tschernig, Detlef Neumann, Michael U. Martin
Publikováno v:
International Immunology. 18:1779-1787
IL-12 and IL-18 are mediators involved in the onset and progression of the autoimmune disease developing in MRL/Mp-Tnfrsf6(lpr) (lpr) mice, which display symptoms similar to the human systemic lupus erythematosus (SLE). The pathology is characterized
Autor:
Alexander Wolf, Hiroaki Sakurai, Axel Thiefes, Rainer Niedenthal, Michael Kracht, Kunihiro Matsumoto, Ingo B. Autenrieth, Erwin Bohn, Klaus Resch, Anneke Doerrie, Guntram A. Grassl
Publikováno v:
EMBO reports. 7:838-844
The mechanism by which YopP simultaneously inhibits mitogen-activated protein kinase (MAPK) and nuclear factor-kappaB pathways has been elusive. Ectopic expression of YopP inhibits the activity and ubiquitination of a complex consisting of overexpres
Publikováno v:
Clinica Chimica Acta. 364:239-245
Background Ertapenem (Invanz®) is a newly developed carbapenem β-lactam antibiotic. LC–MS is the method of choice for therapeutic drug monitoring (TDM) of a variety of drugs including antibiotics. No validated LC–MS method for ertapenem quantif
Autor:
Sabine Wolter, Michael Kracht, Axel Thiefes, Elke Hoffmann, Heike Schneider, J. Frederic Mushinski, Nadine Graue, Klaus Resch, Dagmar Wirth, Oliver Dittrich-Breiholz, Bruno Luckow, Anneke Dörrie
Publikováno v:
Journal of Biological Chemistry. 280:27728-27741
The inflammatory response is characterized by the induction (or repression) of hundreds of genes. The activity of many of these genes is controlled by MAPKs and the IkappaB kinase-NFkappaB pathway. To reveal the effects of blocking these pathways sim
Autor:
Klaus Resch, Volkhard Kaever
Publikováno v:
Pharmazie in unserer Zeit. 34:268-275
Die Umwelt, in der wir leben, enthalt zu allen Zeiten Noxen – Gifte, Infektionserreger – die zu schwerer Krankheit und Tod fuhren konnen. Ohne die Moglichkeit, diese uber das Immunsystem abzuwehren, konnte niemand uberleben. Allerdings gibt es au