Zobrazeno 1 - 10
of 150 485
pro vyhledávání: '"Klaus P"'
Autor:
Sophie F. Warken, Dana F. C. Riechelmann, Jens Fohlmeister, Andrea Schröder-Ritzrau, Norbert Frank, Denis Scholz, Klaus P. Jochum, Ionuț-Cornel Mirea, Silviu Constantin, Christoph Spötl
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-13 (2024)
Abstract The response of European precipitation variability to climate change is still poorly understood. Here we present a high-resolution speleothem record of Eastern Central European (ECE) autumn/winter precipitation to study decadal to centennial
Externí odkaz:
https://doaj.org/article/25a3532b07a74f31ac111362bc0c0c51
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is frequently detected in late stages, which leads to limited therapeutic options and a dismal overall survival rate. To date, no robust method for the detection of early-stage PDAC that can be used fo
Externí odkaz:
https://doaj.org/article/b8847a40687f44c1b4bcf77ba0ffe9bd
Autor:
Nikolay Tonchev, Anatoli Pinchuk, Claudia A. Dumitru, Belal Neyazi, Vanessa Magdalena Swiatek, Klaus Peter Stein, Ibrahim Erol Sandalcioglu, Ali Rashidi
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4599-4612 (2024)
Cranial operations are associated with a high risk of postoperative intracranial hemorrhage (pICH) and venous thromboembolic events, along with increased mortality and morbidity. With the use of acetylsalicylic acid (ASA) for prophylaxis becoming mor
Externí odkaz:
https://doaj.org/article/b47267e8573f416e81d99ca5f742b645
Autor:
Judith Lind, Osman Aksoy, Michaela Prchal-Murphy, Fengjuan Fan, Mariateresa Fulciniti, Dagmar Stoiber, Latifa Bakiri, Erwin F. Wagner, Elisabeth Zwickl-Traxler, Martin Sattler, Karoline Kollmann, Sonia Vallet, Klaus Podar
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Deregulation of transcription factors (TFs) leading to uncontrolled proliferation of tumor cells within the microenvironment represents a hallmark of cancer. However, the biological and clinical impact of transcriptional interference, partic
Externí odkaz:
https://doaj.org/article/6f0fada8d8aa46c2a07a49b9d5a5c9ab
Autor:
Eriselda Mino, Klaus Pfeifer, Coral L. Hanson, Michael Schuler, Anna Brandmeier, Sarah Klamroth, Inga Naber, Anja Weissenfels, Sheona McHale, Karim Abu-Omar, Peter Gelius, Stephen Whiting, Kremlin Wickramasinghe, Gauden Galea, Wolfgang Geidl
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Physical activity referral schemes (PARS) are composed of various components, such as a written prescription or a person-centered approach. The role of these components in their effectiveness is yet to be understood. Therefore, we
Externí odkaz:
https://doaj.org/article/f9737f51426e4f24945592e9ad21762b
Autor:
Mohammadhossein Kardan, Andres Jung, Mehvish Iqbal, Saeed Keshtkar, Wolfgang Geidl, Klaus Pfeifer
Publikováno v:
BMC Digital Health, Vol 2, Iss 1, Pp 1-15 (2024)
Abstract Background Physical inactivity is considered one of the main modifiable risk factors for noncommunicable diseases. It has been proven that an active lifestyle is an efficient means of preventing and managing noncommunicable diseases. Multipl
Externí odkaz:
https://doaj.org/article/78be5f735ec144a098e3d00d30cbf3df
Autor:
Sebastian A. Fuchs, Lisanna Hülse, Teresa Tamayo, Susanne Kolbe-Busch, Klaus Pfeffer, Alexander T. Dilthey
Publikováno v:
mSystems, Vol 9, Iss 11 (2024)
ABSTRACT Genomic surveillance enables the early detection of pathogen transmission in healthcare facilities and contributes to the reduction of substantial patient harm. Fast turnaround times, flexible multiplexing, and low capital requirements make
Externí odkaz:
https://doaj.org/article/4f958f28a1de4ecca2b94725eae96dbd
Autor:
Daniel J. Smit, Konstantin Hoffer, Bettina Bettin, Malte Kriegs, Laure Cayrefourcq, Udo Schumacher, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker
Publikováno v:
Cancer Medicine, Vol 13, Iss 20, Pp n/a-n/a (2024)
ABSTRACT Background Research on circulating tumor cells (CTCs) offers the opportunity to better understand the initial steps of blood‐borne metastasis as main cause of cancer‐related deaths. Here, we have used the colon cancer CTC‐MCC‐41 and
Externí odkaz:
https://doaj.org/article/01c855f9ce71411bbeb5e216d4700d46
Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma
Autor:
Mark Sementsov, Leonie Ott, Julian Kött, Alexander Sartori, Amelie Lusque, Sarah Degenhardt, Bertille Segier, Isabel Heidrich, Beate Volkmer, Rüdiger Greinert, Peter Mohr, Ronald Simon, Julia-Christina Stadler, Darryl Irwin, Claudia Koch, Antje Andreas, Benjamin Deitert, Verena Thewes, Andreas Trumpp, Andreas Schneeweiss, Yassine Belloum, Sven Peine, Harriett Wikman, Sabine Riethdorf, Stefan W Schneider, Christoffer Gebhardt, Klaus Pantel, Laura Keller
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1560-1578 (2024)
Abstract Circulating tumor DNA (ctDNA) is the cornerstone of liquid biopsy diagnostics, revealing clinically relevant genomic aberrations from blood of cancer patients. Genomic analysis of single circulating tumor cells (CTCs) could provide additiona
Externí odkaz:
https://doaj.org/article/4b6305c88a944631907935568207306e
Autor:
Nishit Goradia, Stefan Werner, Edukondalu Mullapudi, Sarah Greimeier, Lina Bergmann, Andras Lang, Haydyn Mertens, Aleksandra Węglarz, Simon Sander, Grzegorz Chojnowski, Harriet Wikman, Oliver Ohlenschläger, Gunhild von Amsberg, Klaus Pantel, Matthias Wilmanns
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characterization, investigation of these mechanisms in disordered proteins is more challenging due to the
Externí odkaz:
https://doaj.org/article/5074a5174b144e20817298b0df93967f