Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Klaus Neuhaus"'
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Analysis of genome wide transcription start sites (TSSs) revealed an unexpected complexity since not only canonical TSS of annotated genes are recognized by RNA polymerase. Non-canonical TSS were detected antisense to, or within, annotated g
Externí odkaz:
https://doaj.org/article/f510639c8a714ebf8328cac2ebb88923
Autor:
Laura Joachim, Sascha Göttert, Anna Sax, Katja Steiger, Klaus Neuhaus, Paul Heinrich, Kaiji Fan, Erik Thiele Orberg, Karin Kleigrewe, Jürgen Ruland, Florian Bassermann, Wolfgang Herr, Christian Posch, Simon Heidegger, Hendrik Poeck
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104834- (2023)
Summary: Background: Inter-individual differences in response to immune checkpoint inhibitors (ICI) remain a major challenge in cancer treatment. The composition of the gut microbiome has been associated with differential ICI outcome, but the underly
Externí odkaz:
https://doaj.org/article/12cd81f05fce4a928aea82b9ae65b9a3
Autor:
Ann-Kathrin Joerger, Carolin Albrecht, Veit Rothhammer, Klaus Neuhaus, Arthur Wagner, Bernhard Meyer, Maria Wostrack
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 48 (2023)
In recent years, there has been a growing interest in the role of the microbiome in cardiovascular and cerebrovascular diseases. Emerging research highlights the potential role of the microbiome in intracranial aneurysm (IA) formation and rupture, pa
Externí odkaz:
https://doaj.org/article/b8a484aa7e964e208a8e3eb01f09ac21
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Current methods of high-throughput RNA sequencing of prokaryotes, including transcriptome analysis or ribosomal profiling, need deep sequencing to achieve sufficient numbers of effective reads (e.g., mapping to mRNA) in order to also find we
Externí odkaz:
https://doaj.org/article/d85b100d4a1e417a825a7ad6eb2aee40
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The abundance of long overlapping genes in prokaryotic genomes is likely to be significantly underestimated. To date, only a few examples of such genes are fully established. Using RNA sequencing and ribosome profiling, we found expression o
Externí odkaz:
https://doaj.org/article/a433a119bb7b48bc91202fe9ec9dc259
Autor:
David Schult, Sandra Reitmeier, Plamena Koyumdzhieva, Tobias Lahmer, Moritz Middelhoff, Johanna Erber, Jochen Schneider, Juliane Kager, Marina Frolova, Julia Horstmann, Lisa Fricke, Katja Steiger, Moritz Jesinghaus, Klaus-Peter Janssen, Ulrike Protzer, Klaus Neuhaus, Roland M. Schmid, Dirk Haller, Michael Quante
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
There is a growing debate about the involvement of the gut microbiome in COVID-19, although it is not conclusively understood whether the microbiome has an impact on COVID-19, or vice versa, especially as analysis of amplicon data in hospitalized pat
Externí odkaz:
https://doaj.org/article/0d64f28858eb4fdba2a6630ef6f2d6ee
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background One limiting factor of short amplicon 16S rRNA gene sequencing approaches is the use of low DNA amounts in the amplicon generation step. Especially for low-biomass samples, insufficient or even commonly undetectable DNA amounts ca
Externí odkaz:
https://doaj.org/article/06df479deb10444a9714f74b4607114e
Autor:
Hannes Hoelz, Jeannine Heetmeyer, Anastasia Tsakmaklis, Andreas Hiergeist, Kolja Siebert, Federica De Zen, Deborah Häcker, Amira Metwaly, Klaus Neuhaus, André Gessner, Maria J. G. T. Vehreschild, Dirk Haller, Tobias Schwerd
Publikováno v:
Nutrients, Vol 15, Iss 7, p 1742 (2023)
Background: Exclusive enteral nutrition (EEN) is a highly effective therapy for remission induction in pediatric Crohn’s disease (CD), but relapse rates after return to a regular diet are high. Autologous fecal microbiota transfer (FMT) using stool
Externí odkaz:
https://doaj.org/article/761e8bbe7a05439c8d12927988537837
Autor:
Yacine Amar, Ilias Lagkouvardos, Rafaela L. Silva, Oluwaseun Ayodeji Ishola, Bärbel U. Foesel, Susanne Kublik, Anne Schöler, Sebastian Niedermeier, Rachela Bleuel, Alexander Zink, Klaus Neuhaus, Michael Schloter, Tilo Biedermann, Martin Köberle
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background The identification of microbiota based on next-generation sequencing (NGS) of extracted DNA has drastically improved our understanding of the role of microbial communities in health and disease. However, DNA-based microbiome analy
Externí odkaz:
https://doaj.org/article/096945f250a7470dacd9952e35693ff8
Publikováno v:
Animal Microbiome, Vol 3, Iss 1, Pp 1-17 (2021)
Abstract Background Little is known about the complex interactions between the diet, the gut microbiota, and enteropathogens. Here, the impact of two specific diets on the composition of the mouse gut microbiota and on the transcriptional response of
Externí odkaz:
https://doaj.org/article/0c3ba0bfd49a4073bce6d7024419d408