Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Klaus Leibe"'
Programmable high voltage CMOS chips for particle-based high-density combinatorial peptide synthesis
Autor:
Frank Breitling, Felix Löffler, Alexander Nesterov, U. Trunk, F. Painke, Thomas Felgenhauer, Ines Block, Kai König, Klaus Leibe, Gloria Torralba, Simon Fernandez, Volker Stadler, Volker Lindenstruth, Christopher Schirwitz, F. R. Bischoff, Michael Hausmann, J. Wagner
Publikováno v:
Sensors and Actuators B: Chemical
Sensors and Actuators B: Chemical; Vol 147
Sensors and Actuators B: Chemical; Vol 147
We built high voltage complementary metal oxide semiconductor (CMOS) chips that generate electrical fields on their surface, such that electrically charged microparticles (diameter 10–20 μm on average) can be addressed on distinct pixel electrodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0ec37b4a7c79b3f620660fcef38e0b
Autor:
Gloria Torralba, Martin Gröning, Stefan Güttler, Volker Lindenstruth, F. Ralf Bischoff, Thomas Felgenhauer, Ines Block, Volker Stadler, Michael Hausmann, Simon Fernandez, Kai König, Klaus Leibe, Mario Beyer, Alexander Nesterov, Frank Breitling, Annemarie Poustka, Rüdiger Pipkorn
Publikováno v:
Angewandte Chemie International Edition. 47:7132-7135
however, thedecodingofpeptidebindersislaborintensive.Furthermore,problematicpeptides,forexample,hydrophobicpeptidesthatbind nonspecifically to any protein, are also synthesizedduringlibrarypreparationbythesemethods.Arrays do not have these drawbacks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144adb6c2aff317e5f5d21784bbb4e9a
https://doi.org/10.1002/anie.200801616
https://doi.org/10.1002/anie.200801616
Autor:
Michael Hausmann, Mario Beyer, Rüdiger Pipkorn, Volker Stadler, F. Ralf Bischoff, Frank Breitling, Kai König, Martin Gröning, Simon Fernandez, Klaus Leibe, Ines Block, Stefan Güttler, Annemarie Poustka, Gloria Torralba, Volker Lindenstruth, Alexander Nesterov, Thomas Felgenhauer
Publikováno v:
Angewandte Chemie. 120:7241-7244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0495889f488d1bd1b2df8e237f09fc3a
https://doi.org/10.1002/ange.200801616
https://doi.org/10.1002/ange.200801616
Autor:
Stefan Güttler, Martin Gröning, Peter Willems, Bernd Biesinger, Frank Breitling, Ralf Bischoff, Volker Stadler, Thomas Felgenhauer, Klaus Leibe, Simon Fernandez
Publikováno v:
NIP & Digital Fabrication Conference. 24:471-475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d1505ed4b23c8af20206c1cdbdc525
https://doi.org/10.2352/issn.2169-4451.2008.24.1.art00004_2
https://doi.org/10.2352/issn.2169-4451.2008.24.1.art00004_2
Autor:
Volker Lindenstruth, Klaus Leibe, Alexander Nesterov, Kai König, Frank Breitling, Thomas Felgenhauer, Felix Löffler, Volker Stadler, F. R. Bischoff, Michael Hausmann, U. Trunk
Publikováno v:
Journal of Physics D: Applied Physics. 40:6115-6120
We present a method based on induced currents in a cylindrical probe which allows analysis of the micro-particle charging processes in an aerosol. The micro particles were triboelectrically charged by passing through a dielectric tube coaxially mount
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::333a263725ab46e452b8f08a1c093770
https://doi.org/10.1088/0022-3727/40/19/053
https://doi.org/10.1088/0022-3727/40/19/053
Autor:
Gloria Torralba, Frank Breitling, Kai König, Simon Fernandez, Ines Block, Volker Stadler, Klaus Leibe, F. Ralf Bischoff, Thomas Felgenhauer, Alexander Nesterov, Michael Hausmann, Christopher Schirwitz, Volker Lindenstruth
Publikováno v:
Current Protocols in Protein Science
Microchips are used in the combinatorial synthesis of peptide arrays by means of amino acid microparticle deposition. The surface of custom-built microchips can be equipped with an amino-modified poly(ethylene glycol)methacrylate (PEGMA) graft polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b6c6dda9698e607e64054a5f831e84
https://pubmed.ncbi.nlm.nih.gov/19688736
https://pubmed.ncbi.nlm.nih.gov/19688736
Autor:
Mario, Beyer, Ines, Block, Kai, König, Alexander, Nesterov, Simon, Fernandez, Thomas, Felgenhauer, Christopher, Schirwitz, Klaus, Leibe, Ralf F, Bischoff, Frank, Breitling, Volker, Stadler
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 570
Combinatorial synthesis of peptides on solid supports (1), either as spots on cellulose membranes (2) or with split-pool-libraries on polymer beads (3), substantially forwarded research in the field of peptide-protein interactions. Admittedly, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fed673fa019f7d97eb062ba81d0ec1ba
https://pubmed.ncbi.nlm.nih.gov/19649602
https://pubmed.ncbi.nlm.nih.gov/19649602
Autor:
Thomas Felgenhauer, Alexander Nesterov, Simon Fernandez, Ines Block, Mario Beyer, Klaus Leibe, Christopher Schirwitz, Frank Breitling, Volker Stadler, Kai König, Ralf Bischoff
Publikováno v:
Peptide Microarrays ISBN: 9781603273930
Combinatorial synthesis of peptides on solid supports (1), either as spots on cellulose membranes (2) or with split-pool-libraries on polymer beads (3), substantially forwarded research in the field of peptide-protein interactions. Admittedly, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317a05cdc97ba0db36eb248a1594e173
https://doi.org/10.1007/978-1-60327-394-7_16
https://doi.org/10.1007/978-1-60327-394-7_16
Autor:
Frank Breitling, Michael Hausmann, Volker Lindenstruth, Volker Stadler, Felix Löffler, Ralf Bischoff, Alexander Nesterov, Klaus Leibe, Thomas Felgenhauer, U. Trunk, Kai König
Publikováno v:
The Review of scientific instruments. 78(7)
In this study examples for a noncontact procedure that allow the description of instant electric charging of moving microparticles that contact dielectric surfaces, for instance, of a flow hose are presented. The described principle is based on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5151522af1b7341ec499db69c9db09c4
https://pubmed.ncbi.nlm.nih.gov/17672797
https://pubmed.ncbi.nlm.nih.gov/17672797
Autor:
Frank Breitling, Volker Stadler, Simon Fernandez, Kai König, F. Ralf Bischoff, Mario Beyer, Ines Block, Thomas Felgenhauer, Klaus Leibe, U. Trunk, Alexander Nesterov, Gloria Torralba, Volker Lindenstruth, Michael Hausmann
Publikováno v:
Science. 318:1888-1888
Arrays promise to advance biology through parallel screening for binding partners. We show the combinatorial in situ synthesis of 40,000 peptide spots per square centimeter on a microchip. Our variant Merrifield synthesis immobilizes activated amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23311c900088fd3c986d914fdf68975
https://doi.org/10.1126/science.1149751
https://doi.org/10.1126/science.1149751