Zobrazeno 1 - 10
of 396
pro vyhledávání: '"Klaus Kopka"'
Autor:
Santiago Andrés Brühlmann, Martin Walther, Magdalena Kerstin Blei, Constantin Mamat, Klaus Kopka, Robert Freudenberg, Martin Kreller
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-22 (2024)
Abstract Background In recent years, targeted alpha therapy has gained importance in the clinics, and in particular, the alpha-emitter 225Ac plays a fundamental role in this clinical development. Nevertheless, depending on the chelating system no rea
Externí odkaz:
https://doaj.org/article/77ffd4f08c9b45cc8d911bdb6fedb0e9
Autor:
Aurélie Maisonial-Besset, David Kryza, Klaus Kopka, Sophie Levesque, Emmanuel Moreau, Barbara Wenzel, Jean-Michel Chezal
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-22 (2024)
Abstract Background (S)-[18F]FETrp is a promising PET radiotracer for imaging IDO1 activity, one of the main enzymes involved in the tryptophan metabolism that plays a key role in several diseases including cancers. To date, the radiosynthesis of thi
Externí odkaz:
https://doaj.org/article/49b3c42351434cc394f2ac1f88f2ef8f
Autor:
Robert Wodtke, Markus Laube, Sandra Hauser, Sebastian Meister, Friedrich-Alexander Ludwig, Steffen Fischer, Klaus Kopka, Jens Pietzsch, Reik Löser
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-25 (2024)
Abstract Background Transglutaminase 2 (TGase 2) is a multifunctional protein and has a prominent role in various (patho)physiological processes. In particular, its transamidase activity, which is rather latent under physiological conditions, gains i
Externí odkaz:
https://doaj.org/article/22eb1f3fd9ac49ebabcd4cbb268205c3
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Background There are only a handful of true theranostic matched pairs, and in particular the theranostic radiocopper trio 61Cu, 64Cu and 67Cu, for diagnosis and therapy respectively, is a very attractive candidate. In fact, the alternative o
Externí odkaz:
https://doaj.org/article/ed13beb721a54725a525c9fa3a2b9c64
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Background [18F]fluoromisonidazole ([18F]FMISO, 1H-1-(3-[18F]fluoro-2-hydroxypropyl)-2-nitroimidazole) is a commonly used radiotracer for imaging hypoxic conditions in cells. Since hypoxia is prevalent in solid tumors, [18F]FMISO is in clini
Externí odkaz:
https://doaj.org/article/99efab76f3f348aa9f829691c84d1b13
Publikováno v:
Instruments, Vol 8, Iss 1, p 10 (2024)
A new Center for Radiopharmaceutical Cancer Research was established at the Helmholtz-Zentrum Dresden-Rossendorf in 2017 to centralize radionuclide and radiopharmaceutical production, as well as enable chemical and biochemical research. Routine produ
Externí odkaz:
https://doaj.org/article/faa941ad03cf470da2d89f89f8d5e9c4
Autor:
Jun Toyohara, Mohammed Al-Qahtani, Ya-Yao Huang, Emiliano Cazzola, Sergio Todde, Shozo Furumoto, Renata Mikolajczak, Clemens Decristoforo, Nic Gillings, Min Yang, Raymond Reilly, Adriano Duatti, Antonia Denkova, Ralf Schirrmacher, Giuseppe Carlucci, Yann Seimbille, Zhaofei Liu, Beverley Ellis, Bart T. Cornelissen, Klaus Kopka, Emerson Bernardes
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development. Main Body This commentary of highlights has res
Externí odkaz:
https://doaj.org/article/76c90f3fe43644fe83b312ca3ccee3c0
Autor:
Matthias Miederer, Martina Benešová-Schäfer, Constantin Mamat, David Kästner, Marc Pretze, Enrico Michler, Claudia Brogsitter, Jörg Kotzerke, Klaus Kopka, David A. Scheinberg, Michael R. McDevitt
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 76 (2024)
The use of radionuclides for targeted endoradiotherapy is a rapidly growing field in oncology. In particular, the focus on the biological effects of different radiation qualities is an important factor in understanding and implementing new therapies.
Externí odkaz:
https://doaj.org/article/25291905b7a14e40b287668ad107995a
Autor:
Austin Craig, Jürgen Kogler, Markus Laube, Martin Ullrich, Cornelius K. Donat, Robert Wodtke, Klaus Kopka, Sven Stadlbauer
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2749 (2023)
Early detection and treatment of cancers can significantly increase patient prognosis and enhance the quality of life of affected patients. The emerging significance of the tumor microenvironment (TME) as a new frontier for cancer diagnosis and thera
Externí odkaz:
https://doaj.org/article/664a01d0f78c4972ad7e20ef2c2023c5
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Background Positron emission tomography (PET) is a powerful tool in medical imaging, especially in combination with the PET radionuclide fluorine-18 that possesses optimal characteristics. For labelling of biomolecules and low-molecular weig
Externí odkaz:
https://doaj.org/article/97f7218c584545b0ae6eea319188fdf8