Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Klaus Knop"'
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
The granule size distribution is a critical quality attribute of granules. It has a great impact on further packaging or processing. Due to increasing interest in continuous manufacturing techniques, it is of high interest to develop an in-line or on
Externí odkaz:
https://doaj.org/article/c72779818c064cdc985a04c3e8b986bd
Autor:
Peter Kleinebudde, Klára Pintye-Hódi, Klaus Knop, Géza Regdon, Joshua Müller, Péter Kása, Markus Wirges
Publikováno v:
Pharmaceutics, Vol 3, Iss 4, Pp 723-730 (2011)
Background: Active coating is an important unit operation in the pharmaceutical industry. The quality, stability, safety and performance of the final product largely depend on the amount and uniformity of coating applied. Active coating is challengin
Externí odkaz:
https://doaj.org/article/142841c7c54149659d1f4c75886948b6
Autor:
Tobie J. Matemb Ma Ntep, Mohammad Wahiduzzaman, Eric Laurenz, Ieuan Cornu, Georges Mouchaham, Iurii Dovgaliuk, Shyamapada Nandi, Klaus Knop, Christian Jansen, Farid Nouar, Pierre Florian, Gerrit Füldner, Guillaume Maurin, Christoph Janiak, Christian Serre
The development of thermally driven water-sorption-based technologies relies on high-performing water vapor adsorbents. Here, polymorphism in Al-metal-organic frameworks is disclosed as a new strategy to tune the hydrophilicity of MOFs. This involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540ada2d783668010a83a17c4a0d75d1
https://doi.org/10.24406/publica-1576
https://doi.org/10.24406/publica-1576
Publikováno v:
Journal of Pharmaceutical Sciences. 106:302-312
Co-amorphous drug-amino acid systems have gained growing interest as an alternative to common amorphous formulations which contain polymers as stabilizers. Several preparation methods have recently been investigated, including vibrational ball millin
Publikováno v:
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
Graphical abstract
The granule size distribution is a critical quality attribute of granules. It has a great impact on further packaging or processing. Due to increasing interest in continuous manufacturing techniques, it is of high interest to
The granule size distribution is a critical quality attribute of granules. It has a great impact on further packaging or processing. Due to increasing interest in continuous manufacturing techniques, it is of high interest to
Autor:
Andreas Altmeyer, Klaus Knop, Peter Kleinebudde, Johannes Khinast, Rok Dreu, Adrian Funke, Gregor Toschkoff
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 106:97-106
The tablet pan coating process involves various types of transverse tablet bed motions, ranging from rolling to cascading. To preserve satisfactory results in terms of coating quality after scale-up, understanding the dynamics of pan coating process
Publikováno v:
International Journal of Pharmaceutics. 499:271-279
Individual dosing of medicines is relevant for paediatrics, geriatrics and personalised medicine. The Solid Dosage Pen (SDP) allows for individual dosing by cutting monolithic, tablet-like drug carriers of pre-defined heights. The aim of the present
Autor:
Katrine Tarp Jensen, Lasse Ingerslev Blaabjerg, Thomas Rades, Korbinian Löbmann, Peter Kleinebudde, Holger Grohganz, Klaus Knop, Elisabeth Lenz
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 96:44-52
Co-amorphous drug formulations provide the possibility to stabilize a drug in its amorphous form by interactions with low molecular weight compounds, e.g. amino acids. Recent studies have shown the feasibility of spray drying as a technique to manufa
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 88:931-938
A spatial filtering velocimetry (SFV) probe was applied to monitor the increase in particle size during pellet Wurster coating processes in-line. Accuracy of the in-line obtained pellet sizes was proven by at-line performed digital image analysis (DI
Publikováno v:
International journal of pharmaceutics. 536(1)
The vulnerability of controlled release formulations when co-ingested with alcohol represents a current major concern of regulatory agencies. Dose dumping might occur when drugs and/or excipients exhibit higher solubility in ethanolic solutions compa