Zobrazeno 1 - 10
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pro vyhledávání: '"Klaus Joeris"'
Autor:
Klaus Joeris, Sven Markert
Publikováno v:
Biotechnology and Bioengineering. 114:113-121
We developed an automated microtiter plate (MTP)-based system for suspension cell culture to meet the increased demands for miniaturized high throughput applications in biopharmaceutical process development. The generic system is based on off-the-she
Publikováno v:
Biotechnology progress. 35(2)
Recently, we established an automated microtiter plate (MTP)-based system for suspension cell culture for high-throughput (HT) applications in biopharmaceutical process development. In the present report, the new system was evaluated regarding its po
Autor:
Sven, Markert, Klaus, Joeris
Publikováno v:
Biotechnology and bioengineering. 114(1)
We developed an automated microtiter plate (MTP)-based system for suspension cell culture to meet the increased demands for miniaturized high throughput applications in biopharmaceutical process development. The generic system is based on off-the-she
Publikováno v:
Biotechnology Progress. 21:1109-1118
A four-parameter logistic equation was used to fit batch and fed-batch time profiles of viable cell density in order to estimate net growth rates from the inoculation through the cell death phase. Reduced three-parameter forms were used for nutrient
Autor:
Andrew Johnson, Chetan T. Goudar, Alois Knoll, Jürgen Lehmann, Rüdiger Heidemann, Jim Michaels, Klaus Joeris, Cary Matanguihan, Thomas Scheper, Chun Zhang, Jan-Gerd Frerichs, Konstantin Konstantinov
Publikováno v:
IFAC Proceedings Volumes. 37:387-391
We have developed a framework that is capable of providing complete automation of mammalian cell perfusion processes. This framework includes an expert system that provides low-level control of the process based on data obtained from online and offli
Publikováno v:
Chemie Ingenieur Technik. 74:1629-1633
Autor:
Klaus Joeris, Thomas Scheper
Publikováno v:
Chemie Ingenieur Technik. 74:56-59
Publikováno v:
Cytotechnology. 38:129-134
The in-situ microscope is a system developed to acquire images of mammalian cells directly inside a bioreactor (in-situ) duringa fermentation process. It requires only minimal operator intervention and it is well suited for either batch or long-termp
Autor:
Klaus Joeris, Sven Markert
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 5, Iss Suppl 8, p O9 (2011)
BMC Proceedings, Vol 5, Iss Suppl 8, p O9 (2011)
The automation of cell culture processes becomes more important in the pharmaceutical industry due to compressed timelines and the need to develop more products more efficiently. This drive to develop new processes faster and more efficient requires
Publikováno v:
Biotechnology progress. 28(2)
The newly developed in situ oxygen uptake rate (in situ OUR) probe presented in this article is based on the in situ microscope technology platform. It is designed to measure the oxygen uptake rate (OUR) of mammalian cells, an important parameter for