Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Klaus Gebhardt"'
Publikováno v:
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 190(13)
Recommendations for screening crucially depend on the diagnostic and therapeutic setting. We do not agree with the authors’ statement that aldosteronism is “a relatively common cause of resistant hypertension worldwide.”[1][1] We also disagree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae632330a2348ab3e8129012053e6664
https://pubmed.ncbi.nlm.nih.gov/28584041
https://pubmed.ncbi.nlm.nih.gov/28584041
Publikováno v:
Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. 108:196-202
Zusammenfassung Hintergrund Versicherte haben Anspruch auf regelmasige Untersuchungen zur Krankheitsfruherkennung (§25 SGB V). Individuelle Risiken werden im bestehenden Modell nicht systematisch berucksichtigt. Vor diesem Hintergrund wurde die Brem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30e9f9e02bfeec8911f5ad9c6e77b3c8
https://doi.org/10.1016/j.zefq.2013.12.002
https://doi.org/10.1016/j.zefq.2013.12.002
Autor:
Dominique Klauer, Goetz Schlotterbeck, Mathias Wind, Arnaud Serafyn, Helge Grunwald, Michael Schleimer, Patrick Hargreaves, Klaus Gebhardt, Anne Schmitt-Hoffmann
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 85:138-144
A systematic comparison between two labeling approaches for the investigation of the in vitro metabolic pattern of pharmaceutical drugs was performed by examining the use of (i) radiolabeled drugs analyzed with LC-MS-offline radiodetection and (ii) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded91f32d734efc12c90731b0aeb4a20
https://doi.org/10.1016/j.jpba.2013.07.004
https://doi.org/10.1016/j.jpba.2013.07.004
Autor:
Malcolm G. P. Page, Eric Desarbre, Beatrice Hofer, Klaus Gebhardt, Clothilde Dantier, Anne Schmitt-Hoffmann
Publikováno v:
Journal of Antimicrobial Chemotherapy. 68:1120-1129
Carbapenem resistance in Gram-negative bacteria, mediated by restricted net influx and carbapenem-hydrolysing β-lactamases, is a growing problem. The monosulfactam antibiotic BAL30072 is stable to most carbapenemases, suggesting that it could be com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6227d67be5ab50861d1370920e762ffe
https://doi.org/10.1093/jac/dks527
https://doi.org/10.1093/jac/dks527
Autor:
Klaus Gebhardt, Clothilde Dantier, Malcolm G. P. Page, Anne Schmitt-Hoffmann, Bérangère Gaucher, Eric Desarbre
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1510-1519
BAL30376 is a triple combination comprising a siderophore monobactam, BAL19764 ; a novel bridged monobactam, BAL29880 , which specifically inhibits class C β-lactamases; and clavulanic acid, which inhibits many class A and some class D β-lactamases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff91d00eebb1b8ebbd505f38d66de44b
https://doi.org/10.1128/aac.01370-10
https://doi.org/10.1128/aac.01370-10
Autor:
Gerhard Bringmann, Jochen Schinko, Klaus Gebhardt, Sven Meyer, Hans-Peter Fiedler, Axel Zeeck
Publikováno v:
The Journal of Antibiotics. 64:229-232
Four new terpenoglycoside antibiotics, phenalinolactones A-D were isolated from Streptomyces sp. Tü 6071. The structures were elucidated on the basis of detailed NMR and MS analyses. Phenalinolactones combine a diterpenoid tricycle, a 2,3,6-trideoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32f61e022f9f2227f07ea7dc2272a76
https://doi.org/10.1038/ja.2010.165
https://doi.org/10.1038/ja.2010.165
Autor:
Anne Schmitt-Hoffmann, Dominique Klauer, Mathias Wind, Patrick Roussel, Helge Grunwald, Michael Schleimer, Pascal Fullhardt, Jochen Spickermann, Klaus Illig, Claude Nuoffer, Klaus Gebhardt
Publikováno v:
Journal of Chromatography A. 1216:3946-3953
The in vitro metabolic profile of BAL30630, an antifungal piperazine propanol derivative, which inhibits the 1,3-beta- d -glucansynthase, was investigated by incubation with microsomes of several species and with rat hepatocytes. For the spotting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07571c51ae061a9fcc9ccee3c5a2170
https://doi.org/10.1016/j.chroma.2009.03.022
https://doi.org/10.1016/j.chroma.2009.03.022
Autor:
Jochen Spickermann, Klaus Gebhardt, Dominique Klauer, Massimiliano Donzelli, Mathias Wind, Anne Schmitt-Hoffmann, Rima Sturm-Haurany, Michael Schleimer, Pascal Fullhardt
Publikováno v:
Journal of Mass Spectrometry. 41:903-910
The metabolic profile of BAL4815, an antifungal azole drug, was determined using in vitro rat hepatocyte incubations and subsequent analysis by capillary LC-qTof-MS and MS/MS including accurate mass determination. For the detection of the metabolites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2228c68141ee88f75d74d9ae47756242
https://doi.org/10.1002/jms.1049
https://doi.org/10.1002/jms.1049
Publikováno v:
Rapid Communications in Mass Spectrometry. 19:2935-2942
Streptocidins, a family of tyrocidine-like cyclic decapeptides, are an ideal demonstration object for the detection and in situ structure analysis of natural compounds directly in microbial cells using whole cell matrix-assisted laser desorption/ioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23822c4369e9300f05833f60547b0530
https://doi.org/10.1002/rcm.2155
https://doi.org/10.1002/rcm.2155
Autor:
Günther Egidi, Klaus Gebhardt
Publikováno v:
Zeitschrift für Allgemeinmedizin. 79:181-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c5ae276cd8cc6350636637e64a085f
https://doi.org/10.1007/bf03653223
https://doi.org/10.1007/bf03653223