Výsledky vyhledávání - "Klaus Gaertner"

Elektronická kniha

Theory and Practice in the Interdisciplinary Production and Reproduction of Scientific Knowledge : ID in the XXI Century

Autor: Olga Pombo, Klaus Gärtner, Jorge Jesuíno

This book addresses the urgent need for a large and systematic analysis of current interdisciplinary (ID) research and practice. It demonstrates how ID is essentially a cognitive phenomenon, something different from the frivolous and inconsequential

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Elektronická kniha

The Mind-Technology Problem : Investigating Minds, Selves and 21st Century Artefacts

Autor: Robert W. Clowes, Klaus Gärtner, Inês Hipólito

This edited book deepens the engagement between 21st century philosophy of mind and the emerging technologies which are transforming our environment. Many new technologies appear to have important implications for the human mind, the nature of our c

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Strong and Selective Inhibitors of Hepatitis B Virus Replication among Novel N 4 -Hydroxy- and 5-Methyl-β- l -Deoxycytidine Analogues

Autor: Klaus Gaertner, E. Matthes, I. Krahn, Hüseyin Sirma, Hans Will, L. Lin, M. von Janta-Lipinski, Anneko Funk

Publikováno v: Antimicrobial Agents and Chemotherapy

Novel N 4 -hydroxy- and 5-methyl-modified β- l -deoxycytidine analogues were synthesized and evaluated as anti-hepatitis B virus (HBV) agents. Their in vitro efficiencies were investigated in HepG2.2.15 cells stably transfected with HBV. β- l -2′

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8479d3f57ddec1e423d5bb64b3657154
https://doi.org/10.1128/aac.00001-07

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Protein and RNA of Human Telomerase as Targets for Modified Oligonucleotides

Autor: Klaus Gaertner, E. Matthes, Jürgen Schildt, H. Scheer, M. von Janta-Lipinski, Christian Lehmann

Publikováno v: Nucleosides and Nucleotides. 18:1719-1720

Chimeric oligodeoxynucleotides containing phosphorothioate and N3′→P5′phosphoramidate linkages were synthesized. These oligomers show a high inhibitory activity against human telomerase.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b8f1fa1648e002f867d7b035b484e2
https://doi.org/10.1080/07328319908044832

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Synthesis and Anti-HIV Activity of Modified 2′,3′-Dideoxy-3′-Fluoro Pyrimidine Nucleosides

Autor: M. von Janta-Lipinski, Jürgen Schildt, Klaus Gaertner, D. Scholz, P. Langon, E. Matther

Publikováno v: Nucleosides and Nucleotides. 10:651-652

Among the 2′, 3′ -dideoxy-3′-fluoro pyrimidine nucleosidea modified at C-4 and C-5 several congeners have been identified which show a selective inhibition of HIV-1 replication in vitro.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9233a3fa7c644b4f9b39153bb6d3af78
https://doi.org/10.1080/07328319108046561

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