Výsledky vyhledávání - "Klaus G. Steube"

The necessity of identity assessment of animal intestinal cell lines: A case report

Autor: Anne-Leena Koelz, Cord C. Uphoff, Klaus G. Steube, Pablo Steinberg, Jeannette Kluess, Hans G. Drexler

Publikováno v: Cytotechnology. 64:373-378

Eight intestinal cell lines, established from different animal species were submitted to DSMZ (German Collection of Microorganisms and Cell Cultures) in order to analyze their species of origin and their microbial contamination. Species identity was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33870ea9d39e57ba9b0856e2be908426
https://doi.org/10.1007/s10616-011-9420-3

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New Communesin Derivatives from the Fungus Penicillium sp. Derived from the Mediterranean Sponge Axinella verrucosa

Autor: Albrecht Berg, Peter Proksch, Victor Wray, Klaus G. Steube, Ru Angelie Edrada, Karsten Schaumann, Raquel Jadulco, Rainer Ebel

Publikováno v: Journal of Natural Products. 67:78-81

The ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella verrucosa, yielded the known compound communesin B (1) and its new congeners communesins C (2) and D (3), as well as the known compounds griseofulvin, dechlo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b897a98260c8feb4425d8c25351d53db
https://doi.org/10.1021/np030271y

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Differential effects of staurosporine and its analogues on chemokine release by promyelocytic leukemia cell line NB-4

Autor: Peter Proksch, Corinna Meyer, Hans G. Drexler, Peter J. Schupp, Klaus G. Steube

Publikováno v: Leukemia Research. 27:957-963

The protein kinase inhibitor staurosporine elicits multiple responses in various systems. We evaluated nine naturally occurring staurosporine derivatives as modulators of chemokine production by monitoring the secretion of interleukin-8 (IL-8) and mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc9d0071ad43e00dcfc6a893b361a19
https://doi.org/10.1016/s0145-2126(03)00047-x

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Detection of pharmacologically active natural products using ecology. Selected examples from Indopacific marine invertebrates and sponge-derived fungi

Autor: Rainer Ebel, Wen H. Lin, Klaus G. Steube, RuAngelie Edrada, Peter J. Schupp, Peter Proksch, S. Sudarsono, Victor Wray

Publikováno v: Pure and Applied Chemistry. 75:343-352

This review article presents our group's recent research findings with regard to bioactive natural products from marine sponges and tunicates, as well as from sponge derived fungi. The organisms discussed originate in the Indopacific region, which ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::570201f08e4ccd885e3162cc82df9096
https://doi.org/10.1351/pac200375020343

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Melophlins C−O, Thirteen Novel Tetramic Acids from the Marine Sponge Melophlus sarassinorum

Autor: Sumali Wiryowidagdo, Klaus G. Steube, Victor Wray, Hua-Shi Guan, Bin-Gui Wang, Peter Proksch, Rob van Soest, Chang-Yun Wang, Rainer Ebel

Publikováno v: Journal of Natural Products. 66:51-56

Thirteen new metabolites, melophlins C-O (1-13), were identified from the marine sponge Melophlus sarassinorum. Compounds 1-13 represent tetramic acid derivatives that differ with regard to the nature of their alkyl side chains. The structures of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca84c0f98a9fd9d6e457c138a1ce14cc
https://doi.org/10.1021/np0202778

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Swinhoeiamide A, a New Highly Active Calyculin Derivative from the Marine Sponge Theonella swinhoei

Autor: Victor Wray, Rob van Soest, Rainer Ebel, Klaus G. Steube, RuAngelie Edrada-Ebel, Agus Supriyono, Peter Proksch, Peter J. Schupp

Publikováno v: Journal of natural products, 65(8), 1168-1172. American Chemical Society

Analysis of the Papua New Guinean sponge Theonella swinhoei afforded a new calyculinamide-related congener for which we propose the name swinhoeiamide A (1). The structure of the new compound was unambiguously established on the basis of NMR spectros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee53172ec3ec872cc5bcedea39f98d4
https://dare.uva.nl/personal/pure/en/publications/swinhoeiamide-a-a-new-highly-active-calyculin-derivative-from-the-marine-sponge-theonella-swinhoei(70e390d3-f40f-4479-9b54-b71a86c4f6ef).html

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Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm

Autor: Corinna Meyer, Klaus G. Steube, Peter J. Schupp, Peter Proksch

Publikováno v: Cancer Letters. 174:165-172

Nine indolocarbazole alkaloids of the staurosporine type, including three new derivatives, were evaluated for their potential as inhibitors of cell proliferation and macromolecule synthesis. Four derivatives were tested as inhibitors of cell prolifer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0852fdb4cb4ba78180660fbc5d3e0b
https://doi.org/10.1016/s0304-3835(01)00694-2

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MULTIPLE REGULATION OF CONSTITUTIVE AND INDUCED INTERLEUKIN 8 SECRETION IN HUMAN MYELOMONOCYTIC CELL LINES

Autor: Klaus G. Steube, Corinna Meyer, Hans G. Drexler

Publikováno v: Cytokine. 12:1236-1239

Secretion of interleukin 8 (IL-8) and its regulation was investigated in myelomonocytic leukaemia cell lines. Quantification by ELISA revealed a constitutive production in the cell lines HL-60, ML-2, MONO-MAC-6 and MUTZ-3 ranging between 1500 and ca.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be5cf6e241f4c7e71597aea604b4d1e
https://doi.org/10.1006/cyto.2000.0702

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Induction and Secretion of the Chemokines Interleukin-8 and Monocyte Chemotactic Protein-1 in Human Immature Leukemia Cell Lines

Autor: Hans G. Drexler, Klaus G. Steube, Corinna Meyer

Publikováno v: Molecular Cell Biology Research Communications. 3:60-65

We investigated expression and secretion of the chemokines interleukin-8 (IL-8) and monocyte chemotactic protein-1 (MCP-1) in human myeloid cell lines. Quantitative determination by ELISA revealed a significant constitutive production of both chemoki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec87468dd118d8efeaeb430f523eb136
https://doi.org/10.1006/mcbr.2000.0190

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