Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Klaus Fruh"'
Publikováno v:
J Infect Dis
Congenital cytomegalovirus (CMV) infection is the most common infectious cause of birth defects and neurological damage in newborns. Despite a well-established role for natural killer (NK) cells in control of CMV infection in older children and adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67217668939ede95ca3a0b17b3f1ed3c
https://doi.org/10.1093/infdis/jiac131
https://doi.org/10.1093/infdis/jiac131
Autor:
Daniel Malouli, Meenakshi Tiwary, Roxanne M. Gilbride, David W. Morrow, Colette M. Hughes, Andrea Selseth, Toni Penney, Priscila Castanha, Megan Wallace, Yulia Yeung, Morgan Midgett, Connor Williams, Jason Reed, Yun Yu, Lina Gao, Gabin Yun, Luke Treaster, Amanda Laughlin, Jeneveve Lundy, Jennifer Tisoncik-Go, Leanne S. Whitmore, Pyone P. Aye, Faith Schiro, Jason P. Dufour, Courtney R. Papen, Husam Taher, Louis J. Picker, Klaus Früh, Michael Gale, Nicholas J. Maness, Scott G. Hansen, Simon Barratt-Boyes, Douglas S. Reed, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract An influenza vaccine approach that overcomes the problem of viral sequence diversity and provides long-lived heterosubtypic protection is urgently needed to protect against pandemic influenza viruses. Here, to determine if lung-resident effe
Externí odkaz:
https://doaj.org/article/30aee6ee13914e60b17c02c57c123179
Autor:
Claire E Otero, Cody S Nelson, Elizabeth Scheef, Lesli Sprehe, Matilda Mostrom, Daniel Malouli, Klaus Fruh, Cliburn Chan, Amitinder Kaur, Sallie R Permar
Publikováno v:
The Journal of Immunology. 208:126.36-126.36
Congenital cytomegalovirus (cCMV) is the most common in utero infection and causes major neurodevelopmental deficits, but there remains no licensed vaccine to prevent cCMV. Little is known about maternal immune responses that can prevent placental CM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34be57d877f50d9fd6e292a9d7261d9e
https://doi.org/10.4049/jimmunol.208.supp.126.36
https://doi.org/10.4049/jimmunol.208.supp.126.36
Autor:
L. Ravi F Iyer, Marieke C Verweij, Sujit Nair, David Morrow, Mandana Mansouri, Teresa Beechwood, Christine Meyer, Dimple Chakravarty, Luke Uebelhoer, Abigail Ventura, Elvin J Lauron, Andrea Selseth, Michael Axthelm, Evan F Lind, Jennifer Saultz, Janet Douglas, Alan Korman, Nina Bhardwaj, Ashutosh K Tewari, Scott G. Hansen, Daniel Malouli, Louis J Picker, Klaus Fruh
Publikováno v:
The Journal of Immunology. 208:66.15-66.15
Pre-clinical models in non-human primates demonstrate that cytomegalovirus (CMV)-vectored vaccines are unique in their ability to elicit and indefinitely maintain high frequencies of polyfunctional effector memory T cells to heterologous pathogen ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddc431beb311d5be4d4e40010cc5210c
https://doi.org/10.4049/jimmunol.208.supp.66.15
https://doi.org/10.4049/jimmunol.208.supp.66.15
Autor:
Meaghan Hancock, Scott Hansen, Daniel Malouli, Emily Marshall, Collette Hughes, Kurt T. Randall, David Morrow, Julia Ford, Roxanne Gilbride, Andrea Selseth, Renee Espinosa Trethewy, Lindsey Bishop, Kelli Oswald, Rebecca Shoemaker, Brian Berkemeier, William Bosche, Michael Hull, Michael Nekorchuk, Kathleen Busman-Sahay, Jacob Estes, Michael Axthelm, Jeremy Smedley, Danica Shao, Paul Edlefsen, Jeffrey Lifson, Klaus Fruh, Jay Nelson, Louis J Picker
Publikováno v:
The Journal of Immunology. 208:64.18-64.18
Strain 68-1 rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens demonstrate a vaccine efficacy where 50–60% of vaccinated rhesus macaques are protected from SIV challenge. Intriguingly, RhCMV/SIV vectors e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f56a0f78ae622525c415693f8e16e94
https://doi.org/10.4049/jimmunol.208.supp.64.18
https://doi.org/10.4049/jimmunol.208.supp.64.18
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E (HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability to bind alleles of the major histocompatibility complex E (MHC-E) protein
Externí odkaz:
https://doaj.org/article/fdfd46d1a98a4b46a94c1f7c13ac7742
Autor:
Claire E Otero, Richard Barfield, Elizabeth Scheef, Cody S Nelson, Nicole Rodgers, Hsuan-Yuan Wang, Matilda J Moström, Tabitha D Manuel, Julian Sass, Kimberli Schmidt, Husam Taher, Courtney Papen, Lesli Sprehe, Savannah Kendall, Angel Davalos, Peter A Barry, Klaus Früh, Justin Pollara, Daniel Malouli, Cliburn Chan, Amitinder Kaur, Sallie R Permar
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011378 (2023)
Cytomegalovirus (CMV) is the most common congenital infection and cause of birth defects worldwide. Primary CMV infection during pregnancy leads to a higher frequency of congenital CMV (cCMV) than maternal re-infection, suggesting that maternal immun
Externí odkaz:
https://doaj.org/article/c5d4db2c414e4452a4d70b4bd935fc85
Autor:
Matilda J Moström, Shan Yu, Dollnovan Tran, Frances M Saccoccio, Cyril J Versoza, Daniel Malouli, Anne Mirza, Sarah Valencia, Margaret Gilbert, Robert V Blair, Scott Hansen, Peter Barry, Klaus Früh, Jeffrey D Jensen, Susanne P Pfeifer, Timothy F Kowalik, Sallie R Permar, Amitinder Kaur
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011646 (2023)
Congenital cytomegalovirus (cCMV) is the leading infectious cause of neurologic defects in newborns with particularly severe sequelae in the setting of primary CMV infection in the first trimester of pregnancy. The majority of cCMV cases worldwide oc
Externí odkaz:
https://doaj.org/article/1f4052f269cf4439b401b378a9c37424
Autor:
Sanjay Vashee, Timothy B. Stockwell, Nina Alperovich, Evgeniya A. Denisova, Daniel G. Gibson, Kyle C. Cady, Kristofer Miller, Krishna Kannan, Daniel Malouli, Lindsey B. Crawford, Alexander A. Voorhies, Eric Bruening, Patrizia Caposio, Klaus Fruh, Michael J. Imperiale, Eain Murphy, Richard Stanton
Publikováno v:
mSphere
mSphere, Vol 2, Iss 5 (2017)
mSphere, Vol 2, Iss 5, p e00331-17 (2017)
mSphere, Vol 2, Iss 5 (2017)
mSphere, Vol 2, Iss 5, p e00331-17 (2017)
The genomes of large DNA viruses, such as human cytomegalovirus (HCMV), are difficult to manipulate using current genetic tools, and at this time, it is not possible to obtain, molecular clones of CMV without extensive tissue culture. To overcome the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d08898b45afbfab0295ea6414a29dc9
http://europepmc.org/articles/PMC5628293
http://europepmc.org/articles/PMC5628293
Autor:
Jake C. Harbour, Mahmoud Abdelbary, John B. Schell, Samantha P. Fancher, Jack J. McLean, Taylen J. Nappi, Susan Liu, Timothy J. Nice, Zheng Xia, Klaus Früh, Jeffrey C. Nolz
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112407- (2023)
Summary: Poxvirus infections of the skin are a recent emerging public health concern, yet the mechanisms that mediate protective immunity against these viral infections remain largely unknown. Here, we show that T helper 1 (Th1) memory CD4+ T cells a
Externí odkaz:
https://doaj.org/article/6e4c0481da4d4781a64b5fe1b2ada48a