Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Klaus Flechsenhar"'
Autor:
Jeffrey B. Driban, Lori Lyn Price, Bing Lu, Klaus Flechsenhar, Grace H. Lo, Timothy E. McAlindon
Publikováno v:
Seminars in Arthritis and Rheumatism. 58:152148
We aimed to describe the natural history leading to end-stage knee osteoarthritis (esKOA), focusing on knee symptoms, radiographic severity, and the presence of limited mobility or instability.We performed knee-based analyses of Osteoarthritis Initia
Publikováno v:
Seminars in Arthritis and Rheumatism. 49:3-8
Objective We previously published data representing calculations for sample sizes assuming that the reduction of the incidence of knee joint replacement (KJR) would be an endpoint to prove efficacy of a disease-modifying drug in osteoarthritis (DMOAD
Autor:
Paul J. Bryce, Danping Ding-Pfennigdorff, Matthias Herrmann, Klaus Flechsenhar, Frank O. Nestle, Peter Florian, Eckart Bartnik
Publikováno v:
Experimental Dermatology. 29:4-14
Due to the clinical development of drugs such as secukinumab, ustekinumab and dupilumab, major changes have been achieved in the treatment of patients diagnosed with psoriasis and atopic dermatitis. In academia and the pharmaceutical industry, resear
Autor:
Daniel Crowther, Axel Dietrich, Janina S. Ried, Klaus Flechsenhar, Felix Eckstein, Eckart Bartnik
Publikováno v:
Arthritis & Rheumatology. 67:3174-3183
Objective To evaluate the extent to which the current designs of clinical trials in knee osteoarthritis (OA) permit detection of a therapeutic effect of disease-modifying OA drugs (DMOADs) on the incidence of knee replacement, and to provide estimate
Publikováno v:
Journal of Arthritis. 5
Autor:
David Burstein, John L. Griffith, Lori L. Price, M. Nuite, Klaus Flechsenhar, Nitya Krishnan, Timothy E. McAlindon, Robin Ruthazer
Publikováno v:
Osteoarthritis and Cartilage. 19(4):399-405
summary Objective: To determine whether either of two magnetic resonance imaging approaches e delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC), or T2 mapping e can detect short-term changes in knee hyaline cartilage among
Autor:
Steffen Dr. Oesser, Klaus Flechsenhar, Burkhard Schlosshauer, M. Suckfuell, Michael Ahlers, Reiner Hajosch
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :372-379
To more effectively manage the substantial bleeding encountered during surgical procedures in oto-rhino-laryngology, we developed a novel hemostatic sponge made of pharmaceutical grade, chemically cross-linked gelatin. The sponge is characterized by
Autor:
Janina S, Ried, Klaus, Flechsenhar, Eckart, Bartnik, Daniel, Crowther, Axel, Dietrich, Felix, Eckstein
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 67(12)
To evaluate the extent to which the current designs of clinical trials in knee osteoarthritis (OA) permit detection of a therapeutic effect of disease-modifying OA drugs (DMOADs) on the incidence of knee replacement, and to provide estimates of the r
Autor:
Eckart Bartnik, Lenore Teichert, Janina S. Ried, Timothy E. McAlindon, Matthias Herrmann, Klaus Flechsenhar
Publikováno v:
Journal of Biomedical Research
To evaluate in an interventional trial on knee osteoarthritis (OA) the level and change of two serum biomarkers and their correlation with imaging parameters. The previously reported interventional OA study (ClinicalTrials.gov: NCT00536302) identifie
Publikováno v:
World Journal of Surgery. 25:1367-1372
The primitive neuroectodermal tumor (PNET) is an extremely aggressive soft tissue neoplasm that occurs in children and adolescents. We retrospectively reviewed our therapeutic experience with a multidisciplinary approach, combining surgery, chemother