Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Klaus Eckert"'
Autor:
Jane D. Holland, Balázs Györffy, Regina Vogel, Klaus Eckert, Giovanni Valenti, Liang Fang, Philipp Lohneis, Sefer Elezkurtaj, Ulrike Ziebold, Walter Birchmeier
Publikováno v:
Cell Reports, Vol 5, Iss 5, Pp 1214-1227 (2013)
Prognosis for patients with estrogen-receptor (ER)-negative basal breast cancer is poor, and chemotherapy is currently the best therapeutic option. We have generated a compound-mutant mouse model combining the activation of β-catenin and HGF (Wnt-Me
Externí odkaz:
https://doaj.org/article/138326b544464410abf510578ab14508
Autor:
Silvia Heringer-Walther, Klaus Eckert, Sarah-Mai Schumacher, Lutz Uharek, Annika Wulf-Goldenberg, Florian Gembardt, Iduna Fichtner, Heinz-Peter Schultheiss, Kathy Rodgers, Thomas Walther
Publikováno v:
Haematologica, Vol 94, Iss 6 (2009)
Effects of angiotensin (Ang)-(1–7), an AngII metabolite, on bone marrow-derived hematopoietic cells were studied. We identified Ang-(1–7) to stimulate proliferation of human CD34+ and mononuclear cells in vitro. Under in vivo conditions, we monit
Externí odkaz:
https://doaj.org/article/0feff2195f8e425783de9c60b7c18383
Autor:
Özlem Akilli Öztürk, Walter Birchmeier, Daniel Besser, Johannes Fritzmann, Jane D. Holland, Yong Yu, Jingjing Qi, Klaus Eckert, Annika Wulf-Goldenberg, Iduna Fichtner
Publikováno v:
Gut. 65:1690-1701
Objectives We have previously identified a 115-gene signature that characterises the metastatic potential of human primary colon cancers. The signature included the canonical Wnt target gene BAMBI , which promoted experimental metastasis in mice. Her
Autor:
Maria Stecklum, Annika Wulf-Goldenberg, Klaus Eckert, Iduna Fichtner, Bettina Purfürst, Marlen Keil, Antje Siegert
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 51:183-191
In the present study, purified human cord blood stem cells were co-cultivated with murine hepatic alpha mouse liver 12 (AML12) cells to compare the effect on endodermal stem cell differentiation by either direct cell-cell interaction or by soluble fa
Publikováno v:
Tissue and Cell. 44:80-86
In vivo studies concerning the function of human hematopoietic stem cells (HSC) are limited by relatively low levels of engraftment and the failure of the engrafted HSC preparations to differentiate into functional immune cells after systemic applica
Autor:
Alessandro Prigione, M. Rivero, Justyna Jozefczuk, Harald Stachelscheid, Petter Björquist, Annika Wulf-Goldenberg, Katrin Zeilinger, R. Strehl, Thomas Urbaniak, J. C. Gerlach, Klaus Eckert, James Adjaye, P. Bussmann, Josefina Edsbagge, Janne Jensen
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 7:729-741
Teratoma formation in mice is today the most stringent test for pluripotency that is available for human pluripotent cells, as chimera formation and tetraploid complementation cannot be performed with human cells. The teratoma assay could also be app
Publikováno v:
Cytotherapy. 13:108-113
Humanized mice were generated in order to investigate the anti-tumor efficacy of bispecific antibodies. The engraftment, distribution and differentiation of mononuclear cells (MNC) from cord blood transplanted into the liver of newborn non-obese diab
Autor:
Reinhard Henschler, Brigitte Rüster, Erhard Seifried, Lisa Keller, Klaus Eckert, Erika Deak, Iduna Fichtner
Publikováno v:
Cytotherapy. 12:260-264
Intravenous (i.v.) transplantation and subsequent homing of Mesenchymal Stromal Cells (MSC) may be adversely influenced by their relatively high adhesion capacity and their tendency to aggregate, leading to clogging of capillaries especially in the l
Publikováno v:
International Immunopharmacology. 9:1298-1303
beta-glucans are biological response modifiers with activatory effects on macrophages, dendritic cells (DC), granulocytes and NK cells. In this study, we investigated the effect of a soluble yeast-derived beta-(1-3), (1-6)-D-glucan on prophylactic pe
Autor:
Heinz-Peter Schultheiss, Silvia Heringer-Walther, Kathy Rodgers, Sarah-Mai Schumacher, Florian Gembardt, Iduna Fichtner, Annika Wulf-Goldenberg, Lutz Uharek, Thomas Walther, Klaus Eckert
Publikováno v:
Haematologica. 94:857-860
Effects of angiotensin (Ang)-(1–7), an AngII metabolite, on bone marrow-derived hematopoietic cells were studied. We identified Ang-(1–7) to stimulate proliferation of human CD34+ and mononuclear cells in vitro. Under in vivo conditions, we monit