Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Klaus E. Kuettner"'
Autor:
Eugene J.-M. A. Thonar, James M. Williams, Brian A. Maldonado, Mary Ellen Lenz, Thomas J. Schnitzer, Giles V. Campion, Klaus E. Kuettner, M. Barry, E. Sweet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::772213f15b826817be9443f581ce6c97
https://doi.org/10.1201/9781003066255-18
https://doi.org/10.1201/9781003066255-18
Autor:
Matthias Aurich, Bernd Rolauffs, Wilhelm K. Aicher, Kuno Weise, Christian Bahrs, Alan J. Grodzinsky, Miriam Rothdiener, Klaus E. Kuettner, Andreas Badke, Bodo Kurz
Publikováno v:
Arthritis & Rheumatism. 63:1637-1647
Objective Superficial articular chondrocytes display distinct spatial remodeling processes in response to the onset of distant osteoarthritis (OA). Such processes may be used to diagnose early events before manifest OA results in tissue destruction a
Autor:
Michael W. Lark, Jorge O. Galante, Joshua J. Jacobs, Lori A. Hoerrner, Katalin Mikecz, Jianling Yao, Tibor T. Glant, Klaus E. Kuettner, Nancy I. Hutchinson
Publikováno v:
Journal of Bone and Mineral Research. 10:1417-1427
Periprosthetic osteolysis with or without aseptic loosening is a major clinical problem in total hip arthroplasty. While the macrophage response to prosthetic wear debris and its role in periprosthetic osteolysis has been extensively studied, informa
Publikováno v:
Journal of Structural Biology. 162:335-344
A better understanding of the unique cellular and functional properties of the superficial zone of articular cartilage may aid current strategies in tissue engineering which attempts a layered design for the repair of cartilage lesions to avert or po
Autor:
Ada A. Cole, Klaus E. Kuettner
Publikováno v:
Osteoarthritis and Cartilage. 13(2):93-103
SummaryVariations among joints in the initiation and progression of degeneration may be explained, in part, by metabolic, biochemical and biomechanical differences. Compared to the cartilage in the knee joint, ankle cartilage has a higher content of
Autor:
Thomas Aigner, Stephan Söder, David C. Rueger, Klaus E. Kuettner, Susan Chubinskaya, Arnavaz A. Hakimiyan
Publikováno v:
Arthritis & Rheumatism. 52:468-478
Objective To delineate the role of endogenous osteogenic protein 1 (OP-1) in human articular cartilage homeostasis via the inhibition of OP-1 gene expression by antisense oligonucleotides. Methods Human adult normal articular cartilage was obtained f
Autor:
Klaus E. Kuettner, A. Reiner, Jens O. Anders, Matthias Aurich, Juergen Mollenhauer, Ada A. Cole, A. Robin Poole, Renée A. Fuhrmann, Fackson Mwale
Publikováno v:
Arthritis & Rheumatism. 54:244-252
Objective Although cartilage lesions occur in the ankles, osteoarthritis rarely develops in the ankles, suggesting that ankle cartilage can up-regulate mechanisms to repair the damaged matrix. To define these processes, we compared cartilage samples
Autor:
Fulvia Arfelli, Juergen Mollenhauer, Andreas Wagner, Klaus E. Kuettner, Joachim Metge, Carol Muehleman, Ralf Hendrik Menk, Sharmila Majumdar, Gabriele Heitner, Luigi Rigon, Bernd Reime, Ahi Sema Issever
Publikováno v:
Osteoarthritis and Cartilage. 12(2):97-105
Objective: To determine the feasibility of detecting the structural orientation in cartilage with Diffraction Enhanced X-Ray Imaging. Design: Human tali and femoral head specimens were Diffraction Enhanced X-Ray Imaged (DEI) at the SYRMEP beamline at
Autor:
Klaus E. Kuettner, Susan Chubinskaya
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 35:1323-1340
The purpose of this review is to summarize the current scientific knowledge of bone morphogenetic proteins (BMPs) in adult articular cartilage. We specifically focus on adult cartilage, since one of the major potential applications of the members of
Autor:
Klaus E. Kuettner, Charis Merrihew, David C. Rueger, Bhavna Kumar, Katherine Heretis, Susan Chubinskaya
Publikováno v:
Journal of Orthopaedic Research. 21:899-907
A synchronized balance between synthesis and breakdown of extracellular matrix (ECM) molecules in normal articular cartilage is disturbed in osteoarthritis (OA). The focus of our study is the anabolic factor, osteogenic protein-1 (OP-1) that is expre