Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Klaus D Molle"'
Autor:
Kathrin Thedieck, Pazit Polak, Man Lyang Kim, Klaus D Molle, Adiel Cohen, Paul Jenö, Cécile Arrieumerlou, Michael N Hall
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1217 (2007)
TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two functionally and structurally distinct multiprotein complexes termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). In the p
Externí odkaz:
https://doaj.org/article/5d10bffc3d004f12b52f9f7f7214d0df
Autor:
Daniela Brodbeck, Lorenza Wyder Peters, Marie Goxe, Klaus D. Molle, Urs Regenass, Philippe Guerry, Michael N. Hall, Christoph Moroni, Marco Colombi, Agnes Knopf, Anke Thiemeyer
Publikováno v:
SLAS Discovery. 19:131-144
The mTOR pathway is a critical integrator of nutrient and growth factor signaling. Once activated, mTOR promotes cell growth and proliferation. Several components of the mTOR pathway are frequently deregulated in tumors, leading to constitutive activ
Autor:
Michael N. Hall, Marco Colombi, Christoph Moroni, Klaus D. Molle, Charles Betz, Urs Regenass, A Thiemeyer, C Schaefer, K Rattenbacher-Kiser, Don Benjamin
Publikováno v:
Oncogene
Release from growth factor dependence and acquisition of signalling pathway addiction are critical steps in oncogenesis. To identify genes required on mammalian target of rapamycin (mTOR) addiction, we performed a genome-wide short hairpin RNA screen
Publikováno v:
Circulation Research. 100:79-87
A central regulator of cell growth that has been implicated in responses to stress such as hypoxia is mTOR ( m ammalian T arget O f R apamycin). We have shown previously that mTOR is required for angiogenesis in vitro and endothelial cell proliferati
Autor:
Andreas L. Serra, Klaus D. Molle, Michael N. Hall, Patricia R. Wahl, Michel Le Hir, Rudolf P. Wüthrich
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by dysregulated tubular epithelial cell growth, resulting in the formation of multiple renal cysts and progressive renal failure. To date, there is no effective treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abba286d89f826d7d53f1f18b3a6dec9
Publikováno v:
Mech. Dev.
Mech. Dev., 2004, 121, pp.143-156. ⟨10.1016/j.mod.2003.12.005⟩
Mech. Dev., 2004, 121, pp.143-156. ⟨10.1016/j.mod.2003.12.005⟩
During development of the chick central nervous system, the trajectories of the descending medial and lateral longitudinal fascicles (MLF and LLF) are pioneered by axons originating from the interstitial nucleus of Cajal (INC) and the mesencephalic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6c95195c0c8137f643c721ed653160
https://hal.archives-ouvertes.fr/hal-00077678
https://hal.archives-ouvertes.fr/hal-00077678
Autor:
Michael N. Hall, Pazit Polak, Cécile Arrieumerlou, Paul Jenö, Klaus D. Molle, Man Lyang Kim, Kathrin Thedieck, Adiel Cohen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 11, p e1217 (2007)
PLoS ONE, 2(11):1217. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 2, Iss 11, p e1217 (2007)
PLoS ONE, 2(11):1217. PUBLIC LIBRARY SCIENCE
TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two functionally and structurally distinct multiprotein complexes termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). In the p
Autor:
Patricia R. Wahl, Andreas L. Serra, Michel Le Hir, Klaus D. Molle, Michael N. Hall, Rudolf P. Wüthrich
Publikováno v:
Nephrology Dialysis Transplantation; Mar2006, Vol. 21 Issue 3, p598-604, 7p