Data from Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

Autor: Katrin Lamszus, Eva Tolosa, Mascha Binder, Manfred Westphal, Sven Peine, Nils O. Schmidt, Tobias Martens, Miriam Schaper, Mareike Holz, Svenja Zapf, Nuray Akyüz, Christina Gehbauer, Jakob Matschke, Klaus C. Mende, Laura Glau, Alessandra Rünger, Cecile L. Maire, Simon Schliffke, Malte Mohme

Purpose: Immunotherapeutic treatment strategies for glioblastoma (GBM) are under investigation in clinical trials. However, our understanding of the immune phenotype of GBM-infiltrating T cells (tumor-infiltrating lymphocytes; TILs) and changes durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd05f4683adce883231213c3f207698
https://doi.org/10.1158/1078-0432.c.6526032.v1

Suppl. Fig. 4 from Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

Autor: Katrin Lamszus, Eva Tolosa, Mascha Binder, Manfred Westphal, Sven Peine, Nils O. Schmidt, Tobias Martens, Miriam Schaper, Mareike Holz, Svenja Zapf, Nuray Akyüz, Christina Gehbauer, Jakob Matschke, Klaus C. Mende, Laura Glau, Alessandra Rünger, Cecile L. Maire, Simon Schliffke, Malte Mohme

Supplemental data of next-generation T-cell receptor sequencing.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f65c6125787b2579ac838f3078152b
https://doi.org/10.1158/1078-0432.22465473.v1

Suppl. Fig. 3 from Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

Autor: Katrin Lamszus, Eva Tolosa, Mascha Binder, Manfred Westphal, Sven Peine, Nils O. Schmidt, Tobias Martens, Miriam Schaper, Mareike Holz, Svenja Zapf, Nuray Akyüz, Christina Gehbauer, Jakob Matschke, Klaus C. Mende, Laura Glau, Alessandra Rünger, Cecile L. Maire, Simon Schliffke, Malte Mohme

Additional cytokines determined by multiplex flow-cytometry after PHA stimulation of PBL.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7147cddac3293b241333686147d66e9a
https://doi.org/10.1158/1078-0432.22465476.v1

Suppl. Fig. 1 from Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

Autor: Katrin Lamszus, Eva Tolosa, Mascha Binder, Manfred Westphal, Sven Peine, Nils O. Schmidt, Tobias Martens, Miriam Schaper, Mareike Holz, Svenja Zapf, Nuray Akyüz, Christina Gehbauer, Jakob Matschke, Klaus C. Mende, Laura Glau, Alessandra Rünger, Cecile L. Maire, Simon Schliffke, Malte Mohme

Flow-cytometry gating strategy for T-cell differentiation and exhaustion markers.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f34c8412ceef4fb85e8bf4ef20d128
https://doi.org/10.1158/1078-0432.22465482

Contributors

Autor: Adriana Albani, Luigi Albano, Thiago Albonette-Felicio, Krystallenia I. Alexandraki, Ali Alomari, Natasha M. Appelman-Dijkstra, John R. Apps, Anna Aulinas, Garni Barkhoudarian, Lina Raffaella Barzaghi, Waiel Bashari, Benjamin Bender, Martin Bidlingmaier, Nienke R. Biermasz, Marcello D. Bronstein, Michael Buchfelder, Rolf Buslei, Ricardo L. Carrau, Philippe Chanson, Mirjam Christ-Crain, Kim M.J.A. Claessen, Aaron A. Cohen-Gadol, Jens Conrad, Alex Corlin, Sherwin Criseno, Olaf M. Dekkers, Donald K. Detchou, Timo Deutschbein, Christina Dimopoulou, Vincent Dodson, Michal Ehrenwald, Ulf Elbelt, Jean Anderson Eloy, Daniela Esposito, Melissa Fischer, Maria Fleseriu, Jörg Flitsch, Athanasios Fountas, Merav Fraenkel, Stefano Frara, Rüdiger Gerlach, Sabrina Giese, Daniel Gillett, Andrea Giustina, Andrea Glezer, Yona Greenman, Ashley Grossman, Rachel Grossman, Anca-Ligia Grosu, Agnieszka Grzywotz, Mark Gurnell, Angelika Gutenberg, Ross Hamblin, Christina Hayes, Anthony P. Heaney, Benjamin K. Hendricks, José Miguel Hinojosa-Amaya, Bernhard Hirt, Jürgen Honegger, Mirela Diana Ilie, Raquel S. Jallad, Gudmundur Johannsson, Emmanuel Jouanneau, Caroline Jung-Sievers, Niki Karavitaki, Daniel F. Kelly, Alan Kelsall, Ulrich J. Knappe, Arend Koch, Ilonka Kreitschmann-Andermahr, Sebastian Küchlin, Sarah Kullman, Wolf Alexander Lagrèze, Chloe Y. Li, Dror Limon, Michael Linetsky, Kirstie Lithgow, James K. Liu, Sofia Llahana, Marco Losa, Anton Luger, James MacFarlane, Marcio C. Machado, Luigi Maione, Juan Pedro Martinez-Barbera, Ma Antonia Martínez-Momblán, Rafael Martinez-Perez, Shirley McCartney, Klaus C. Mende, Pietro Mortini, Hermann L. Müller, Isabella Nasi-Kordhishti, John Newell-Price, Nils Henrik Nicolay, Tobias Pantel, Alberto M. Pereira, Stephan Petersenn, Daniel M. Prevedello, Oskar Ragnarsson, Redi Rahmani, Gérald Raverot, Michal Raz, Eugenia Resmini, Wolfgang Saeger, Alicia Santos, Marie Helene Schernthaner-Reiter, Katharina Schilbach, Sven-Martin Schlaffer, Jochen Schopohl, Henry W.S. Schroeder, Russell Senanayake, Ilan Shimon, Giuliano Silveira-Bertazzo, Ariadni Spyroglou, Sylvère Störmann, Jai Deep Thakur, Marily Theodoropoulou, Samuel B. Tomlinson, Elena Valassi, Elena V. Varlamov, G. Edward Vates, Greisa Vila, Susan M. Webb, Helmut Wilhelm, Peter Wolf, Yingying Yang, Yining Zhao

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33ea12c30bbc018d9dd1b4fd79233a71
https://doi.org/10.1016/b978-0-12-819949-7.09993-5