Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Klaus A. Hamacher"'
Autor:
Charles W. Stearns, John L. Humm, Luc Bidaut, Howard Amols, Assen S. Kirov, A. Ganin, Sadek Nehmeh, Yusuf E. Erdi, David Leo McDaniel, Klaus A. Hamacher, C. Ross Schmidtlein
Publikováno v:
Medical Physics. 33:198-208
The recently developed GATE (GEANT4 application for tomographic emission) Monte Carlo package, designed to simulate positron emission tomography (PET) and single photon emission computed tomography (SPECT) scanners, provides the ability to model and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac103c7f9d0595907ab5bd8acfc192b
https://doi.org/10.1118/1.2089447
https://doi.org/10.1118/1.2089447
Autor:
Shankar Vallabhajosula, Shota Konishi, Paresh J. Kothari, Stanley J. Goldsmith, Neil H. Bander, Diago Bastidas, Klaus A. Hamacher
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 19:706-715
Determination of the immunoreactive fraction (IF) of radiolabeled monoclonal antibodies (MAb) is essential to the understanding of the effects of radiolabeling and subsequent target-specific tumor localization. There has been generally no accepted me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcb2d98b2725741e694493c5ee49f1d
https://doi.org/10.1089/cbr.2004.19.706
https://doi.org/10.1089/cbr.2004.19.706
Autor:
Åse Ballangrud, Michael R. McDevitt, George Sgouros, Klaus A. Hamacher, Ronald D. Finn, Dangshe Ma, Joseph G. Jurcic, David A. Scheinberg, Roger Molinet, Steven M. Larson, John Humm, Chaitanya R. Divgi, Martin W. Brechbiel
Publikováno v:
Blood. 100:1233-1239
Unlike β particle–emitting isotopes, α emitters can selectively kill individual cancer cells with a single atomic decay. HuM195, a humanized anti-CD33 monoclonal antibody, specifically targets myeloid leukemia cells and has activity against minim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b94f6b8fda2f07637b226a5981b6224
https://doi.org/10.1182/blood.v100.4.1233.h81602001233_1233_1239
https://doi.org/10.1182/blood.v100.4.1233.h81602001233_1233_1239
Autor:
Klaus A. Hamacher, George Sgouros
Publikováno v:
Medical Physics. 28:1857-1874
The toxicity and clinical utility of long-lived alpha emitters such as Ac-225 and Ra-223 will depend upon the fate of alpha-particle emitting unstable intermediates generated after decay of the conjugated parent. For example, decay of Ac-225 to a sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5734a08c9f6e6ac5cc6a6530ae8a2ed9
https://doi.org/10.1118/1.1395026
https://doi.org/10.1118/1.1395026
Autor:
George Sgouros, Klaus A. Hamacher
Publikováno v:
Medical Physics. 26:2526-2528
The dosimetry of alpha particle emitters requires that all decays, including those of unstable intermediates be included in the calculation. Such calculations are complicated by the potential differential biologic distribution of each of the intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a85da9d9aa4a1cf5075d327f936641c
https://doi.org/10.1118/1.598788
https://doi.org/10.1118/1.598788
Autor:
Joseph T. Giacino, Nicholas D. Schiff, Douglas Ballon, Bradley J. Beattie, Richard Watts, Erik J. Kobylarz, Aziz M. Uluç, Henning U. Voss, Linda Heier, Klaus A. Hamacher, Bruce D. McCandliss, Stanley J. Goldsmith, Shankar Vallabhajosula, Jonathan P. Dyke
We used diffusion tensor imaging (DTI) to study 2 patients with traumatic brain injury. The first patient recovered reliable expressive language after 19 years in a minimally conscious state (MCS); the second had remained in MCS for 6 years. Comparis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d28e25096bba9e25bd2597a2bfc226
https://europepmc.org/articles/PMC1483160/
https://europepmc.org/articles/PMC1483160/
Autor:
Shankar, Vallabhajosula, Stanley J, Goldsmith, Klaus A, Hamacher, Lale, Kostakoglu, Shota, Konishi, Mathew I, Milowski, David M, Nanus, Neil H, Bander
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 46(5)
In radioimmunotherapy, myelotoxicity due to bone marrow radiation-absorbed dose is the predominant factor and frequently is the dose-limiting factor that determines the maximum tolerated dose (MTD). With (90)Y- and (131)I-labeled monoclonal antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4912c95ce32cda15ba035cf9715cc57
https://pubmed.ncbi.nlm.nih.gov/15872360
https://pubmed.ncbi.nlm.nih.gov/15872360
Autor:
Shankar, Vallabhajosula, Ichei, Kuji, Klaus A, Hamacher, Shota, Konishi, Lale, Kostakoglu, Paresh A, Kothari, Mathew I, Milowski, David M, Nanus, Neil H, Bander, Stanley J, Goldsmith
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 46(4)
111In-Labeled antibodies and peptides have been routinely used as chemical and biologic surrogates for 90Y-labeled therapeutic agents. However, recent studies have shown that there are significant differences in biodistribution between 111In- and 90Y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6d6ae05b7c4fa889f64dcb426143dbe
https://pubmed.ncbi.nlm.nih.gov/15809486
https://pubmed.ncbi.nlm.nih.gov/15809486
Autor:
Joseph G, Jurcic, Steven M, Larson, George, Sgouros, Michael R, McDevitt, Ronald D, Finn, Chaitanya R, Divgi, Ase M, Ballangrud, Klaus A, Hamacher, Dangshe, Ma, John L, Humm, Martin W, Brechbiel, Roger, Molinet, David A, Scheinberg
Publikováno v:
Blood. 100(4)
Unlike beta particle-emitting isotopes, alpha emitters can selectively kill individual cancer cells with a single atomic decay. HuM195, a humanized anti-CD33 monoclonal antibody, specifically targets myeloid leukemia cells and has activity against mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c82ecc4457035f04ffeec9c6c75c55a
https://pubmed.ncbi.nlm.nih.gov/12149203
https://pubmed.ncbi.nlm.nih.gov/12149203
Autor:
Howard Amols, Klaus A. Hamacher, Yusuf E. Erdi, Assen S. Kirov, Luc Bidaut, John L. Humm, Charles Schmidtlein, Sadek Nehmeh
Publikováno v:
Medical Physics. 32:1900-1901
Purpose: The needs of radiation therapytreatment planning impose higher demands on PET/CT imaging accuracy. The recently developed GATE (Geant4 Application for Tomographic Emission) Monte Carlo package, provides the possibility to model accurately th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4e93a8e8fe093d24de771aff96b3759
https://doi.org/10.1118/1.1997467
https://doi.org/10.1118/1.1997467