Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Klaus, Steger"'
Autor:
Ondrej Sanovec, Michaela Frolikova, Veronika Kraus, Jana Vondrakova, Maryam Qasemi, Daniela Spevakova, Ondrej Simonik, Lindsay Moritz, Drew Lewis Caswell, Frantisek Liska, Lukas Ded, Jiri Cerny, Tomer Avidor-Reiss, Saher Sue Hammoud, Hubert Schorle, Pavla Postlerova, Klaus Steger, Katerina Komrskova
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
There is a well-established link between abnormal sperm chromatin states and poor motility, however, how these two processes are interdependent is unknown. Here, we identified a possible mechanistic insight by showing that Protamine 2, a nuclear DNA
Externí odkaz:
https://doaj.org/article/01217af291054fa2bce783d7e7012b4f
Publikováno v:
Asian Journal of Andrology, Vol 22, Iss 6, Pp 623-628 (2020)
Assisted reproductive technologies involving the use of spermatozoa and eggs for in vitro fertilization (IVF) have come as the solution for many infertile couples to become parents. However, in some cases, the use of ejaculated spermatozoa delivers p
Externí odkaz:
https://doaj.org/article/b9a7d1b778b7466aa1a820127eb32f59
Publikováno v:
International Journal of Vaccine Theory, Practice, and Research. 3:818-846
For the first time in medical history, the result of a laboratory assay (RT-qPCR) was used as the sole criterion to diagnose a disease (Covid-19) without any rating of clinical symptoms and to justify the implementation of population-wide non-pharmac
Autor:
Werner Bergholz, Klaus Steger
Publikováno v:
Journal of Biomedical Research & Environmental Sciences. 4:050-063
Background: Based on available data on male fertility adverse effects after COVID-19 injections, we draw the reader´s attention to open questions and undeniable risks of the new RNA-based vaccine technology. Methods: Review and reanalysis of publish
Autor:
Undraga Schagdarsurengin, Angela Lammert, Natalie Schunk, Diana Sheridan, Stefan Gattenloehner, Klaus Steger, Florian Wagenlehner, Temuujin Dansranjavin
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background Human cancer cells often exhibit impaired IGF2 expression and the underlying mechanisms are multifaceted and complex. Besides the well-known imprinting control region IGF2/H19-ICR, the involvement of a differentially methylated re
Externí odkaz:
https://doaj.org/article/104d1d67a6c94062a0cd74925f8427cb
Autor:
Simon Schneider, Farhad Shakeri, Christian Trötschel, Lena Arévalo, Alexander Kruse, Andreas Buness, Ansgar Poetsch, Klaus Steger, Hubert Schorle
Publikováno v:
Cells, Vol 9, Iss 8, p 1789 (2020)
Protamines are the safeguards of the paternal sperm genome. They replace most of the histones during spermiogenesis, resulting in DNA hypercondensation, thereby protecting its genome from environmental noxa. Impaired protamination has been linked to
Externí odkaz:
https://doaj.org/article/5652533a90f64a1eac9e22a61d733466
Autor:
Alexander Brobeil, Fabian Kämmerer, Claudia Tag, Klaus Steger, Stefan Gattenlöhner, Monika Wimmer
Publikováno v:
Biomolecules, Vol 5, Iss 2, Pp 485-504 (2015)
The present study shows a new connection of protein tyrosine phosphatase interacting protein 51 (PTPIP51) to the nuclear factor κB (NFκB) signalling pathway. PTPIP51 mRNA and protein expression is regulated by RelA. If bound to the PTPIP51 promoter
Externí odkaz:
https://doaj.org/article/f545f31954c94546b227617dea6c1801
Autor:
Christine Dottermusch-Heidel, Stefanie M. K. Gärtner, Isabel Tegeder, Christina Rathke, Bridlin Barckmann, Marek Bartkuhn, Sudhanshu Bhushan, Klaus Steger, Andreas Meinhardt, Renate Renkawitz-Pohl
Publikováno v:
Biology Open, Vol 3, Iss 6, Pp 444-452 (2014)
During spermiogenesis, haploid spermatids undergo extensive chromatin remodeling events in which histones are successively replaced by more basic protamines to generate highly compacted chromatin. Here we show for the first time that H3K79 methylatio
Externí odkaz:
https://doaj.org/article/ddaf2e4be74a45538ac42eff4b6923e8
Autor:
Agnieszka Paradowska-Dogan, Karin Kielwein, Burkhard T Espey, Jean-Pierre Allam, Hans van der Ven, Klaus Steger, Katrin van der Ven
Publikováno v:
Lasers in Surgery and Medicine. 54:540-553
Background and objectives Previous studies reported that photobiomodulation (PBM) positively affects the mitochondrial respiratory chain in sperm, resulting in improved motility and velocity. As laser settings are not yet fully established, the prese
Publikováno v:
Anatomia, Histologia, Embryologia. 50:271-283
The present study aimed at analysing the effect of Khat plant extract on rat testicular development. Thirty-two weaned male albino rats (4 weeks old) were divided into four groups consisting of eight animals each. While control animals received norma