Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Klaus, Langer"'
Autor:
Christina Barth, Hendrik Spreen, Dennis Mulac, Lucas Keuter, Matthias Behrens, Hans-Ulrich Humpf, Klaus Langer
Publikováno v:
Biomaterials and Biosystems, Vol 7, Iss , Pp 100057- (2022)
Externí odkaz:
https://doaj.org/article/3a693ab179d54976bca5d599dc51f81e
Autor:
Christina Barth, Hendrik Spreen, Dennis Mulac, Lucas Keuter, Matthias Behrens, Hans-Ulrich Humpf, Klaus Langer
Publikováno v:
Biomaterials and Biosystems, Vol 5, Iss , Pp 100032- (2022)
Receptor-mediated active targeting of nanocarriers is a widely investigated approach to specifically address cancerous cells and tissues in the human body. The idea is to use these formulations as drug carriers with enhanced specificity and therefore
Externí odkaz:
https://doaj.org/article/e4da2ab5791f4bbbbae81e4e2f932853
Autor:
Maria Hahn, Viktoria Lindemann, Matthias Behrens, Dennis Mulac, Klaus Langer, Melanie Esselen, Hans-Ulrich Humpf
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Hordenine, a bioactive food compound, has several pharmacological properties and has recently been identified as a dopamine D2 receptor (D2R) agonist. Since the pharmacokinetic profile of hordenine has been described to a limited extent, the present
Externí odkaz:
https://doaj.org/article/d2b45f7325db475cb944ffb067645fd8
Autor:
Sebastian Pieper, Hannah Onafuye, Dennis Mulac, Jindrich Cinatl Jr., Mark N. Wass, Martin Michaelis, Klaus Langer
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2062-2072 (2019)
Background: Nanoparticles are under investigation as carrier systems for anticancer drugs. The expression of efflux transporters such as the ATP-binding cassette (ABC) transporter ABCB1 is an important resistance mechanism in therapy-refractory cance
Externí odkaz:
https://doaj.org/article/8d1f5de7bcb549f99a9d63b4faf90618
Autor:
Hannah Onafuye, Sebastian Pieper, Dennis Mulac, Jindrich Cinatl Jr., Mark N. Wass, Klaus Langer, Martin Michaelis
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 1707-1715 (2019)
Resistance to systemic drug therapy is a major reason for the failure of anticancer therapies. Here, we tested doxorubicin-loaded human serum albumin (HSA) nanoparticles in the neuroblastoma cell line UKF-NB-3 and its ABCB1-expressing sublines adapte
Externí odkaz:
https://doaj.org/article/5689f5d2bf47444c8e464bfaf5e9ac5a
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 1002-1015 (2019)
Background: When nanoparticles (NPs) are applied into a biological fluid, such as blood, proteins bind rapidly to their surface forming a so-called “protein corona”. These proteins are strongly attached to the NP surface and confers them a new bi
Externí odkaz:
https://doaj.org/article/6d8902745d9249a999eca8b981ad4477
Autor:
Angeles Mecate-Zambrano, Swathi Sukumar, Guiscard Seebohm, Kevin Ciminski, André Schreiber, Darisuren Anhlan, Lilo Greune, Ludmilla Wixler, Stephanie Grothe, Nora Caroline Stein, M Alexander Schmidt, Klaus Langer, Martin Schwemmle, Tianlai Shi, Stephan Ludwig, Yvonne Boergeling
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008775 (2020)
Small RNA viruses only have a very limited coding capacity, thus most viral proteins have evolved to fulfill multiple functions. The highly conserved matrix protein 1 (M1) of influenza A viruses is a prime example for such a multifunctional protein,
Externí odkaz:
https://doaj.org/article/fefccbf695be46aa806a99952163c902
Publikováno v:
Polymer International. 72:5-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bc96d3d9e4c5a9942718a10e677b51
https://doi.org/10.1002/pi.6474
https://doi.org/10.1002/pi.6474
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 584 (2021)
Every day, thousands of patients receive erythrocyte concentrates (ECs). They are indispensable for modern medicine, despite their limited resource. Artificial oxygen carriers (AOCs) represent a promising approach to reduce the need for ECs. One form
Externí odkaz:
https://doaj.org/article/8d3c5979718b40f2905862cccc63ade9