Strict blood pressure control following thrombectomy is associated with neuronal injury and poor functional outcome

Autor: Marianne Hahn, Eyad Hayani, Lynn Bitar, Sonja Gröschel, Falk Steffen, Maria Protopapa, Ahmed Othman, Stefan Bittner, Frauke Zipp, Klaus Gröschel, Timo Uphaus

Publikováno v: Annals of Clinical and Translational Neurology, Vol 10, Iss 12, Pp 2255-2265 (2023)

Abstract Objective Mechanical thrombectomy (MT) has become standard treatment in acute ischemic stroke due to large vessel occlusion (LVO). However, optimal blood pressure (BP) management following successful recanalization remains unclear. We aim to

Externí odkaz: https://doaj.org/article/39b2835c1f8a49669a3f77140e76027e

Temporal Patterning of Neurofilament Light as a Blood-Based Biomarker for Stroke: A Systematic Review and Meta-Analysis

Autor: Jasmin D. Sanchez, Richard A. Martirosian, Katherine T. Mun, Davis S. Chong, Irene Lorenzo Llorente, Timo Uphaus, Klaus Gröschel, Teresa A. Wölfer, Steffen Tiedt, Jason D. Hinman, the DEMDAS Study Group

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

Damage to axons is a core feature of ischemic stroke and cerebrovascular disease. The burden of axonal injury is correlated with the acute clinical deficits, the underlying burden of ischemic brain injury, the prognosis of recovery, and may be a mean

Externí odkaz: https://doaj.org/article/d1d8f92658024e82b5f8e03a676abe00

Software‐based analysis of 1‐hour Holter ECG to select for prolonged ECG monitoring after stroke

Autor: Sonja Gröschel, Björn Lange, Katrin Wasser, Marianne Hahn, Rolf Wachter, Klaus Gröschel, Timo Uphaus

Publikováno v: Annals of Clinical and Translational Neurology, Vol 7, Iss 10, Pp 1779-1787 (2020)

Abstract Objective Identification of ischemic stroke patients at high risk for paroxysmal atrial fibrillation (pAF) during 72 hours Holter ECG might be useful to individualize the allocation of prolonged ECG monitoring times, currently not routinely

Externí odkaz: https://doaj.org/article/8247c9cab6d948ccbbb5691c15de5406

Stroke Care Within the COVID-19 Pandemic—Increasing Awareness of Transient and Mild Stroke Symptoms Needed

Autor: Timo Uphaus, Sonja Gröschel, Eyad Hayani, Marianne Hahn, Falk Steffen, Klaus Gröschel

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Background: The COVID-19 pandemic might affect health care resources and alter patient admission to hospital in case of stroke or transient ischemic attack (TIA). We aim to determine whether the COVID-19 pandemic is affecting utilization of recanaliz

Externí odkaz: https://doaj.org/article/d36ae86ff7ad4e15acf3331b257f0a54

Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial

Autor: Tilman Reiff, Hans-Henning Eckstein, Ulrich Mansmann, Olav Jansen, Gustav Fraedrich, Harald Mudra, Dittmar Böckler, Michael Böhm, E Sebastian Debus, Jens Fiehler, Klaus Mathias, Erich B Ringelstein, Jürg Schmidli, Robert Stingele, Ralf Zahn, Thomas Zeller, Wolf-Dirk Niesen, Kristian Barlinn, Andreas Binder, Jörg Glahn, Werner Hacke, Peter Arthur Ringleb, Friedhelm Beyersdorf, Roland-Richard Macharzina, Gabriele Lechner, Carolin Menz, Sabine Schonhardt, Michael Weinbeck, Olga Greb, Dagmar Otto, Thomas Winker, Hermann Berger, Holger Poppert, Andreas Kühnl, Volker Pütz, Kathrin Haase, Ulf Bodechtel, Norbert Weiss, Hendrik Bergert, Johannes Meyne, Justus Groß, Matthias Kruse, Berthold Gerdes, Wolf-Dieter Reinbold, Helge Wuttig, Andreas Maier-Hasselmann, Manuela Segerer, Hans-Hermann Fuchs, Sabine Gass, Christoph Groden, Marco Niedergethmann, Martin Griebe, Michael Rosenkranz, Jürgen Beck, Götz Thomalla, Hermann H. Zeumer, Marek Jauß, Werner Kneist, Martina Kneist, Thomas Staudacher, Alfons Bernhard, Petra Jost, Nico Prey, Jürgen Knippschild, Oliver Kastrup, Martin Köhrmann, Benedikt Frank, Volkmar Bongers, Johannes Hoffmann, Horst-Wilhelm Kniemeyer, Michael Knauth, Kathrin Wasser, Tomislav Stojanovic, Hans Emmert, Josef Tacke, Bernhard Schwalbe, Eun-Mi Nam, Ulrike van Lengerich, Stephan Lowens, Klaus Gröschel, Timo Uphaus, Sonja Gröschel, Stephan Boor, Bernhard Dorweiler, Elisabeth Schmid, Hans Henkes, Thomas Hupp, Oliver Singer, Gerhard Hamann, Michaela Wagner-Heck, Sibylle Kerth-Krick, Metin Kilic, Peter Huppert, Kurt Niederkorn, Johannes Fruhwirth, Günther Klein, Ulrich Pulkowski, Karsten Jöster, Jens-Henning Wacks, Egbert Kloppmann, Bijan Vatankhah, Silke Hopf-Jensen, Henning Stolze, Stefan Müller-Hülsbeck, Knut Peer Walluscheck, Hans-Michael Schmitt, Albert Grüger, Jörg Seemann, Belay Tilahun, Martin Dichgans, Frank Arne Wollenweber, Angelika Dörr, Adelgunde Zollver, Gabor Gäbel, Günter Hedtmann, Rainer Kollmar, Detlef Claus, Christian Petermann, Stefanie Kirsch, Branko Bosnjak, Johannes Heiß, Holger Mühling, Silke Wunderlich, Peter Nikolaus Sabisch, Georg Gahn, Martin Storck, Sebastian Arnold, Urs Fischer, Jan Gralla, Matthias von Mering, Rüdiger Dißmann, Delia Kirsch, Christoph Schmidauer, Peter Waldenberger, Martin Furtner, Haiko Kazarians, Peter Breuer, Christian Arning, Jürgen Rieper, Georg Schmidt, Marcel Arnold, Gerhard Schroth, Jens Weise, Jürgen Zanow, Thomas Mayer, Rudolf Töpper, Walter Gross-Fengels, Harald Daum, Ralf Dittrich, Martin Ritter, Bernd Kasprzak, Giovanni Torsello, Carsten Pohlmann, Roland Brüning, Alexander Crispin, Miriam Hofmann, Thomas Müller, Erwin Blessing, Markus Möhlenbruch, Ines Ludwig, Hemasse Amiri

Publikováno v: The Lancet Neurology. 21:877-888

The optimal treatment for patients with asymptomatic carotid artery stenosis is under debate. Since best medical treatment (BMT) has improved over time, the benefit of carotid endarterectomy (CEA) or carotid artery stenting (CAS) is unclear. Randomis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd3183ef64d9c0d46c928b337f093b2
https://doi.org/10.1016/s1474-4422(22)00290-3