Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Klaus, Fellermann"'
Autor:
Torsten Schröder, David Kucharczyk, Florian Bär, René Pagel, Stefanie Derer, Sebastian Torben Jendrek, Annika Sünderhauf, Ann-Kathrin Brethack, Misa Hirose, Steffen Möller, Axel Künstner, Julia Bischof, Imke Weyers, Jörg Heeren, Dirk Koczan, Sebastian Michael Schmid, Senad Divanovic, Daniel Aaron Giles, Jerzy Adamski, Klaus Fellermann, Hendrik Lehnert, Jörg Köhl, Saleh Ibrahim, Christian Sina
Publikováno v:
Molecular Metabolism, Vol 5, Iss 4, Pp 283-295 (2016)
Objective: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with an enhanced risk for liver and cardiovascular diseases and mortality. NAFLD can progress from simple hepatic steatosis to non-alcohol
Externí odkaz:
https://doaj.org/article/71ae4444648c45b9904a1ac57dab0b30
Autor:
Florian Bär, Bandik Föh, René Pagel, Torsten Schröder, Heidi Schlichting, Misa Hirose, Susanne Lemcke, Antje Klinger, Peter König, Christian M Karsten, Jürgen Büning, Hendrik Lehnert, Klaus Fellermann, Saleh M Ibrahim, Christian Sina
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102347 (2014)
Enteroendocrine cells (EEC) produce neuropeptides, which are crucially involved in the maintenance of the intestinal barrier. Hence, EEC dysfunction is suggested to be involved in the complex pathophysiology of inflammatory bowel disease (IBD), which
Externí odkaz:
https://doaj.org/article/d91c14fc92564a9aab5180ab655ceb89
Autor:
Alexander Zoufaly, Jakob P Cramer, Eik Vettorazzi, Friedhelm Sayk, Jan P Bremer, Irmtraut Koop, Andreas de Weerth, Stefan Schmiedel, Sabine Jordan, Katharina Fraedrich, Niels H Asselborn, Martin Nitschke, Christine Neumann-Grutzeck, Tim Magnus, Christoph Rüther, Klaus Fellermann, Rolf K Stahl, Karl Wegscheider, Ansgar W Lohse
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59209 (2013)
The outbreak of Shiga toxin producing E.coli O104:H4 in northern Germany in 2011 was one of the largest worldwide and involved mainly adults. Post-diarrheal hemolytic uremic syndrome (HUS) occurred in 22% of STEC positive patients. This study's aim w
Externí odkaz:
https://doaj.org/article/7f0badab694b49cc93e9b550cd3775b9
Autor:
Sarah Wehrum, Jelena Derova, István Rácz, Roland Greinwald, Klaus Fellermann, Laimas Virginijus Jonaitis, Ingolf Schiefke, Tanju Nacak
Publikováno v:
United European Gastroenterol J
In patients with mesalazine-refractory ulcerative colitis, systemic corticosteroids are the treatment of choice.To evaluate the efficacy and safety of prolonged release budesonide granules for the induction of remission in patients with mesalazine-re
Autor:
Andreas Stallmach, T Kühbacher, Jens Walldorf, N A Dietrich, Thomas Krause, Klaus Fellermann, Niels Teich, Renate Schmelz, Florian Bär, Stefan Schreiber, Carsten Büning, Ulf Helwig, Jürgen Büning
Publikováno v:
Alimentary Pharmacology & Therapeutics. 47:581-587
Background The most common complication after ileal pouch anal anastomosis in up to 50% of patients is an acute pouchitis. The majority of patients respond to antibiotic treatment. However, 10%-15% develops chronic antibiotic-dependent or refractory
Autor:
Maureen J Koslowski, Irmgard Kübler, Mathias Chamaillard, Elke Schaeffeler, Walter Reinisch, Guoxing Wang, Julia Beisner, Alexander Teml, Laurent Peyrin-Biroulet, Stefan Winter, Klaus R Herrlinger, Paul Rutgeerts, Séverine Vermeire, Rachel Cooney, Klaus Fellermann, Derek Jewell, Charles L Bevins, Matthias Schwab, Eduard F Stange, Jan Wehkamp
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4496 (2009)
Reduced expression of Paneth cell antimicrobial alpha-defensins, human defensin (HD)-5 and -6, characterizes Crohn's disease (CD) of the ileum. TCF-4 (also named TCF7L2), a Wnt signalling pathway transcription factor, orchestrates Paneth cell differe
Externí odkaz:
https://doaj.org/article/6837cf568a854f24b2bbe8a2472f4905
Autor:
Markus Huber-Lang, Jürgen Büning, Sophie Preisker, Kerstin Skibbe, Christian M. Karsten, Claudia Kemper, Karen Ebbert, Marijana Basic, Admar Verschoor, Christian Sina, André Bleich, Annika Sünderhauf, Klaus Fellermann, Stefanie Derer
Publikováno v:
Molecular Immunology. 90:227-238
The complement system not only plays a critical role in efficient detection and clearance of bacteria, but also in intestinal immune homeostasis as mice deficient for key complement components display enhanced intestinal inflammation upon experimenta
Autor:
Stefanie Derer, Swantje Mindorf, Marc Ehlers, Mette Vesterhus, Bianca Teegen, Hendrik Lehnert, Tobias Korf, Peter Schemmer, Florian Bär, Maike Anna Michaels, Thomas Nitzsche, Christoph M. Hammers, Laila Widmann, Lars Komorowski, Christian Sina, Johannes R. Hov, Daniel Gotthardt, Sebastian Torben Jendrek, Klaus Fellermann, Karl Heinz Weiss, Torsten Schröder, Tom H. Karlsen, Evaggelia Liaskou
Publikováno v:
Gut. 66:137-144
Objective: Pancreatic autoantibodies (PABs), comprising antibodies against glycoprotein 2 (anti-GP2), are typically associated with complicated phenotypes in Crohn's disease, but have also been observed with variable frequencies in patients with UC.
Autor:
Klaus Fellermann, Axel Dignass, N Müller, Daniel C. Baumgart, Eduard F. Stange, Jürgen Büning, K.J Schmidt, Hendrik Lehnert, Klaus Herrlinger
Publikováno v:
Journal of Crohn's and Colitis. 10:31-37
Background and aims: Tacrolimus is recommended for the treatment of steroid-refractory ulcerative colitis (UC). Concomitantly started purine analogues (PAs) are used for the maintenance of remission, though their therapeutic relevance remains uncerta