Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Klaudia Laborc"'
Autor:
Swapnil Gavade, Qiang Wei, Colin Johnston, Savannah Kounelis, Klaudia Laborc, Huda Akil, Joanna L. Spencer-Segal
Stress hormone signaling via the glucocorticoid receptor (GR) modulates vulnerability to stress-related disorders, but whether GR influences how the brain encodes contextual experience is unknown. Mice with lifelong GR overexpression in forebrain glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e085d38d8a3c98c14333ab140b4c0b0c
https://doi.org/10.1101/2022.01.13.476185
https://doi.org/10.1101/2022.01.13.476185
Autor:
Swapnil Gavade, Qiang Wei, Colin Johnston, Savannah Kounelis-Wuillaume, Klaudia Laborc, Salisha Baranwal, Huda Akil, Joanna L. Spencer-Segal
Publikováno v:
eneuro. 9:ENEURO.0126-22.2022
Glucocorticoid signaling influences hippocampal-dependent behavior and vulnerability to stress-related neuropsychiatric disorders. In mice, lifelong overexpression of glucocorticoid receptor (GR) in forebrain excitatory neurons altered exploratory be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1ef4c1c8dc0c632933879300e8e44d
https://doi.org/10.1523/eneuro.0126-22.2022
https://doi.org/10.1523/eneuro.0126-22.2022
Autor:
Scott J. Denstaedt, Theodore J. Standiford, Benjamin H. Singer, Klaudia Laborc, Joanna L. Spencer-Segal, Michael W. Newstead, Xianying Zeng
Publikováno v:
Shock
Pneumonia is the leading cause of sepsis and septic shock. Patients who survive pneumonia are vulnerable to long-term complications including increased risk of neurocognitive dysfunction. This study investigated the immune response and long-term comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfa6232c525d57580b02bdc1fcbc6fa
https://doi.org/10.1097/shk.0000000000001435
https://doi.org/10.1097/shk.0000000000001435
Autor:
Joanna Spencer-Segal, Swapnil Gavade, Qiang Wei, Colin Johnston, Savannah Kounelis, Klaudia Laborc, Huda Akil
Publikováno v:
Biological Psychiatry. 91:S359
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4484680628b3bfa1531b359de9c48528
https://doi.org/10.1016/j.biopsych.2022.02.902
https://doi.org/10.1016/j.biopsych.2022.02.902
Autor:
Klaudia Laborc, Benjamin H. Singer, Joanna L. Spencer-Segal, Khyati Somayaji, Stanley J. Watson, Huda Akil, Theodore J. Standiford
Publikováno v:
Psychoneuroendocrinology
Severe acute stressors are known to trigger mood disorders in humans. Sepsis represents one such stressor, and survivors often suffer long term from psychiatric morbidity. We hypothesized that sepsis leads to lasting changes in neural circuits involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e91d077c3e6029868f0170020d72275
https://europepmc.org/articles/PMC7845932/
https://europepmc.org/articles/PMC7845932/
Autor:
Alexander Hjelmaas, Scott J. Denstaedt, Michael W. Newstead, Theodore J. Standiford, Xianying Zeng, Klaudia Laborc, Joanna L. Spencer-Segal, Huda Akil, Benjamin H. Singer, Anne P. Zhao
Publikováno v:
The Journal of Immunology. 200:3188-3200
Sepsis commonly results in acute and chronic brain dysfunction, which dramatically increases the morbidity associated with this common disease. Chronic brain dysfunction in animal models of sepsis survival is linked to persistent neuroinflammation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff25b18c836240dd5f20abeb687e753
https://doi.org/10.4049/jimmunol.1700834
https://doi.org/10.4049/jimmunol.1700834
SAT-358 Corticosterone Treatment during Sepsis Results in a Primary Adrenal Defect in Male Survivors
Autor:
Gary D. Hammer, Savannah Kounelis, Huda Akil, Joanna L. Spencer-Segal, Yewei Xing, Klaudia Laborc
Publikováno v:
Journal of the Endocrine Society
Abnormalities of adrenal gland function have been described in survivors of prolonged critical illness, but whether an acute inflammatory illness such as sepsis causes lasting changes in adrenal function is unknown. Critically ill patients with sepsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ea5be6153ec027548709b76d2ef93d
http://europepmc.org/articles/PMC6552543
http://europepmc.org/articles/PMC6552543