Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Klaudia Giehl"'
Autor:
Rebekka Geißert, Angela Lammert, Stefanie Wirth, Rabea Hönig, Dirk Lohfink, Monika Unger, Denis Pek, Konstantin Schlüter, Theresa Scheftschik, Daniel J. Smit, Manfred Jücker, Andre Menke, Klaudia Giehl
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract K-Ras is the most frequently mutated Ras variant in pancreatic, colon and non-small cell lung adenocarcinoma. Activating mutations in K-Ras result in increased amounts of active Ras-GTP and subsequently a hyperactivation of effector proteins
Externí odkaz:
https://doaj.org/article/6ad39e31b6e94163a40b075a091f8050
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4258 (2022)
A Clostridioides difficile infection (CDI) is the most common nosocomial infection worldwide. The main virulence factors of pathogenic C. difficile are TcdA and TcdB, which inhibit small Rho-GTPases. The inhibition of small Rho-GTPases leads to the s
Externí odkaz:
https://doaj.org/article/96544ddb64cf4a32a727f3aa5c8fb099
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2015 (2022)
The annual meeting “Signal Transduction—Receptors, Mediators and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference which is open to all scientists sharing a common interest in the elucidation of the signaling pa
Externí odkaz:
https://doaj.org/article/153fef6c9f66458da3b05aa9ce59d786
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9324 (2021)
Neural crest (NC) cells are highly migratory cells that contribute to various vertebrate tissues, and whose migratory behaviors resemble cancer cell migration and invasion. Information exchange via dynamic NC cell–cell contact is one mechanism by w
Externí odkaz:
https://doaj.org/article/b1866d9fa0a549fe9ef8ff8e7554e16a
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2728 (2020)
The annual meeting “Signal Transduction–Receptors, Mediators and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating the signalling pathways underl
Externí odkaz:
https://doaj.org/article/6aa59d566d544698a16f65795fad3425
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 227 (2019)
The annual meeting “Signal Transduction—Receptors, Mediators, and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating signaling pathways in physiol
Externí odkaz:
https://doaj.org/article/7e5a4893f5354ccc8dc0a90ef93bbfa5
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 549 (2018)
The annual “Joint Meeting Signal Transduction—Receptors, Mediators and Genes” of the Signal Transduction Society (STS) aims to be an interdisciplinary forum for researchers who share a common interest in deciphering signal transduction pathways
Externí odkaz:
https://doaj.org/article/4d02483f6fea45bc9187a125181cd69c
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121589 (2015)
Morphological alterations of cells can lead to modulation of gene expression. An essential link is the MKL1-dependent activation of serum response factor (SRF), which translates changes in the ratio of G- and F-actin into mRNA transcription. SRF acti
Externí odkaz:
https://doaj.org/article/8fb70c186dd74f0cbf5ac52f95d795fe
Publikováno v:
International Journal for Numerical Methods in Biomedical Engineering. 39
The primary cause for cancer-related death is metastasis, and although this phenomenon is the hallmark of cancer, it remains poorly understood. Since studies on the underlying mechanisms are still demanding by experimental means prognostic tools base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be41e5f04bf9e56f0ea5f4defa4703c3
https://doi.org/10.1002/cnm.3679
https://doi.org/10.1002/cnm.3679
Autor:
Laura Scharlibbe, Klaudia Giehl, Andre Menke, Dirk Lohfink, Julia R. Seiz, Hendrik Ungefroren, Johannes Klinke, Marisa Heipel
Publikováno v:
Biological Chemistry. 401:517-531
Rac1 is a ubiquitously expressed Rho GTPase and an important regulator of the actin cytoskeleton. Its splice variant Rac1b exhibits a 19-amino acid (aa) in-frame insertion and is predominantly active. Both proteins were described in tumorigenesis or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97c72b53abcfb2ae03bebbbdb198d6e
https://doi.org/10.1515/hsz-2019-0329
https://doi.org/10.1515/hsz-2019-0329