Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Klaudia Bagienski"'
Autor:
Thorsten Klampfl, Jelena D Milosevic, Ana Puda, Andreas Schönegger, Klaudia Bagienski, Tiina Berg, Ashot S Harutyunyan, Bettina Gisslinger, Elisa Rumi, Luca Malcovati, Daniela Pietra, Chiara Elena, Matteo Giovanni Della Porta, Lisa Pieri, Paola Guglielmelli, Christoph Bock, Michael Doubek, Dana Dvorakova, Nada Suvajdzic, Dragica Tomin, Natasa Tosic, Zdenek Racil, Michael Steurer, Sonja Pavlovic, Alessandro M Vannucchi, Mario Cazzola, Heinz Gisslinger, Robert Kralovics
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77819 (2013)
Exome sequencing of primary tumors identifies complex somatic mutation patterns. Assignment of relevance of individual somatic mutations is difficult and poses the next challenge for interpretation of next generation sequencing data. Here we present
Externí odkaz:
https://doaj.org/article/f0ebf7fb82cc41188bd664f89dc8a83f
Autor:
Thorsten Klampfl, Bettina Gisslinger, Tiina Berg, Ashot S. Harutyunyan, Robert Kralovics, Heinz Gisslinger, Klaudia Bagienski
Publikováno v:
Leukemia. 25:1782-1784
Rare germline variants in regions of loss of heterozygosity may influence clinical course of hematological malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d818a2780c61d3f2bbb4cb4b73a1c80
https://doi.org/10.1038/leu.2011.150
https://doi.org/10.1038/leu.2011.150
Autor:
Tiina Berg, Harini Nivarthi, Ciara Cleary, Francesco Passamonti, Ilaria Carola Casetti, Klaudia Bagienski, Richard Moriggl, Cesare Astori, Marta Bellini, Daniela Pietra, Elisa Rumi, Robert Kralovics, Ashot S. Harutyunyan, Mario Cazzola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3c54bd703fe348837da8db1fcdea4
http://hdl.handle.net/11383/2023343
http://hdl.handle.net/11383/2023343
Autor:
Christoph Bock, Ciara Cleary, Emanuela Sant'Antonio, Martin Schalling, Jelena D. Milosevic, Ashot S. Harutyunyan, Chiara Milanesi, Gregory I. Vladimer, Elisa Rumi, Bettina Gisslinger, Giulio Superti-Furga, Fiorella Schischlik, Tiina Berg, Nicole C.C. Them, Heinz Gisslinger, Chiara Elena, Ilaria Carola Casetti, Melanie Six, Thorsten Klampfl, Virginia Valeria Ferretti, Robert Kralovics, Klaudia Bagienski, Daniela Pietra, Harini Nivarthi, Mario Cazzola, Cristiana Pascutto, Andreas Schönegger, Doris Chen, Luca Malcovati
Publikováno v:
The New England journal of medicine. 369(25)
BACKGROUND Approximately 50 to 60% of patients with essential thrombocythemia or primary myelofibrosis carry a mutation in the Janus kinase 2 gene (JAK2), and an additional 5 to 10% have activating mutations in the thrombopoietin receptor gene (MPL).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba1311807149436f3fee52bef5b18ac
https://pubmed.ncbi.nlm.nih.gov/24645956
https://pubmed.ncbi.nlm.nih.gov/24645956
Autor:
Ilaria Iacobucci, Ashot S. Harutyunyan, Roland Jäger, Lisa Pieri, Tiina Berg, Paola Guglielmelli, Alessandro M. Vannucchi, Robert Kralovics, Klaudia Bagienski, Elisa Rumi, Daniela Pietra, Bettina Gisslinger, Giovanni Martinelli, Francesco Passamonti, Martin Schalling, Thorsten Klampfl, Heinz Gisslinger, Damla Olcaydu, Mario Cazzola
Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) are clonal myeloid disorders with increased production of terminally differentiated cells. The disease course is generally chronic, but some patients show disease progression (sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab400b25a5a3705952b116bb1f35a5db
http://hdl.handle.net/11383/2023359
http://hdl.handle.net/11383/2023359
Autor:
Francesco Passamonti, Ilaria Carola Casetti, Chiara Elena, Thorsten Klampfl, Daniela Pietra, Robert Kralovics, Ashot S. Harutyunyan, Mario Cazzola, Cristiana Pascutto, Elisa Rumi, Klaudia Bagienski, Tiina Berg
Myeloproliferative neoplasms (MPN) include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). These disorders may undergo phenotypic shifts, and may specifically evolve into secondary myelofibrosis (MF) or acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4357f7da19fd66ff80f4336466e514a7
http://hdl.handle.net/11383/2023254
http://hdl.handle.net/11383/2023254
Autor:
Jelena D Milosevic Feenstra, Harini Nivarthi, Heinz Gisslinger, Emilie Leroy, Elisa Rumi, Ilyas Chachoua, Klaudia Bagienski, Blanka Kubesova, Daniela Pietra, Bettina Gisslinger, Roland Jäger, Doris Chen, Tiina Berg, Martin Schalling, Michael Schuster, Christoph Bock, Stefan N. Constantinescu, Mario Cazzola, Robert Kralovics
Publikováno v:
Blood. 126:606-606
Essential thrombocythemia (ET) and primary myelofibrosis (PMF) are chronic myeloproliferative neoplasms (MPN) characterized by clonal hematopoiesis and hyperproliferation of terminally differentiated myeloid cells. Most of the cases are sporadic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8dc977178b17f900955150c935a5eb2
https://doi.org/10.1182/blood.v126.23.606.606
https://doi.org/10.1182/blood.v126.23.606.606
Autor:
Heinz Gisslinger, Bettina Gisslinger, Veronika Buxhofer-Ausch, Leonhard Muellauer, Klaudia Bagienski, Robert Kralovics, Nicole C.C. Them, Martin Schalling, Guenther Nirnberger, Ashot S. Harutyunyan, Juergen Thiele, Jelena D. Milosevic, Tiina Berg
Publikováno v:
Blood. 124:3167-3167
The genomic landscape of myeloproliferative neoplasms (MPNs) has altered dramatically due to the recent discovery of somatic mutations of calreticulin (CALR). This discovery enables for the first time molecular information, in addition to JAK2V617F,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d405086f5dc2f1630c5d35cb3578c7
https://doi.org/10.1182/blood.v124.21.3167.3167
https://doi.org/10.1182/blood.v124.21.3167.3167
Autor:
Christoph Klade, Veronika Buxhofer-Ausch, Robert Kralovics, Guenther Gastl, Richard Greil, Josef Thaler, Klaudia Bagienski, Ernst Schloegl, Oleh Zahriychuk, Nicole C.C. Them, Tiina Berg, Heinz Gisslinger
Publikováno v:
Blood. 122:1589-1589
Polycythemia vera (PV) is one of the most common type of BCR-ABL negative myeloproliferative neoplasms. It is characterized by elevated erythrocyte mass, variable presence of thrombocytosis and leukocytosis, predisposition to secondary myelofibrosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c074e35a4d238709436ac5a3f57d67c2
https://doi.org/10.1182/blood.v122.21.1589.1589
https://doi.org/10.1182/blood.v122.21.1589.1589
Autor:
Jelena D. Milosevic, Elisa Rumi, Daniela Pietra, Klaudia Bagienski, Tiina Berg, Emanuela Sant'Antonio, Anna Colombo, Francesco Ripamonti, Mario Cazzola, Robert Kralovics
Publikováno v:
Blood. 122:4101-4101
Allogeneic bone marrow transplantation (ABMT) is so far the only curative treatment option for patients with myelofibrosis (MF), although it carries risk of treatment related mortality and relapse. The effect of somatic mutations present in the clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8e6045921df9f13066ee2096b3ff0c
https://doi.org/10.1182/blood.v122.21.4101.4101
https://doi.org/10.1182/blood.v122.21.4101.4101