Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Klas J. F. Petersson"'
Publikováno v:
Pharmaceutical Research. 26:2174-2185
To investigate the use of adaptive transformations to assess the parameter distributions in population modeling. The logit, box-cox, and heavy tailed transformations were investigated. Each one was used in conjunction with the standard (exponential)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4854fdbcaa25a99c8c3ecfacba2274dc
https://doi.org/10.1007/s11095-009-9931-1
https://doi.org/10.1007/s11095-009-9931-1
Publikováno v:
Clinical Pharmacology & Therapeutics. 85:409-417
A mechanistic pharmacokinetic/pharmacodynamic model is presented, characterizing the time course of prolactin in healthy as well as schizophrenic subjects following the administration of various doses and formulations of the antipsychotic drugs rispe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a218516d1137c792d10857623d2099
https://doi.org/10.1038/clpt.2008.234
https://doi.org/10.1038/clpt.2008.234
Publikováno v:
Aaps Journal, 15, 2, pp. 533-41
Aaps Journal, 15, 533-41
Aaps Journal, 15, 533-41
Item does not contain fulltext Prolactin elevation is a side effect of all currently available D2 receptor antagonists used in the treatment of schizophrenia. Prolactin elevation is the result of a direct antagonistic D2 effect blocking the tonic inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fa7677df96038e08d922d52c46ddfa
https://hdl.handle.net/2066/117462
https://hdl.handle.net/2066/117462
Autor:
An Vermeulen, Ahmed Abbas Suleiman, V. Pilla Reddy, Lena E. Friberg, Klas J. F. Petersson, Johannes H. Proost
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, 1:e1. Wiley
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
A major problem in the treatment of schizophrenic patients with current antipsychotic drugs, mainly acting as dopamine-2 receptor antagonists, is the occurrence of side effects such as extrapyramidal symptoms (EPS). Meta-analyses of summary data of E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587403c17871c14753ecbcdf376b6957
https://research.rug.nl/en/publications/ef148abd-5322-401e-a395-56a295cd17b9
https://research.rug.nl/en/publications/ef148abd-5322-401e-a395-56a295cd17b9
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 37(5)
Computer models of biological systems grow more complex as computing power increase. Often these models are defined as differential equations and no analytical solutions exist. Numerical integration is used to approximate the solution; this can be co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d362c144f645b71b1915e9ae6da3b7
https://pubmed.ncbi.nlm.nih.gov/20878453
https://pubmed.ncbi.nlm.nih.gov/20878453
Autor:
Jacqueline M. Anderson, Lena E. Friberg, Horst Thiermann, Klas J. F. Petersson, Nicholas A. Buckley, Franz Worek
Publikováno v:
Toxicology Letters. 211:S173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882c5aaa89eff748d018dd655981ac41
https://doi.org/10.1016/j.toxlet.2012.03.784
https://doi.org/10.1016/j.toxlet.2012.03.784
Autor:
Horst Thiermann, Klas J. F. Petersson, Michael Eddleston, R. E. Clutton, Franz Worek, Jacqueline M. Anderson, Nicholas A. Buckley, L. Friburg
Publikováno v:
Toxicology Letters. 196:S326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e985cee46a226fa11b515fcd70a83a
https://doi.org/10.1016/j.toxlet.2010.03.1030
https://doi.org/10.1016/j.toxlet.2010.03.1030