Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Klas Bratteby"'
1
Akademický článek
GMP production of [18F]FE-PE2I on a TRACERLab FX2 N synthesis module, a radiotracer for in vivo PET imaging of the dopamine transport
Autor: Mélodie Ferrat, Mohammad M. Moein, Carmen Cananau, Tetyana Tegnebratt, Paul Saliba, Fredrik Norman, Carsten Steiger, Klas Bratteby, Erik Samén, Kenneth Dahl, Thuy A. Tran
Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Background Parkinson's disease is a neurodegenerative disorder that is characterized by a degeneration of the dopaminergic system. Dopamine transporter (DAT) positron emission tomography (PET) imaging has emerged as a powerful and non-invasi
Externí odkaz: https://doaj.org/article/e65b296c56184589988edeae0e5a7450
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2
Akademický článek
Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [68Ga]Ga-ABY-025 tracer
Autor: Emma Jussing, Mélodie Ferrat, Mohammad M. Moein, Henrik Alfredéen, Tetyana Tegnebratt, Klas Bratteby, Erik Samén, Joachim Feldwisch, Renske Altena, Rimma Axelsson, Thuy A. Tran
Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Background The Affibody molecule, ABY-025, has demonstrated utility to detect human epidermal growth factor receptor 2 (HER2) in vivo, either radiolabelled with indium-111 (111In) or gallium-68 (68Ga). Using the latter, 68Ga, is preferred du
Externí odkaz: https://doaj.org/article/b87d7fa931ac4772bb01e5b99da1ebb9
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3
Akademický článek
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases
Autor: Ruben Smith, Francesca Capotosti, Martin Schain, Tomas Ohlsson, Efthymia Vokali, Jerome Molette, Tanja Touilloux, Valerie Hliva, Ioannis K. Dimitrakopoulos, Andreas Puschmann, Jonas Jögi, Per Svenningsson, Mattias Andréasson, Christine Sandiego, David S. Russell, Patricia Miranda-Azpiazu, Christer Halldin, Erik Stomrud, Sara Hall, Klas Bratteby, Elina Tampio L’Estrade, Ruth Luthi-Carter, Andrea Pfeifer, Marie Kosco-Vilbois, Johannes Streffer, Oskar Hansson
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract A positron emission tomography (PET) tracer detecting α-synuclein pathology will improve the diagnosis, and ultimately the treatment of α-synuclein-related diseases. Here we show that the PET ligand, [18F]ACI-12589, displays good in vitro
Externí odkaz: https://doaj.org/article/8e2d2bdd4dfc4ecea2658cceed5ad9e8
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4
Akademický článek
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
Autor: Klas Bratteby, Charlotte Lund Denholt, Szabolcs Lehel, Ida Nymann Petersen, Jacob Madsen, Maria Erlandsson, Tomas Ohlsson, Matthias Manfred Herth, Nic Gillings
Publikováno v: Pharmaceuticals, Vol 14, Iss 7, p 601 (2021)
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic im
Externí odkaz: https://doaj.org/article/9970e4c34953481b89c3e280c1ae8e6c
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6
In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors
Autor: Fredrik Zetterberg, Kristoffer Peterson, Edvard Torkelsson, Maria Erlandsson, Nic Gillings, Vladimir Shalgunov, Hakon Leffler, Tomas G Olsson, Mengfei Xiong, Matthias M. Herth, Ulf J. Nilsson, Klas Bratteby, Elina T. L’Estrade
Publikováno v: Journal of Medicinal Chemistry. 63:747-755
Glycomimetic drugs have attracted increasing interest as unique targeting vectors or surrogates for endogenous biomolecules. However, it is generally difficult to determine the in vivo pharmacokinetic profile of these compounds. In this work, two gal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cd311416633749e1f81029303072a17
https://doi.org/10.1021/acs.jmedchem.9b01692
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7
Development of the First Aliphatic
Autor: Umberto M, Battisti, Klas, Bratteby, Jesper T, Jørgensen, Lars, Hvass, Vladimir, Shalgunov, Hannes, Mikula, Andreas, Kjær, Matthias Manfred, Herth
Publikováno v: Journal of medicinal chemistry. 64(20)
Pretargeted imaging of nanomedicines have attracted considerable interest because it has the potential to increase imaging contrast while reducing radiation burden to healthy tissue. Currently, the tetrazine ligation is the fastest bioorthogonal reac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a24d8882bf13f3ea23246b86b3b77bb6
https://pubmed.ncbi.nlm.nih.gov/34649424
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10
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
Autor: Nic Gillings, Tomas Ohlsson, Ida Nymann Petersen, Charlotte Lund Denholt, Szabolcs Lehel, Klas Bratteby, Jacob Madsen, Maria Erlandsson, Matthias M. Herth
Publikováno v: Pharmaceuticals, Vol 14, Iss 601, p 601 (2021)
Bratteby, K, Denholt, C L, Lehel, S, Petersen, I N, Madsen, J, Erlandsson, M, Ohlsson, T, Herth, M M & Gillings, N 2021, ' Fully Automated GMP-Compliant Synthesis of [ 18 F]FE-PE2I ', Pharmaceuticals, vol. 14, no. 7, 601 . https://doi.org/10.3390/ph14070601
Pharmaceuticals
Volume 14
Issue 7
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8815d988d7069e4405b7b77b9cb93acc
https://www.mdpi.com/1424-8247/14/7/601
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