Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Klarić, Thomas Stephen"'
Autor:
Fazekas, Csilla, Sipos, Eszter, Klarić, Thomas Stephen, Török, Bibiána, Bellardie, Manon, Erjave, Gordana, Lauc, Gordan, Pivac, Nela, Zelena, Dóra
Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder triggered by exposure to traumatic events and occurs in 10-20% of exposed subjects. The molecular mechanisms contributing to PTSD pathology are poorly understood. N-linked glycos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6d004a7248a906684f783e5fd45f6ace
https://www.bib.irb.hr/1157784
https://www.bib.irb.hr/1157784
Asparagine-linked glycosylation (N-glycosylation) plays a key role in many neurodevelopmental processes, including neural cell adhesion, neurite outgrowth, and axon targeting. However, little is known about the dynamics of N-glycosylation during brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::850300a906986e9acdddd9129954e48a
https://www.bib.irb.hr/1157783
https://www.bib.irb.hr/1157783
The aim of this study was to use immunohistochemistry to investigate the expression of the neural activity-dependent transcription factor Neuronal PAS domain protein 4 (Npas4) in two different rodent models of stroke ; middle cerebral artery occlusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::f1ddb2004a0a5784a397d2c67ed14822
https://www.bib.irb.hr/866103
https://www.bib.irb.hr/866103
Autor:
Tsiminis, Georgios, Klarić, Thomas Stephen, Schartner, Erik, Warren-Smith, Stephen, Lewis, Martin David, Koblar, Simon Andrea, Monro, Tanya
We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::7755ba539c33d05499243e9952aec7c5
https://www.bib.irb.hr/866071
https://www.bib.irb.hr/866071
Autor:
Leong, Wai Khay, Klarić, Thomas Stephen, Lin, Yingxi, Koblar, Simon Andrea, Lewis, Martin David
Background: The neuronal Per-Arnt-Sim domain protein 4 (Npas4) is an important transcriptional regulator of synaptic plasticity and cognition. Specifically Npas4 contributes to the homeostatic balance of excitation and inhibition, by regulating the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::29f3592a127fe30717c400b7fc84007c
https://www.bib.irb.hr/866079
https://www.bib.irb.hr/866079
The aim of this study was to investigate the expression of the neural activity-dependent transcription factor Neuronal PAS domain protein 4 (Npas4) in various rodent models of stroke. Two different models of stroke were used to induce focal cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::534a00b6a8fc2d5065616e18dced0d66
https://www.bib.irb.hr/866085
https://www.bib.irb.hr/866085
Autor:
Klarić, Thomas Stephen
Npas4 is an activity-dependent bHLH PAS transcription factor expressed within neurons of the mammalian central nervous system where it regulates the expression of several genes that are important for neuronal survival and synaptic plasticity. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::9d73d09b7c227afb828b298b495e62ba
https://www.bib.irb.hr/865992
https://www.bib.irb.hr/865992
Autor:
Klarić, Thomas Stephen, Thomas, Paul, Dottori, Mirella, Leong, Wai Khay, Koblar, Simon Andrea, Lewis, Martin David
Purpose: In the adult organism, the activity- dependent transcription factor Npas4 plays an important role in several key aspects of neurobiology including inhibitory synapse formation, neuroprotection and memory. However, little is known regarding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a71ae4214198470edffb997437c616d5
https://www.bib.irb.hr/866099
https://www.bib.irb.hr/866099
Npas4, also called LE-PAS or Nxf, is a brain specific transcription factor of the basic helix-loop-helix PAS family. Members of this family are typically involved in developmental processes and cellular response to environmental stresses. Npas4 is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::8c794ed093dd05da745345402b4d2e3f
https://www.bib.irb.hr/866086
https://www.bib.irb.hr/866086
Autor:
Lewis, Martin David, Bindloss, Colleen, Klarić, Thomas Stephen, Key, Brian, Koblar, Simon Andrea
Purpose: To elucidate the developmental role a NPAS4 which is a member of the neural transcription factor bHLH / PAS family. These factors have key roles during development and in the mature organism. NPAS4 expression is restricted to brain, with min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::0d7531ad71d54ba278384ce2084f3e0f
https://www.bib.irb.hr/866105
https://www.bib.irb.hr/866105