Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Klara Post"'
Autor:
Robert J. Gorelick, Karin Musier-Forsyth, Mark C. Williams, M. Nabuan Naufer, Judith G. Levin, Erik D. Olson, Ioulia Rouzina, Klara Post
Publikováno v:
Retrovirology
Background The nucleocapsid (NC) domain of HIV-1 Gag is responsible for specific recognition and packaging of genomic RNA (gRNA) into new viral particles. This occurs through specific interactions between the Gag NC domain and the Psi packaging signa
Autor:
Stuart F. J. Le Grice, Judith G. Levin, Jennifer T. Miller, Michael D. Powell, Kathryn J. Howard, Amnon Hizi, Klara Post, Jianhui Guo
Publikováno v:
Journal of Virology. 77:7623-7634
Human immunodeficiency virus type 2 (HIV-2) infection is a serious problem in West Africa and Asia. However, there have been relatively few studies of HIV-2 reverse transcriptase (RT), a potential target for antiviral therapy. Detailed knowledge of H
Publikováno v:
Biochemistry. 34:5018-5029
The RNase H domain of murine leukemia virus (MuLV) reverse transcriptase (RT) was replaced with Escherichia coli RNase H, and the effect on RNase H activity and processive DNA synthesis was studied, using RNA-DNA hybrids containing sequences from the
Publikováno v:
Biochemistry. 32:5508-5517
The functional relationship between the polymerase and RNase H domains of reverse transcriptase (RT) was investigated by studying the activities of AKR murine leukemia virus (MuLV) enzymes. In addition to the wild type, an RNase H-minus RT missing th
Autor:
Elizabeth Cramer, Klara Post, Robert J. Gorelick, Pilar Saladores, Judith G. Levin, Karin Musier-Forsyth, Besik Kankia, Swathi Gopalakrishnan, Jianhui Guo, Victoria Yang
Publikováno v:
Nucleic Acids Research
During minus-strand DNA synthesis, RNase H degrades viral RNA sequences, generating potential plus-strand DNA primers. However, selection of the 3′ polypurine tract (PPT) as the exclusive primer is required for formation of viral DNA with the corre
Autor:
Veronika Vetyskova, Monika Zouharova, Lucie Bednarova, Ondřej Vaněk, Petra Sázelová, Václav Kašička, Jiri Vymetal, Jaroslav Srp, Michaela Rumlová, Tatsiana Charnavets, Klara Postulkova, Janne E. Reseland, Kristyna Bousova, Jiri Vondrasek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9293 (2020)
Ameloblastin (Ambn) as an intrinsically disordered protein (IDP) stands for an important role in the formation of enamel—the hardest biomineralized tissue commonly formed in vertebrates. The human ameloblastin (AMBN) is expressed in two isoforms: f
Externí odkaz:
https://doaj.org/article/ef38b291810f497a8957145ed565b8c2
Autor:
Kristyna Bousova, Ivan Barvik, Petr Herman, Kateřina Hofbauerová, Lenka Monincova, Pavel Majer, Monika Zouharova, Veronika Vetyskova, Klara Postulkova, Jiri Vondrasek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4323 (2020)
Molecular determinants of the binding of various endogenous modulators to transient receptor potential (TRP) channels are crucial for the understanding of necessary cellular pathways, as well as new paths for rational drug designs. The aim of this st
Externí odkaz:
https://doaj.org/article/58c7f4481a924a9eb60add280fb952de
Autor:
D McKelvin, S C Hu, Robert J. Crouch, D L Court, Klara Post, M Zweig, Brenda I. Gerwin, Judith G. Levin
Publikováno v:
Journal of virology. 62(11)
The functional organization of the murine leukemia virus reverse transcriptase was investigated by expressing a molecular clone containing AKR MuLV reverse transcriptase-coding sequences in Escherichia coli. A purified preparation of the expressed en