Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Klara Lhotova"'
Autor:
Jana Soukupova, Petra Zemankova, Klara Lhotova, Marketa Janatova, Marianna Borecka, Lenka Stolarova, Filip Lhota, Lenka Foretova, Eva Machackova, Viktor Stranecky, Spiros Tavandzis, Petra Kleiblova, Michal Vocka, Hana Hartmannova, Katerina Hodanova, Stanislav Kmoch, Zdenek Kleibl
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195761 (2018)
Carriers of mutations in hereditary cancer predisposition genes represent a small but clinically important subgroup of oncology patients. The identification of causal germline mutations determines follow-up management, treatment options and genetic c
Externí odkaz:
https://doaj.org/article/a5679d53e0984ffc8bfbd8317bc2a066
Autor:
Marketa Janatova, Michal Zikan, Klara Lhotova, Michal Vocka, Petra Kleiblova, Zdeněk Kleibl, Jana Soukupova, Lenka Foretová
Publikováno v:
Klinicka Onkologie. 34
Ovarian cancer is one of the most common gynecologic cancers with the highest mortality rate over a long period. Genetic predisposition to ovarian cancer is unusually high. In the Czech Republic, causal mutation in any ovarian cancer predisposition g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbd32e8cbfacae26cd75cacea708ee7
https://doi.org/10.48095/ccko202126
https://doi.org/10.48095/ccko202126
Autor:
Klara Lhotova, Lenka Stolarova, Petra Zemankova, Michal Vocka, Marketa Janatova, Marianna Borecka, Marta Cerna, Sandra Jelinkova, Jan Kral, Zuzana Volkova, Marketa Urbanova, Petra Kleiblova, Eva Machackova, Lenka Foretova, Jana Hazova, Petra Vasickova, Filip Lhota, Monika Koudova, Leona Cerna, Spiros Tavandzis, Jana Indrakova, Lucie Hruskova, Marcela Kosarova, Radek Vrtel, Viktor Stranecky, Stanislav Kmoch, Michal Zikan, Libor Macurek, Zdenek Kleibl, Jana Soukupova
Publikováno v:
Cancers
Volume 12
Issue 4
Cancers, Vol 12, Iss 956, p 956 (2020)
Volume 12
Issue 4
Cancers, Vol 12, Iss 956, p 956 (2020)
Ovarian cancer (OC) is the deadliest gynecologic malignancy with a substantial proportion of hereditary cases and a frequent association with breast cancer (BC). Genetic testing facilitates treatment and preventive strategies reducing OC mortality in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a4e2291a883ce7c2e2ece10c51c321a8
https://pubmed.ncbi.nlm.nih.gov/32295079
https://pubmed.ncbi.nlm.nih.gov/32295079
Autor:
Křížová Křížová, Monika Burocziova, Zdeněk Kleibl, Kamila Burdova, Stanislav Kmoch, Jan Hojný, Petra Zemankova, Jan Sevcik, Jaroslav Kotlas, Eva Macháčková, Marketa Janatova, Marta Cerna, Aleš Panczak, Klara Lhotova, Libor Macůrek, Filip Lhota, Martina Zimovjanova, Marianna Borecka, Lenka Stolařová, Kamila Veselá, Michaela Schneiderova, Viktor Stránecký, Ondrej Havranek, Jana Červenková, Jana Soukupova, Michal Vocka, Lenka Foretová, Petra Kleiblova, Spiros Tavandzis
Publikováno v:
Klinicka Onkologie. 32
Background Hereditary mutations in the CHEK2 gene (which encodes CHK2 kinase) contribute to a moderately increased risk of breast cancer (BC) and other cancers. Large variations in the frequency of CHEK2 mutations and the occurrence of variants of un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b35708331504e9dd0fd54280c28c556
https://doi.org/10.14735/amko2019s36
https://doi.org/10.14735/amko2019s36
Autor:
Eva Macháčková, Marketa Janatova, Michal Zikan, Lenka Stolařová, Zdeněk Kleibl, Kamila Veselá, Monika Koudová, Marianna Borecka, Jaroslav Kotlas, Lenka Foretová, Viktor Stránecký, Michal Vocka, Filip Lhota, Spiros Tavandzis, Petra Kleiblova, Petra Zemankova, Aleš Panczak, Klara Lhotova, Jana Soukupova
Publikováno v:
Klinicka Onkologie. 32
BACKGROUND Ovarian cancer is a disease with high mortality. Approximately 1,000 women are diagnosed with ovarian cancer in the Czech Republic annually. Women harboring a mutation in cancer-predisposing genes face an increased risk of tumor developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d27558d4e8f3d2d85609c05a98d9b8
https://doi.org/10.14735/amko2019s72
https://doi.org/10.14735/amko2019s72
Autor:
Lenka Stolarova, Libor Macurek, Aleš Panczak, Klara Lhotova, Marta Cerna, Stanislav Kmoch, Monika Burocziova, Jana Soukupova, Katerina Krizova, Jaroslav Kotlas, Viktor Stranecky, Petra Kleiblova, Kamila Burdova, Marketa Janatova, Jan Hojny, Michal Vocka, Petra Zemankova, Kamila Vesela, Jana Červenková, Jan Sevcik, Ondrej Havranek, Filip Lhota, Zdenek Kleibl, Eva Machackova, Spiros Tavandzis, Martina Zimovjanova, Lenka Foretova, Michaela Schneiderova, Marianna Borecka
Publikováno v:
International journal of cancer. 145(7)
Germline mutations in checkpoint kinase 2 (CHEK2), a multiple cancer-predisposing gene, increase breast cancer (BC) risk; however, risk estimates differ substantially in published studies. We analyzed germline CHEK2 variants in 1,928 high-risk Czech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e562181451ed0efce90310e998849c5
https://pubmed.ncbi.nlm.nih.gov/31050813
https://pubmed.ncbi.nlm.nih.gov/31050813
Autor:
Tomas Zemanek, Marketa Janatova, Beatrice Mohelnikova-Duchonova, Martin Lovecek, Roman Havlik, Čestmír Neoral, Jiri Ehrmann, Bohuslav Melichar, Petra Zemankova, Jana Soukupova, Pavel Soucek, Marianna Borecka, Ondrej Strouhal, Viktor Hlavac, Zdenek Kleibl, Hana Svebisova, Klara Lhotova, Pavel Skalicky
Publikováno v:
Cancer Management and Research
Martin Lovecek,1,* Marketa Janatova,2,* Pavel Skalicky,1 Tomas Zemanek,3 Roman Havlik,1 Jiri Ehrmann,4 Ondrej Strouhal,3 Petra Zemankova,2 Klara Lhotova,2 Marianna Borecka,2 Jana Soukupova,2 Hana Svebisova,3 Pavel Soucek,5 Viktor Hlavac,5 Zdenek Klei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f66c6a0d11c6ec25c800ea0293d33b
https://www.dovepress.com/genetic-analysis-of-subsequent-second-primary-malignant-neoplasms-in-l-peer-reviewed-article-CMAR
https://www.dovepress.com/genetic-analysis-of-subsequent-second-primary-malignant-neoplasms-in-l-peer-reviewed-article-CMAR
Autor:
Eliseos J. Mucaki, Stacey L. Edwards, Marinus J. Blok, Jana Soukupova, Mariana Borecka, Marta Santamariña, Marketa Janatova, Paolo Peterlongo, Ana Vega, Ben C. Shirley, Amanda B. Spurdle, Peter K. Rogan, Gaetana Gambino, Phillip J. Whiley, Lenka Stolarova, Petra Zemankova, O. Diez, Siranoush Manoukian, Thomas van Overeem Hansen, David E. Goldgar, Bernardo Bonanni, Emma Tudini, Sara Gutiérrez-Enríquez, Leslie Burke, Elizabeth Santana dos Santos, Michael T. Parsons, Kathleen Claes, Jan Sevcik, Kim De Leeneer, Melissa A. Brown, Paolo Radice, Maria Caligo, Etienne Rouleau, Sandrine M. Caputo, Alejandro Moles-Fernández, Maria Rossing, Klara Lhotova
Publikováno v:
Biochemistry Publications
HUMAN MUTATION
Human Mutation, 39(12), 2025-2039. Wiley
Human Mutation
HUMAN MUTATION
Human Mutation, 39(12), 2025-2039. Wiley
Human Mutation
© 2018 The Authors. Human Mutation published by Wiley Periodicals, Inc. The widespread use of next generation sequencing for clinical testing is detecting an escalating number of variants in noncoding regions of the genome. The clinical significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29835828575937de15cde6b0b4f3a90d
https://ir.lib.uwo.ca/biochempub/218
https://ir.lib.uwo.ca/biochempub/218
Autor:
Ondrej Strouhal, Jana Soukupova, Pavel Soucek, Martin Lovecek, Marianna Borecka, Tomas Zemanek, Marketa Janatova, Beatrice Mohelnikova-Duchonova, Petra Zemankova, Zdenek Kleibl, Hana Svebisova, Viktor Hlavac, Pavel Skalicky, Klara Lhotova
Publikováno v:
Pancreatology. 18:S31-S32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae2d5f2020058841cad24caa930c3dd
https://doi.org/10.1016/j.pan.2018.05.084
https://doi.org/10.1016/j.pan.2018.05.084
Autor:
Beatrice Mohelnikova-Duchonova, Marketa Janatova, Pavel Skalicky, Tomas Zemanek, Roman Havlik, Jiri Ehrmann, Ondrej Strouhal, Petra Zemankova, Klara Lhotova, Marianna Borecka, Jana Soukupova, Hana Svebisova, Pavel Soucek, Viktor Hlavac, Zdenek Kleibl, Cestmir Neoral, Bohuslav Melichar, Martin Lovecek
Publikováno v:
Pancreatology. 19:S153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7edef41a09ba8bc29a2844d00b54152c
https://doi.org/10.1016/j.pan.2019.05.410
https://doi.org/10.1016/j.pan.2019.05.410