Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Klara, Stefflova"'
Autor:
Elissavet Kentepozidou, Sarah J. Aitken, Christine Feig, Klara Stefflova, Ximena Ibarra-Soria, Duncan T. Odom, Maša Roller, Paul Flicek
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically associating domains (TADs). However, despite the importance and conservation of TADs, the
Externí odkaz:
https://doaj.org/article/291fa0f00ad04f14bfde9e67e60009ab
Autor:
Timothy R. Rebbeck, Charnita Zeigler-Johnson, Klara Stefflova, Jong Park, Esther M. John, Jennifer J. Hu, Stephen Chanock, Ann W. Hsing, Rosalind Eeles, Graham Casey, John Witte, Janet L. Stanford, Elaine A. Ostrander, Robin J. Leach, Ian M. Thompson, Adam S. Kibel, Christine Neslund-Dudas, Benjamin Rybicki, Veda N. Giri, Jianfeng Xu, Amit D. Joshi, Roman Corral, Mariana C. Stern, Sue Ann Ingles, Sara Strom, Kathleen Cooney, LaCreis R. Kidd, Marnita L. Benford, William Isaacs, Brian Henderson, Christopher A. Haiman, Stephen Gallagher, Elaine Spangler, Bao-Li Chang
Background: Genome-wide association studies (GWAS) have identified numerous prostate cancer susceptibility alleles, but these loci have been identified primarily in men of European descent. There is limited information about the role of these loci in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0d5f60ac61214cf7de00fa91df083
https://doi.org/10.1158/1055-9965.c.6514782.v1
https://doi.org/10.1158/1055-9965.c.6514782.v1
Autor:
Timothy R. Rebbeck, Charnita Zeigler-Johnson, Klara Stefflova, Jong Park, Esther M. John, Jennifer J. Hu, Stephen Chanock, Ann W. Hsing, Rosalind Eeles, Graham Casey, John Witte, Janet L. Stanford, Elaine A. Ostrander, Robin J. Leach, Ian M. Thompson, Adam S. Kibel, Christine Neslund-Dudas, Benjamin Rybicki, Veda N. Giri, Jianfeng Xu, Amit D. Joshi, Roman Corral, Mariana C. Stern, Sue Ann Ingles, Sara Strom, Kathleen Cooney, LaCreis R. Kidd, Marnita L. Benford, William Isaacs, Brian Henderson, Christopher A. Haiman, Stephen Gallagher, Elaine Spangler, Bao-Li Chang
Supplementary Materials from Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127ea44f7863af29c760188c7404ac27
https://doi.org/10.1158/1055-9965.22435185.v1
https://doi.org/10.1158/1055-9965.22435185.v1
Autor:
Sarah Leigh-Brown, Angela Goncalves, David Thybert, Klara Stefflova, Stephen Watt, Paul Flicek, Alvis Brazma, John C Marioni, Duncan T Odom
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137367 (2015)
Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk ge
Externí odkaz:
https://doaj.org/article/d8a1019b5ad84ccbbf80157fe88db89a
Autor:
Benoit Ballester, Alejandra Medina-Rivera, Dominic Schmidt, Mar Gonzàlez-Porta, Matthew Carlucci, Xiaoting Chen, Kyle Chessman, Andre J Faure, Alister PW Funnell, Angela Goncalves, Claudia Kutter, Margus Lukk, Suraj Menon, William M McLaren, Klara Stefflova, Stephen Watt, Matthew T Weirauch, Merlin Crossley, John C Marioni, Duncan T Odom, Paul Flicek, Michael D Wilson
Publikováno v:
eLife, Vol 3 (2014)
As exome sequencing gives way to genome sequencing, the need to interpret the function of regulatory DNA becomes increasingly important. To test whether evolutionary conservation of cis-regulatory modules (CRMs) gives insight into human gene regulati
Externí odkaz:
https://doaj.org/article/21320be12e154c6893d6efa380de3b03
Autor:
Sarah J. Aitken, Christine Feig, Duncan T. Odom, Ximena Ibarra-Soria, Elissavet Kentepozidou, Klara Stefflova, Paul Flicek, Maša Roller
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Genome Biology
Genome Biology
Funder: European Molecular Biology Laboratory; doi: http://dx.doi.org/10.13039/100013060
Background: CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically asso
Background: CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5e206c8ab4674b51ddf82e597ab553
Autor:
Claudia Kutter, Stephen Watt, Klara Stefflova, Michael D Wilson, Angela Goncalves, Chris P Ponting, Duncan T Odom, Ana C Marques
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002841 (2012)
A large proportion of functional sequence within mammalian genomes falls outside protein-coding exons and can be transcribed into long RNAs. However, the roles in mammalian biology of long noncoding RNA (lncRNA) are not well understood. Few lncRNAs h
Externí odkaz:
https://doaj.org/article/2eb247cd57444810bc3f6e8b558fa090
Autor:
Klara Stefflova, Matthew C Dulik, Jill S Barnholtz-Sloan, Athma A Pai, Amy H Walker, Timothy R Rebbeck
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14495 (2011)
The ancestry of African-descended Americans is known to be drawn from three distinct populations: African, European, and Native American. While many studies consider this continental admixture, few account for the genetically distinct sources of ance
Externí odkaz:
https://doaj.org/article/9abc33a74fd54bde834e5d0bae71b579
Autor:
Klara Stefflova, Matthew C Dulik, Athma A Pai, Amy H Walker, Charnita M Zeigler-Johnson, Serigne M Gueye, Theodore G Schurr, Timothy R Rebbeck
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7842 (2009)
Population history can be reflected in group genetic ancestry, where genomic variation captured by the mitochondrial DNA (mtDNA) and non-recombining portion of the Y chromosome (NRY) can separate female- and male-specific admixture processes. Genetic
Externí odkaz:
https://doaj.org/article/ea01f4bd15bb49838e63135c6e741854
Publikováno v:
Molecular Imaging, Vol 5 (2006)
Imaging apoptotic cells or tissues after cancer therapy in situ would be a very useful tool for assessing proper treatment conditions and therapeutic outcome. By combining therapeutic and imaging functions, we have designed a multifunctional, membran
Externí odkaz:
https://doaj.org/article/da58776f41004e5883f66df8a9355c11