Epidermal growth factor receptor (EGFR) pathway polymorphisms as predictive markers of cetuximab toxicity in locally advanced head and neck squamous cell carcinoma (HNSCC) in a Spanish population

Autor: Fernandez-Mateos, J, Seijas-Tamayo, R, Mesia, R, Taberna, M, Borgonon, MP, Perez-Ruiz, E, Klain, JCA, Fernandez, SV, Morillo, ED, Lozano, A, Sarmiento, RG, Cruz-Hernandez, JJ, Spanish Head Neck Canc Cooperative

Publikováno v: ORAL ONCOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Objectives: To examine the relationship between polymorphisms of the epidermal growth factor receptor (EGFR) pathway and toxicity in head and neck squamous cell carcinoma (HNSCC) patients treated with cetuximab. Material and methods: Multicenter, ret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::8f881a458ef067034e0cdbacde1a940b
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=9165

Analysis of autophagy gene polymorphisms in Spanish patients with head and neck squamous cell carcinoma.

Autor: Fernández-Mateos J; Medical Oncology Service, University Hospital of Salamanca-IBSAL, Salamanca, 37007, Spain.; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain.; Molecular Medicine Unit- IBSAL, Department of Medicine, University of Salamanca, 37007, Salamanca, Spain.; Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-CSIC, Salamanca, 37007, Spain., Seijas-Tamayo R; Medical Oncology Service, University Hospital of Salamanca-IBSAL, Salamanca, 37007, Spain.; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain., Klain JCA; Medical Oncology Service, University Hospital of Salamanca-IBSAL, Salamanca, 37007, Spain.; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain., Borgoñón MP; Medical Oncology Service, Hospital Universitario Politécnico La Fe, Valencia, 46026, Spain., Pérez-Ruiz E; Division of Medical Oncology, Oncology department, Agencia Sanitaria Hospital Costa del Sol de Marbella, 29603, Marbella, Spain., Mesía R; Medical Oncology Department, Universitat de Barcelona, IDIBELL, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, 08908, Spain., Del Barco E; Medical Oncology Service, University Hospital of Salamanca-IBSAL, Salamanca, 37007, Spain.; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain., Coloma CS; Medical Oncology Service, Hospital Universitario Politécnico La Fe, Valencia, 46026, Spain., Dominguez AR; Division of Medical Oncology, Oncology department, Agencia Sanitaria Hospital Costa del Sol de Marbella, 29603, Marbella, Spain., Daroqui JC; Medical Oncology Service, Hospital Universitario Politécnico La Fe, Valencia, 46026, Spain., Fernández Ruiz E; Otolaryngology Department, Agencia Sanitaria Hospital Costa del Sol de Marbella, Marbella, 29603, Spain., Cruz-Hernández JJ; Medical Oncology Service, University Hospital of Salamanca-IBSAL, Salamanca, 37007, Spain. ttcc@seom.org.; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain. ttcc@seom.org.; Molecular Medicine Unit- IBSAL, Department of Medicine, University of Salamanca, 37007, Salamanca, Spain. ttcc@seom.org.; Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-CSIC, Salamanca, 37007, Spain. ttcc@seom.org., González-Sarmiento R; Biomedical Research Institute of Salamanca (IBSAL), SACYL-University of Salamanca-CSIC, Salamanca, 37007, Spain. gonzalez@usal.es.; Molecular Medicine Unit- IBSAL, Department of Medicine, University of Salamanca, 37007, Salamanca, Spain. gonzalez@usal.es.; Institute of Molecular and Cellular Biology of Cancer (IBMCC), University of Salamanca-CSIC, Salamanca, 37007, Spain. gonzalez@usal.es.

Publikováno v: Scientific reports [Sci Rep] 2017 Jul 31; Vol. 7 (1), pp. 6887. Date of Electronic Publication: 2017 Jul 31.