A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients.

Autor: Morrissey SM; Department of Microbiology and Immunology.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center., Geller AE; Department of Microbiology and Immunology.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center., Hu X; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center., Tieri D; Department of Biochemistry and Molecular Genetics., Ding C; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center., Klaes CK; Department of Oral Immunology and Infectious Diseases, School of Dentistry., Cooke EA; Department of Anesthesiology and Perioperative Medicine., Woeste MR; Department of Microbiology and Immunology.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center., Martin ZC; Department of Anesthesiology and Perioperative Medicine., Chen O; Department of Anesthesiology and Perioperative Medicine., Bush SE; Department of Anesthesiology and Perioperative Medicine., Zhang HG; Department of Microbiology and Immunology., Cavallazzi R; Division of Pulmonary, Critical Care and Sleep Disorders, Department of Medicine., Clifford SP; Department of Anesthesiology and Perioperative Medicine., Chen J; Department of Anesthesiology and Perioperative Medicine., Ghare S; University of Louisville Hepatobiology and Toxicology Center, Departments of Medicine and Pharmacology & Toxicology., Barve SS; University of Louisville Hepatobiology and Toxicology Center, Departments of Medicine and Pharmacology & Toxicology., Cai L; Pediatric Research Institute, Department of Pediatrics., Kong M; Department of Bioinformatics and Biostatistics., Rouchka EC; Department of Computer Science and Engineering, and., McLeish KR; Division of Nephrology and Hypertension, Department of Medicine, University of Louisville, Louisville, Kentucky, USA., Uriarte SM; Department of Oral Immunology and Infectious Diseases, School of Dentistry., Watson CT; Department of Biochemistry and Molecular Genetics., Huang J; Department of Anesthesiology and Perioperative Medicine., Yan J; Department of Microbiology and Immunology.; Division of Immunotherapy, the Hiram C. Polk, Jr., MD, Department of Surgery, Immuno-Oncology Program, James Graham Brown Cancer Center.

Publikováno v: JCI insight [JCI Insight] 2021 May 10; Vol. 6 (9). Date of Electronic Publication: 2021 May 10.

Putative Periodontal Pathogens, Filifactor Alocis and Peptoanaerobacter Stomatis, Induce Differential Cytokine and Chemokine Production by Human Neutrophils.

Autor: Vashishta A; Department of Medicine, School of Medicine, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. aruna.vashishta@louisville.edu., Jimenez-Flores E; Department of Medicine, School of Medicine, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. emeri.jimenez@upr.edu.; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. emeri.jimenez@upr.edu., Klaes CK; Department of Medicine, School of Medicine, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. keith.klaes@louisville.edu., Tian S; Department of Medicine, School of Medicine, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. shifu.tian@pennmedicine.upenn.edu., Miralda I; Department of Microbiology & Immunology, School of Medicine, University of Louisville, 505 S. Hancock St., Louisville, KY 40202, USA. irina.miralda@louisville.edu., Lamont RJ; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. rich.lamont@louisville.edu., Uriarte SM; Department of Medicine, School of Medicine, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. silvia.uriarte@louisville.edu.; Department of Oral Immunology and Infectious Diseases, School of Dentistry, University of Louisville, 570 S. Preston St., Louisville, KY 40202, USA. silvia.uriarte@louisville.edu.; Department of Microbiology & Immunology, School of Medicine, University of Louisville, 505 S. Hancock St., Louisville, KY 40202, USA. silvia.uriarte@louisville.edu.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2019 May 01; Vol. 8 (2). Date of Electronic Publication: 2019 May 01.

Filifactor alocis manipulates human neutrophils affecting their ability to release neutrophil extracellular traps induced by PMA.

Autor: Armstrong CL; 1 Department of Microbiology and Immunology, University of Louisville, USA., Klaes CK; 2 Department of Medicine, University of Louisville, USA., Vashishta A; 2 Department of Medicine, University of Louisville, USA., Lamont RJ; 3 Department of Oral Immunology and Infectious Diseases, University of Louisville, USA., Uriarte SM; 1 Department of Microbiology and Immunology, University of Louisville, USA.; 2 Department of Medicine, University of Louisville, USA.; 3 Department of Oral Immunology and Infectious Diseases, University of Louisville, USA.

Publikováno v: Innate immunity [Innate Immun] 2018 May; Vol. 24 (4), pp. 210-220. Date of Electronic Publication: 2018 Apr 13.