ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.

Autor: van der Weegen Y; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., de Lint K; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands., van den Heuvel D; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Nakazawa Y; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan.; Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Mevissen TET; Howard Hughes Medical Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., van Schie JJM; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands., San Martin Alonso M; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Boer DEC; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., González-Prieto R; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., Narayanan IV; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Klaassen NHM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Wondergem AP; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Roohollahi K; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands., Dorsman JC; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands., Hara Y; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan.; Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Vertegaal ACO; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands., de Lange J; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands., Walter JC; Howard Hughes Medical Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Noordermeer SM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Ljungman M; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.; Department of Environmental Health Sciences, Rogel Cancer Center and Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, USA., Ogi T; Department of Genetics, Research Institute of Environmental Medicine (RIeM), Nagoya University, Nagoya, Japan.; Department of Human Genetics and Molecular Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Wolthuis RMF; Department of Clinical Genetics, Section Oncogenetics, Cancer Center Amsterdam, Amsterdam University Medical Center, Amsterdam, The Netherlands. r.wolthuis@amsterdamumc.nl., Luijsterburg MS; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. m.luijsterburg@lumc.nl.

Publikováno v: Nature cell biology [Nat Cell Biol] 2021 Jun; Vol. 23 (6), pp. 595-607. Date of Electronic Publication: 2021 Jun 09.