Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Klaas Kooistra"'
Publikováno v:
International Journal of Cancer. 109:38-42
Nonfunctional p53 and especially upregulation of Bcl-x(L) result in advanced disease and poor prognosis of patients suffering head and neck squamous cell carcinoma (HNSCC). Aberrancies of Bcl-x(L) and/or p53 in HNSCC lead to inability of anticancer d
Autor:
Klaas Kooistra, Sibrand Poppema, Ewerton Marques Maggio, Renata Rust, Anke van den Berg, Arjan Diepstra
Publikováno v:
Scopus-Elsevier
University of Groningen
Blood, 100(4), 1425-1429. AMER SOC HEMATOLOGY
University of Groningen
Blood, 100(4), 1425-1429. AMER SOC HEMATOLOGY
Large cell lymphomas and Hodgkin disease may develop during the course of chronic lymphocytic leukemia (CLL). In some cases the transformed cells are Epstein-Barr virus (EBV)-positive and not clonally related to the CLL cells. In other cases the tran
Autor:
Marc Castellazzi, Peter Herrlich, Stéphanie Huguier, Klaas Kooistra, Peter Angel, Emmanuel Vial, Alex J. van der Eb, Joël Baguet, Hans van Dam
Publikováno v:
Genes & Development. 12:1227-1239
Cellular transformation can be achieved by constitutive activation of growth-regulatory signaling pathways, which, in turn, activate nuclear transcription factors thought to execute a transformation-specific program of gene expression. Members of the
Publikováno v:
The international journal of neuropsychopharmacology. 16(5)
Bipolar disorder (BD) mania is a psychiatric disorder with multifaceted symptoms. Development of targeted treatments for BD mania may benefit from animal models that mimic multiple symptoms, as opposed to hyperactivity alone. Using the reverse-transl
Publikováno v:
Mini reviews in medicinal chemistry. 7(11)
Viruses can produce viral oncoproteins that drive multiple genetic alterations as the consequence of neoplastic transformation. Viral proteins encoded by onco-related viruses such as polyomavirus SV40 or Epstein-Barr virus are involved in cellular pr
Autor:
Mathieu H.M. Noteborn, Jennifer L. Rohn, Klaas Kooistra, Alexandra Maria Pietersen, Ying-Hui Zhang
Publikováno v:
Journal of virology. 78(18)
Apoptin, a viral death protein derived from chicken anemia virus, displays a number of tumor-specific behaviors. In particular, apoptin is phosphorylated, translocates to the nucleus, and induces apoptosis specifically in tumor or transformed cells,
Autor:
Klaas Kooistra, Mathieu H.M. Noteborn, Niek V. Henriquez, Dominik Mumberg, Bertram Weiss, Ying-Hui Zhang
Publikováno v:
The Journal of general virology. 85(Pt 6)
TT virus (TTV) is widespread among the global population. Its pathogenic nature is still unclear but TTV seems to be more prevalent in cases of hepatitis than in healthy individuals. TTV harbours similarities to chicken anaemia virus (CAV). Here, the
Autor:
Ying-Hui Zhang, Molenaar C, Jennifer L. Rohn, Leliveld, Mathieu H.M. Noteborn, Jan Pieter Abrahams, Klaas Kooistra, Tanke Hj
Publikováno v:
Experimental Cell Research, 289(1), 36-46
Apoptin, a protein derived from chicken anemia virus, induces apoptosis in human transformed or tumor cells but not in normal cells. When produced in bacteria as a recombinant fusion with maltose-binding protein (MBP-Apoptin), Apoptin forms a distinc
Autor:
D. Margriet Ouwens, Johannes L. Bos, Nancy D. de Ruiter, J. Antonie Maassen, Jan Schouten, Gerard C.M. van der Zon, Corina van der Burgt, Hans van Dam, Klaas Kooistra, Andrew P. Carter
Publikováno v:
The EMBO journal. 21(14)
Transcription factor ATF2 regulates gene expression in response to environmental changes. Upon exposure to cellular stresses, the mitogen-activated proteinkinase (MAPK) cascades including SAPK/JNK and p38 can enhance ATF2’s transactivating function
Autor:
Klaas Kooistra, Lydia Visser, Miao Wang, Steven T. Pals, Geert Harms, Anke van den Berg, Tjasso Blokzijl, Ph. M. Kluin, Jan-Lukas Robertus, Rogier M. Reijmers, Rikst Niynke Schakel, Siefano Rosati, Lu-ping Tan
Publikováno v:
Blood. 110:2081-2081
Introduction: B cell Chronic Lymphocytic Leukemia (B-CLL) is characterized by the accumulation of nonproliferating mature-appearing lymphocytes in the blood, marrow, lymph nodes, and spleen. B-CLL behaves like leukemia and is found mostly in the bloo